Publications
- 2007
An antibiotic produced by an insect-pathogenic bacterium suppresses host defenses through phenoloxidase inhibition
Eleftherianos, I., Boundy, S., Joyce, S. A., Aslam, S., Marshall, J. W., Cox, R. J., Simpson, T. J., Clarke, D. J., Ffrench-Constant, R. H. & Reynolds, S. E., 13 Feb 2007, In: Proceedings of the National Academy of Sciences of the United States of America. 104, 7, p. 2419-2424 6 p.Research output: Contribution to journal › Article › Research › peer review
Biosynthesis of the 2-pyridone tenellin in the insect pathogenic fungus Beauveria bassiana
Eley, K. L., Halo, L. M., Song, Z., Powles, H., Cox, R. J., Bailey, A. M., Lazarus, C. M. & Simpson, T. J., 12 Feb 2007, In: CHEMBIOCHEM. 8, 3, p. 289-297 9 p.Research output: Contribution to journal › Article › Research › peer review
Characterisation of 3-methylorcinaldehyde synthase (MOS) in Acremonium strictum: First observation of a reductive release mechanism during polyketide biosynthesis
Bailey, A. M., Cox, R. J., Harley, K., Lazarus, C. M., Simpson, T. J. & Skellam, E., 1 Jan 2007, In: Chemical communications. 39, p. 4053-4055 3 p.Research output: Contribution to journal › Article › Research › peer review
Mupirocin H, a novel metabolite resulting from mutation of the HMG-CoA synthase analogue, mupH in Pseudomonas fluorescens
Wu, J., Cooper, S. M., Cox, R. J., Crosby, J., Crump, M. P., Hothersall, J., Simpson, T. J., Thomas, C. M. & Willis, C. L., 1 Jan 2007, In: Chemical communications. 20, p. 2040-2042 3 p.Research output: Contribution to journal › Article › Research › peer review
Polyketides, proteins and genes in fungi: Programmed nano-machines begin to reveal their secrets
Cox, R. J., 1 Jan 2007, In: Organic and Biomolecular Chemistry. 5, 13, p. 2010-2026 17 p.Research output: Contribution to journal › Article › Research › peer review
Acyl palladium species in synthesis: Single-step synthesis of α,β-unsaturated ketones from acid chlorides
Cox, R. J. & Evitt, A. S., 2007, In: Organic and Biomolecular Chemistry. 5, 2, p. 229-232 4 p.Research output: Contribution to journal › Article › Research › peer review
Synthesis of [1,2-13C2,15N]-L-homoserine and its incorporation by the PKS-NRPS system of Fusarium moniliforme into the mycotoxin fusarin C
Rees, D. O., Bushby, N., Cox, R. J., Harding, J. R., Simpson, T. J. & Willis, C. L., 2007, In: CHEMBIOCHEM. 8, 1, p. 46-50 5 p.Research output: Contribution to journal › Article › Research › peer review
- 2006
Catalytic relationships between type I and type II iterative polyketide synthases: The Aspergillus parasiticus norsolorinic acid synthase
Ma, Y., Smith, L. H., Cox, R. J., Beltran-Alvarez, P., Arthur, C. J. & Simpson, T. J., 1 Dec 2006, In: CHEMBIOCHEM. 7, 12, p. 1951-1958 8 p.Research output: Contribution to journal › Article › Research › peer review
The Malonyl Transferase Activity of Type II Polyketide Synthase Acyl Carrier Proteins
Arthur, C. J., Szafranska, A. E., Long, J., Mills, J., Cox, R. J., Findlow, S. C., Simpson, T. J., Crump, M. P. & Crosby, J., 1 Jun 2006, In: Chemistry and Biology. 13, 6, p. 587-596 10 p.Research output: Contribution to journal › Article › Research › peer review
- 2005
Design, synthesis and analysis of inhibitors of bacterial aspartate semialdehyde dehydrogenase
Cox, R. J., Gibson, J. S. & Hadfield, A. T., 1 Dec 2005, In: CHEMBIOCHEM. 6, 12, p. 2255-2260 6 p.Research output: Contribution to journal › Article › Research › peer review
A fragment-based approach to understanding inhibition of 1-deoxy-D-xylulose-5-phosphate reductoisomerase
Mercklé, L., De Andrés-Gómez, A., Dick, B., Cox, R. J. & Godfrey, C. R. A., 1 Oct 2005, In: CHEMBIOCHEM. 6, 10, p. 1866-1874 9 p.Research output: Contribution to journal › Article › Research › peer review
Shift to Pseudomonic Acid B Production in P. fluorescens NCIMB10586 by Mutation of Mupirocin Tailoring Genes mupO, mupU, mupV, and macpE
Cooper, S. M., Laosripaiboon, W., Rahman, A. S., Hothersall, J., El-Sayed, A. K., Winfield, C., Crosby, J., Cox, R. J., Simpson, T. J. & Thomas, C. M., 1 Jul 2005, In: Chemistry and Biology. 12, 7, p. 825-833 9 p.Research output: Contribution to journal › Article › Research › peer review
Mupirocin W, a novel pseudomonic acid produced by targeted mutation of the mupirocin biosynthetic gene cluster
Cooper, S. M., Cox, R. J., Crosby, J., Crump, M. P., Hothersall, J., Laosripaiboon, W., Simpson, T. J. & Thomas, C. M., 7 Mar 2005, In: Chemical communications. 9, p. 1179-1181 3 p.Research output: Contribution to journal › Article › Research › peer review
Room temperature palladium catalysed coupling of acyl chlorides with terminal alkynes
Cox, R. J., Ritson, D. J., Dane, T. A., Berge, J., Charmant, J. P. H. & Kantacha, A., 28 Feb 2005, In: Chemical communications. 8, p. 1037-1039 3 p.Research output: Contribution to journal › Article › Research › peer review
- Published
Cloning fungal polyketide synthase genes: The fusarin and squalestatin synthases
Cox, R., 2005, In: ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.Research output: Contribution to journal › Article › Research › peer review
- 2004
Rapid cloning and expression of a fungal polyketide synthase gene involved in squalestatin biosynthesis
Cox, R. J., Glod, F., Hurley, D., Lazarus, C. M., Nicholson, T. P., Rudd, B. A. M., Simpson, T. J., Wilkinson, B. & Zhang, Y., 21 Oct 2004, In: Chemical communications. 20, p. 2260-2261 2 p.Research output: Contribution to journal › Article › Research › peer review
Fusarin C biosynthesis in Fusarium moniliforme and Fusarium venenatum
Song, Z., Cox, R. J., Lazarus, C. M. & Simpson, T. J., 6 Sept 2004, In: CHEMBIOCHEM. 5, 9, p. 1196-1203 8 p.Research output: Contribution to journal › Article › Research › peer review
Indium mediated allylation of glyoxylate oxime ethers, esters and cyanoformates
Ritson, D. J., Cox, R. J. & Berge, J., 7 Jul 2004, In: Organic and Biomolecular Chemistry. 2, 13, p. 1921-1933 13 p.Research output: Contribution to journal › Article › Research › peer review
Expression, purification and preliminary X-ray diffraction analysis of a ketoreductase from a type II polyketide synthase
Teartasin, W., Limpkin, C., Glod, F., Spencer, J., Cox, R. J., Simpson, T. J., Crosby, J., Crump, M. P. & Hadfield, A. T., 1 Jun 2004, In: Acta Crystallographica Section D: Biological Crystallography. 60, 6, p. 1137-1138 2 p.Research output: Contribution to journal › Article › Research › peer review
Efficient synthesis of protected cyclopropyl β-aspartylphosphates
Adams, L. A., Charmant, J. P. H., Cox, R. J., Walter, M. & Whittingham, W. G., 21 Feb 2004, In: Organic and Biomolecular Chemistry. 2, 4, p. 542-553 12 p.Research output: Contribution to journal › Article › Research › peer review