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Prof. Dr.  Philipp Heretsch

https://orcid.org/0000-0002-9967-3541
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Publications

  1. 2007

  2. Published

    An efficient entry to amino-substituted resorcylic acid derivatives for the synthesis of platensimycin and analogues

    Heretsch, P. & Giannis, A., 3 Sept 2007, In: SYNTHESIS-STUTTGART. 17, p. 2614-2616

    Research output: Contribution to journal › Article › Research › peer review

  3. 2008

  4. Published

    Syntheses with a chiral building block from the citric acid cycle: (2R,3S)-Isocitric acid by fermentation of sunflower oil

    Heretsch, P., Thomas, F., Aurich, A., Krautscheid, H., Sicker, D. & Giannis, A., 2008, In: Angewandte Chemie - International Edition. 47, 10, p. 1958-1960

    Research output: Contribution to journal › Article › Research › peer review

  5. 2009

  6. Published

    Synthesis of Cyclopamine Using a Biomimetic and Diastereoselective Approach

    Giannis, A., Heretsch, P., Sarli, V. & Stossel, A., 2009, In: Angewandte Chemie - International Edition. 48, 42, p. 7911-7914

    Research output: Contribution to journal › Article › Research › peer review

  7. Published

    Synthesis of All Diastereomers of the Piperidine-Alkaloid Substructure of Cyclopamine

    Heretsch, P., Rabe, S. & Giannis, A., 3 Dec 2009, In: Organic letters. 11, 23, p. 5410-5412

    Research output: Contribution to journal › Article › Research › peer review

  8. 2010

  9. Published

    Cyclopamine and Hedgehog Signaling: Chemistry, Biology, Medical Perspectives

    Heretsch, P., Tzagkaroulaki, L. & Giannis, A., 2010, In: Angewandte Chemie - International Edition. 49, 20, p. 3418-3427

    Research output: Contribution to journal › Review article › Research › peer review

  10. Published

    A Biomimetic Approach to C-nor-D-homo-Steroids

    Heretsch, P., Rabe, S. & Giannis, A., 28 Jul 2010, In: Journal of the American Chemical Society. 132, 29, p. 9968-9969

    Research output: Contribution to journal › Article › Research › peer review

  11. Published

    Modulators of the hedgehog signaling pathway

    Heretsch, P., Tzagkaroulaki, L. & Giannis, A., 15 Sept 2010, In: Bioorganic and Medicinal Chemistry. 18, 18, p. 6613-6624

    Research output: Contribution to journal › Review article › Research › peer review

  12. 2011

  13. Published

    Exo-Cyclopamine-a stable and potent inhibitor of hedgehog-signaling

    Heretsch, P., Buettner, A., Tzagkaroulaki, L., Zahn, S., Kirchner, B. & Giannis, A., 2011, In: Chemical communications. 47, 26, p. 7362-7364

    Research output: Contribution to journal › Article › Research › peer review

  14. Published

    Enantioselective Dichlorination of Allylic Alcohols

    Nicolaou, K. C., Simmons, N. L., Ying, Y., Heretsch, P. M. & Chen, J. S., 1 Jun 2011, In: Journal of the American Chemical Society. 133, 21, p. 8134-8137

    Research output: Contribution to journal › Article › Research › peer review

  15. 2012

  16. Published

    Microbiologically produced carboxylic acids used as building blocks in organic synthesis

    Aurich, A., Specht, R., Müller, R. A., Stottmeister, U., Yovkova, V., Otto, C., Holz, M., Barth, G., Heretsch, P., Thomas, F. A., Sicker, D. & Giannis, A., 2012, In: Subcellular Biochemistry. 64, p. 391-423 33 p.

    Research output: Contribution to journal › Review article › Research › peer review

  17. Published

    Synthesis and Biological Evaluation of Epidithio-, Epitetrathio-, and bis-(Methylthio)diketopiperazines: Synthetic Methodology, Enantioselective Total Synthesis of Epicoccin G, 8,8 '-epi-ent-Rostratin B, Gliotoxin, Gliotoxin G, Emethallicin E, and Haematocin and Discovery of New Antiviral and Antimalarial Agents

    Nicolaou, K. C., Lu, M., Totokotsopoulos, S., Heretsch, P., Giguere, D., Sun, Y., Sarlah, D., Nguyen, T. H., Wolf, I. C., Smee, D. F., Day, C. W., Bopp, S. & Winzeler, E. A., 17 Oct 2012, In: Journal of the American Chemical Society. 134, 41, p. 17320-17332

    Research output: Contribution to journal › Article › Research › peer review

  18. 2013

  19. Published

    General Synthetic Approach to Functionalized Dihydrooxepines

    Nicolaou, K. C., Yu, R., Shi, L., Cai, Q., Lu, M. & Heretsch, P., 19 Apr 2013, In: Organic letters. 15, 8, p. 1994-1997

    Research output: Contribution to journal › Article › Research › peer review

  20. Published

    Synthesis and antioxidant evaluation of (S,S)- and (R,R)-secoisolariciresinol diglucosides (SDGs)

    Mishra, O. P., Simmons, N., Tyagi, S., Pietrofesa, R., Shuvaev, V. V., Valiulin, R. A., Heretsch, P., Nicolaou, K. C. & Christofidou-Solomidou, M., 1 Oct 2013, In: Bioorganic and Medicinal Chemistry Letters. 23, 19, p. 5325-5328

    Research output: Contribution to journal › Article › Research › peer review

  21. Published

    Cyclopamine analogs bearing exocyclic methylenes are highly potent and acid-stable inhibitors of hedgehog signaling

    Moschner, J., Chentsova, A., Eilert, N., Rovardi, I., Heretsch, P. & Giannis, A., 31 Oct 2013, In: Beilstein Journal of Organic Chemistry. 9, p. 2328-2335

    Research output: Contribution to journal › Article › Research › peer review

  22. 2014

  23. External

    Cyclopamine and Congeners

    Heretsch, P. & Giannis, A., 19 May 2014, Natural Products in Medicinal Chemistry. Wiley-Blackwell, p. 545-564 20 p.

    Research output: Chapter in book/report/conference proceeding › Contribution to book/anthology › Research › peer review

  24. Published

    C-H-Functionalization logic guides the synthesis of a carbacyclopamine analog

    Rabe, S., Moschner, J., Bantzi, M., Heretsch, P. & Giannis, A., 9 Jul 2014, In: Beilstein Journal of Organic Chemistry. 10, p. 1564-1568

    Research output: Contribution to journal › Article › Research › peer review

  25. Published

    Total Synthesis of Delta(12)-Prostaglandin J(3), a Highly Potent and Selective Antileukemic Agent

    Nicolaou, K. C., Heretsch, P., ElMarrouni, A., Hale, C. R. H., Pulukuri, K. K., Kudva, A. K., Narayan, V. & Prabhu, K. S., 22 Sept 2014, In: Angewandte Chemie - International Edition. 53, 39, p. 10443-10447

    Research output: Contribution to journal › Article › Research › peer review

  26. Published

    Synthesis and Biological Evaluation of QRSTUVWXYZA ' Domains of Maitotoxin

    Nicolaou, K. C., Heretsch, P., Nakamura, T., Rudo, A., Murata, M. & Konoki, K., 19 Nov 2014, In: Journal of the American Chemical Society. 136, 46, p. 16444-16451

    Research output: Contribution to journal › Article › Research › peer review

  27. 2015

  28. Published

    The Veratrum and Solanum alkaloids

    Heretsch, P. & Giannis, A., 2015, In: The Alkaloids. Chemistry and biology. 74, p. 201-32 32 p.

    Research output: Contribution to journal › Review article › Research › peer review

  29. Published

    Total Synthesis of Trioxacarcin DC-45-A2

    Nicolaou, K. C., Cai, Q., Qin, B., Petersen, M. T., Mikkelsen, R. J. T. & Heretsch, P., 2 Mar 2015, In: Angewandte Chemie - International Edition. 54, 10, p. 3074-3078

    Research output: Contribution to journal › Article › Research › peer review

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