Publications
- 2014
Biosynthesis of thiomarinol A and related metabolites of Pseudoalteromonas sp. SANK 73390
Murphy, A. C., Gao, S. S., Han, L. C., Carobene, S., Fukuda, D., Song, Z., Hothersall, J., Cox, R. J., Crosby, J., Crump, M. P., Thomas, C. M., Willis, C. L. & Simpson, T. J., 1 Jan 2014, In: Chemical science. 5, 1, p. 397-402 6 p.Research output: Contribution to journal › Article › Research › peer review
Fungi as chemical industries and genetic engineering for the production of biologically active secondary metabolites
Khan, A. A., Bacha, N., Ahmad, B., Lutfullah, G., Farooq, U. & Cox, R. J., 1 Jan 2014, In: Asian Pacific Journal of Tropical Biomedicine. 4, 11, p. 859-870 12 p.Research output: Contribution to journal › Review article › Research › peer review
Phytochemicals from the aerial parts of Ligularia thomsonii and their radical scavenging activity
Hussain, S. H., Latif, A., Cox, R. J., Simpson, T. J., Ali, M., Arfan, M. & Uddin, G., 1 Jan 2014, In: Phytochemistry letters. 7, 1, p. 6-10 5 p.Research output: Contribution to journal › Article › Research › peer review
- 2013
A conserved motif flags acyl carrier proteins for β-branching in polyketide synthesis
Haines, A. S., Dong, X., Song, Z., Farmer, R., Williams, C., Hothersall, J., Płoskoń, E., Wattana-Amorn, P., Stephens, E. R., Yamada, E., Gurney, R., Takebayashi, Y., Masschelein, J., Cox, R. J., Lavigne, R., Willis, C. L., Simpson, T. J., Crosby, J., Winn, P. J., Thomas, C. M. & Crump, M. P., Nov 2013, In: Nature chemical biology. 9, 11, p. 685-692 8 p.Research output: Contribution to journal › Article › Research › peer review
Topical antiangiogenic SRPK1 inhibitors reduce choroidal neovascularization in rodent models of exudative AMD
Gammons, M. V., Fedorov, O., Ivison, D., Du, C., Clark, T., Hopkins, C., Hagiwara, M., Dick, A. D., Cox, R., Harper, S. J., Hancox, J. C., Knapp, S. & Bates, D. O., 13 Sept 2013, In: Investigative Ophthalmology and Visual Science. 54, 9, p. 6052-6062 11 p.Research output: Contribution to journal › Article › Research › peer review
- Published
One pathway, many compounds: Heterologous expression of a fungal biosynthetic pathway reveals its intrinsic potential for diversity
Wasil, Z., Pahirulzaman, K. A. K., Butts, C., Simpson, T. J., Lazarus, C. M. & Cox, R. J., 26 Aug 2013, In: Chemical science. 4, 10, p. 3845-3856 12 p.Research output: Contribution to journal › Article › Research › peer review
A new bezoxepin derivative from Senecio desfontainei
Hamid Hussain, S., Latif, A., Arfan, M., Ali, M., Simpson, T. J., Cox, R. J., Shaheen, F. & Uddin, G., 14 Aug 2013, In: Records of natural products. 7, 4, p. 325-331 7 p.Research output: Contribution to journal › Article › Research › peer review
- Published
Chemical mechanisms involved during the biosynthesis of tropolones
Cox, R. J. & Al-Fahad, A., 1 Aug 2013, In: Current Opinion in Chemical Biology. 17, 4, p. 532-536 5 p.Research output: Contribution to journal › Review article › Research › peer review
Isolation and Characterisation of a Ferrirhodin Synthetase Gene from the Sugarcane Pathogen Fusarium sacchari
Munawar, A., Marshall, J. W., Cox, R. J., Bailey, A. M. & Lazarus, C. M., 1 Feb 2013, In: CHEMBIOCHEM. 14, 3, p. 388-394 7 p.Research output: Contribution to journal › Article › Research › peer review
Phytochemicals from the stem wood of Sorbus lanata (D. Don.) Schauer
Uddin, G., Latif, A., Arfan, M., Ali, M., Hussain, S. H., Simpson, T. J., Cox, R. J. & Choudhary, M. I., 1 Feb 2013, In: Phytochemistry letters. 6, 1, p. 84-89 6 p.Research output: Contribution to journal › Article › Research › peer review
- Published
A conserved motif flags acyl carrier proteins for beta-branching in polyketide synthesis
Cox, R. J., 2013, In: Nature chemical biology.Research output: Contribution to journal › Article › Research › peer review
- 2012
Mechanism of metal-free hydrogen transfer between amine-boranes and aminoboranes
Leitao, E. M., Stubbs, N. E., Robertson, A. P. M., Helten, H., Cox, R. J., Lloyd-Jones, G. C. & Manners, I., 10 Oct 2012, In: Journal of the American Chemical Society. 134, 40, p. 16805-16816 12 p.Research output: Contribution to journal › Article › Research › peer review
Genetic, molecular, and biochemical basis of fungal tropolone biosynthesis
Davison, J., Al Fahad, A., Cai, M., Song, Z., Yehia, S. Y., Lazarus, C. M., Bailey, A. M., Simpson, T. J. & Cox, R. J., 15 May 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 20, p. 7642-7647 6 p.Research output: Contribution to journal › Article › Research › peer review
Polyketides in Fungi
Simpson, T. J. & Cox, R. J., 14 May 2012, Natural Products in Chemical Biology. John Wiley and Sons Inc., p. 143-161 19 p.Research output: Chapter in book/report/conference proceeding › Contribution to book/anthology › Research › peer review
- 2011
Rational domain swaps decipher programming in fungal highly reducing polyketide synthases and resurrect an extinct metabolite
Fisch, K. M., Bakeer, W., Yakasai, A. A., Song, Z., Pedrick, J., Wasil, Z., Bailey, A. M., Lazarus, C. M., Simpson, T. J. & Cox, R. J., 19 Oct 2011, In: Journal of the American Chemical Society. 133, 41, p. 16635-16641 7 p.Research output: Contribution to journal › Article › Research › peer review
Nongenetic reprogramming of a fungal highly reducing polyketide synthase
Yakasai, A. A., Davison, J., Wasil, Z., Halo, L. M., Butts, C. P., Lazarus, C. M., Bailey, A. M., Simpson, T. J. & Cox, R. J., 20 Jul 2011, In: Journal of the American Chemical Society. 133, 28, p. 10990-10998 9 p.Research output: Contribution to journal › Article › Research › peer review
Mupirocin F: Structure elucidation, synthesis and rearrangements
Scott, R. W., Murphy, A. C., Wu, J., Hothersall, J., Cox, R. J., Simpson, T. J., Thomas, C. M. & Willis, C. L., 8 Jul 2011, In: TETRAHEDRON. 67, 27-28, p. 5098-5106 9 p.Research output: Contribution to journal › Article › Research › peer review
The programming role of trans-acting enoyl reductases during the biosynthesis of highly reduced fungal polyketides
Heneghan, M. N., Yakasai, A. A., Williams, K., Kadir, K. A., Wasil, Z., Bakeer, W., Fisch, K. M., Bailey, A. M., Simpson, T. J., Cox, R. J. & Lazarus, C. M., 9 May 2011, In: Chemical science. 2, 5, p. 972-979 8 p.Research output: Contribution to journal › Article › Research › peer review
Manipulation of quorum sensing regulation in Pseudomonas fluorescens NCIMB 10586 to increase mupirocin production
Hothersall, J., Murphy, A. C., Iqbal, Z., Campbell, G., Stephens, E. R., Wu, J., Cooper, H., Atkinson, S., Williams, P., Crosby, J., Willis, C. L., Cox, R. J., Simpson, T. J. & Thomas, C. M., 1 May 2011, In: Applied Microbiology and Biotechnology. 90, 3, p. 1017-1026 10 p.Research output: Contribution to journal › Article › Research › peer review
Synthesis and evaluation of conformationally restricted inhibitors of aspartate semialdehyde dehydrogenase
Evitt, A. S. & Cox, R. J., 1 May 2011, In: Molecular BioSystems. 7, 5, p. 1564-1575 12 p.Research output: Contribution to journal › Article › Research › peer review