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Prof. Dr.  Russell John Cox

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Publications

  1. 2004
  2. Efficient synthesis of protected cyclopropyl β-aspartylphosphates

    Adams, L. A., Charmant, J. P. H., Cox, R. J., Walter, M. & Whittingham, W. G., 21 Feb 2004, In: Organic and Biomolecular Chemistry. 2, 4, p. 542-553 12 p.

    Research output: Contribution to journalArticleResearchpeer review

  3. 2003
  4. Diastereoselective Synthesis of Cyclopropane Amino Acids Using Diazo Compounds Generated in Situ

    Adams, L. A., Aggarwal, V. K., Bonnert, R. V., Bressel, B., Cox, R. J., Shepherd, J., De Vicente, J., Walter, M., Whittingham, W. G. & Winn, C. L., 28 Nov 2003, In: Journal of Organic Chemistry. 68, 24, p. 9433-9440 8 p.

    Research output: Contribution to journalArticleResearchpeer review

  5. Rapid and flexible synthesis of 1-deoxy-D-xylulose-5-phosphate, the substrate for 1-deoxy-D-xylulose-5-phosphate reductoisomerase

    Cox, R. J., De Andrés-Gómez, A. & Godfrey, C. R. A., 21 Sept 2003, In: Organic and Biomolecular Chemistry. 1, 18, p. 3173-3177 5 p.

    Research output: Contribution to journalArticleResearchpeer review

  6. The type I rat fatty acid synthase ACP shows structural homology and analogous biochemical properties to type II ACPs

    Reed, M. A. C., Schweizer, M., Szafranska, A. E., Arthur, C., Nicholson, T. P., Cox, R. J., Crosby, J., Crump, M. P. & Simpson, T. J., 7 Feb 2003, In: Organic and Biomolecular Chemistry. 1, 3, p. 463-471 9 p.

    Research output: Contribution to journalArticleResearchpeer review

  7. First in vitro directed biosynthesis of new compounds by a minimal type II polyketide synthase: Evidence for the mechanism of chain length determination

    Nicholson, T. P., Winfield, C., Westcott, J., Crosby, J., Simpson, T. J. & Cox, R. J., 1 Jan 2003, In: Chemical communications. 3, 6, p. 686-687 2 p.

    Research output: Contribution to journalArticleResearchpeer review

  8. 2002
  9. Biosynthesis

    Cox, R. J., 12 Dec 2002, In: Annual Reports on the Progress of Chemistry - Section B. 98, p. 223-251 29 p.

    Research output: Contribution to journalArticleResearchpeer review

  10. Aspartyl phosphonates and phosphoramidates: The first synthetic inhibitors of bacterial aspartate-semialdehyde dehydrogenase

    Cox, R. J., Gibson, J. S., Belén, M. & Martín, M., 1 Dec 2002, In: CHEMBIOCHEM. 3, 9, p. 874-886 13 p.

    Research output: Contribution to journalArticleResearchpeer review

  11. Synthesis and characterisation of acyl carrier protein bound polyketide analogues

    Arthur, C., Cox, R. J., Crosby, J., Rahman, M. M., Simpson, T. J., Soulas, F., Spogli, R., Szafranska, A. E., Westcott, J. & Winfield, C. J., 1 Mar 2002, In: CHEMBIOCHEM. 3, 2-3, p. 253-257 5 p.

    Research output: Contribution to journalArticleResearchpeer review

  12. Kinetic and mechanistic analysis of the malonyl CoA:ACP transacylase from Streptomyces coelicolor indicates a single catalytically competent serine nucleophile at the active site

    Szafranska, A. E., Hitchman, T. S., Cox, R. J., Crosby, J. & Simpson, T. J., 5 Feb 2002, In: Biochemistry. 41, 5, p. 1421-1427 7 p.

    Research output: Contribution to journalArticleResearchpeer review

  13. A new synthesis of phosphoramidates: inhibitors of the key bacterial enzyme aspartate semi-aldehyde dehydrogenase

    Adams, L. A., Cox, R. J., Gibson, J. S., Mayo-Martín, M. B., Walter, M. & Whittingham, W., 1 Jan 2002, In: Chemical communications. 2, 18, p. 2004-2005 2 p.

    Research output: Contribution to journalArticleResearchpeer review

  14. Streptomyces coelicolor phosphopantetheinyl transferase: A promiscuous activator of polyketide and fatty acid synthase acyl carrier proteins

    Cox, R. J., Crosby, J., Daltrop, O., Glod, F., Jarzabek, M. E., Nicholson, T. P., Reed, M., Simpson, T. J., Smith, L. H., Soulas, F., Szafranska, A. E. & Westcott, J., 1 Jan 2002, In: Journal of the Chemical Society. Perkin Transactions 1. 14, p. 1644-1649 6 p.

    Research output: Contribution to journalArticleResearchpeer review

  15. Synthesis and in vitro enzyme activity of an oxa analogue of azi-DAP

    Cox, R. J., Durston, J. & Roper, D. I., 1 Jan 2002, In: Journal of the Chemical Society. Perkin Transactions 1. 8, p. 1029-1035 7 p.

    Research output: Contribution to journalArticleResearchpeer review

  16. Published

    Biosynthesis

    Cox, R. J., 2002, In: Annual Reports on the Progress of Chemistry - Section B.

    Research output: Contribution to journalArticleResearchpeer review

  17. 2001
  18. Design and utility of oligonucleotide gene probes for fungal polyketide synthases

    Nicholson, T. P., Rudd, B. A. M., Dawson, M., Lazarus, C. M., Simpson, T. J. & Cox, R. J., 1 Jan 2001, In: Chemistry and Biology. 8, 2, p. 157-178 22 p.

    Research output: Contribution to journalArticleResearchpeer review

  19. Difluoromethylene analogues of aspartyl phosphate: The first synthetic inhibitors of aspartate semi-aldehyde dehydrogenase

    Cox, R. J., Hadfield, A. T. & Mayo-Martín, M. B., 1 Jan 2001, In: Chemical communications. 1, 18, p. 1710-1711 2 p.

    Research output: Contribution to journalArticleResearchpeer review

  20. Is N-acetylornithine aminotransferase the real N-succinyl-ll-diaminopimelate aminotransferase in Escherichia coli and Mycobacterium smegmatis?

    Cox, R. J. & Wang, P. S. H., 1 Jan 2001, In: Journal of the Chemical Society. Perkin Transactions 1. 1, 17, p. 2006-2008 3 p.

    Research output: Contribution to journalComment/debateResearchpeer review

  21. Synthesis and in vitro enzyme activity of aza, oxa and thia derivatives of bacterial cell wall biosynthesis intermediates

    Cox, R. J. & Wang, P. S. H., 1 Jan 2001, In: Journal of the Chemical Society. Perkin Transactions 1. 1, 17, p. 2022-2034 13 p.

    Research output: Contribution to journalArticleResearchpeer review

  22. Published

    Stoichiometric analysis of the minimal actinorhodin polyketide synthase system

    Nettleship, J. E., Cox, R. J. & Simpson, T. J., 2001, In: Amino Acids (Vienna).

    Research output: Contribution to journalArticleResearchpeer review

  23. 2000
  24. Synthesis and in vitro enzyme activity of peptide derivatives of bacterial cell wall biosynthesis inhibitors

    Cox, R. J., Jenkins, H., Schouten, J. A., Stentiford, R. A. & Wareing, K. J., 1 Dec 2000, In: Journal of the Chemical Society, Perkin Transactions 1. 13, p. 2023-2036 14 p.

    Research output: Contribution to journalArticleResearchpeer review

  25. Bacterial diaminopimelate metabolism as a target for antibiotic design

    Cox, R. J., Sutherland, A. & Vederas, J. C., May 2000, In: Bioorganic and Medicinal Chemistry. 8, 5, p. 843-871 29 p.

    Research output: Contribution to journalArticleResearchpeer review