Publications
2010
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Synthesis and biological characterization of argyrin F (ChemMedChem (2010) 5, (832-836))
Bülow, L., Nickeleit, I., Girbig, A. K., Brodmann, T., Rentsch, A., Eggert, U., Sasse, F., Steinmetz, H., Frank, R., Carlomagno, T., Malek, N. P. & Kalesse, M., 7 Jun 2010, In: CHEMMEDCHEM. 5, 6, p. 805 1 p.Research output: Contribution to journal › Comment/debate › Research › peer review
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Elucidation of the structure and intermolecular interactions of a reversible cyclic-peptide inhibitor of the proteasome by NMR spectroscopy and molecular modeling
Stauch, B., Simon, B., Basile, T., Schneider, G., Malek, N. P., Kalesse, M. & Carlomagno, T., 25 May 2010, In: Angewandte Chemie - International Edition. 49, 23, p. 3934-3938 5 p.Research output: Contribution to journal › Article › Research › peer review
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Method for producing intermediates for the production of novel macrocycles that are inhibitors of the proteasomic degradation of p27, such as argyrin and derivatives thereof, and uses of said macrocycles
Eggert, U. (Inventor), Nisar, M. (Inventor), Girbig, A. (Inventor), Markus, K. (Inventor), Bulow, L. (Inventor), Frank, R. (Inventor), Ronald, F. (Inventor), Nisar, M. (Inventor), Andreas, R. (Inventor), Anna-Katharina, G. (Inventor), Leila, B. (Inventor), Ulrike, E. (Inventor), Tobias, B. (Inventor), Markus, K. (Inventor), Brodmann, T. (Inventor) & Rentsch, A. (Inventor), 21 Jan 2010, IPC No. A61K 38/ 04 A I, Patent No. AU2009270571, Priority date 23 Jun 2009, Priority No. WO2009EP04526Research output: Patent
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The oxygen-independent coproporphyrinogen III oxidase HemN utilizes harderoporphyrinogen as a reaction intermediate during conversion of coproporphyrinogen III to protoporphyrinogen IX
Rand, K., Noll, C., Schiebel, H. M., Kemken, D., Dülcks, T., Kalesse, M., Heinz, D. W. & Layer, G., 1 Jan 2010, In: Biological chemistry. 391, 1, p. 55-63 9 p.Research output: Contribution to journal › Article › Research › peer review
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Synthesis of symmetrical ureas by (Diacetoxyiodo)benzene-induced hofmann rearrangement
Landsberg, D. & Kalesse, M., 2010, In: SYNLETT. 7, p. 1104-1106 3 p.Research output: Contribution to journal › Article › Research › peer review
2009
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Enantioselective synthesis of polyketide segments through vinylogous Mukaiyama aldol reactions
Simsek, S. & Kalesse, M., 1 Jul 2009, In: Tetrahedron letters. 50, 26, p. 3485-3488 4 p.Research output: Contribution to journal › Article › Research › peer review
- External
The absolute configuration of rhizopodin and its inhibition of actin polymerization by dimerization
Hagelueken, G., Albrecht, S. C., Steinmetz, H., Jansen, R., Heinz, D. W., Kalesse, M. & Schubert, W. D., 5 Jan 2009, In: Angewandte Chemie - International Edition. 48, 3, p. 595-598 4 p.Research output: Contribution to journal › Article › Research › peer review
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Highly stereoselective aldol reactions in the total syntheses of complex natural products
Brodmann, T., Lorenz, M., Schäckel, R., Simsek, S. & Kalesse, M., Jan 2009, In: SYNLETT. 2, p. 174-192 19 p.Research output: Contribution to journal › Review article › Research › peer review
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Studies on the C22-C23 aldol coupling of spirangien
Lorenz, M., Bluhm, N. & Kalesse, M., 2009, In: Synthesis. 18, p. 3061-3066 6 p.Research output: Contribution to journal › Article › Research › peer review
2008
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Syntheses of the tedanolides and myriaporones
Schübel, N., Roy, M. & Kalesse, M., Nov 2008, In: Comptes Rendus Chimie (Print). 11, 11-12, p. 1419-1446 28 p.Research output: Contribution to journal › Survey paper › Research › peer review
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Chondramide C: Synthesis, configurational assignment, and structure-activity relationship studies
Eggert, U., Diestel, R., Sasse, F., Jansen, R., Kunze, B. & Kalesse, M., 11 Aug 2008, In: Angewandte Chemie - International Edition. 47, 34, p. 6478-6482 5 p.Research output: Contribution to journal › Article › Research › peer review
- External
Argyrin A Reveals a Critical Role for the Tumor Suppressor Protein p27kip1 in Mediating Antitumor Activities in Response to Proteasome Inhibition
Nickeleit, I., Zender, S., Sasse, F., Geffers, R., Brandes, G., Sörensen, I., Steinmetz, H., Kubicka, S., Carlomagno, T., Menche, D., Gütgemann, I., Buer, J., Gossler, A., Manns, M. P., Kalesse, M., Frank, R. & Malek, N. P., 8 Jul 2008, In: CANCER CELL. 14, 1, p. 23-35 13 p.Research output: Contribution to journal › Article › Research › peer review
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The total synthesis of (+)-tedanolide - A macrocyclic polyketide from marine sponge tedania ignis
Ehrlich, G., Hassfeld, J., Eggert, U. & Kalesse, M., 27 Feb 2008, In: Chemistry - a European journal. 14, 7, p. 2232-2247 16 p.Research output: Contribution to journal › Article › Research › peer review
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Interaction between importin 13 and myopodin suggests a nuclear import pathway for myopodin
Liang, J., Ke, G., You, W., Peng, Z., Lan, J., Kalesse, M., Tartakoff, A. M., Kaplan, F. & Tao, T., Jan 2008, In: Molecular and Cellular Biochemistry. 307, 1-2, p. 93-100 8 p.Research output: Contribution to journal › Article › Research › peer review
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Syntheses of the tedanolides
Roy, M. & Kalesse, M., 2008, In: Natural product reports. 25, 5, p. 862-870 9 p.Research output: Contribution to journal › Review article › Research › peer review
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Synthesis of the C10-C32 core structure of spirangien A
Lorenz, M. & Kalesse, M., 2008, In: Organic letters. 10, 19, p. 4371-4374 4 p.Research output: Contribution to journal › Article › Research › peer review
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The total synthesis of chlorotonil A
Rahn, N. & Kalesse, M., 2008, In: Angewandte Chemie - International Edition. 47, 3, p. 597-599 3 p.Research output: Contribution to journal › Article › Research › peer review
2007
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Oxazaborolidinone-promoted vinylogous mukaiyama aldol reactions
Simsek, S., Horzella, M. & Kalesse, M., 20 Dec 2007, In: Organic letters. 9, 26, p. 5637-5639 3 p.Research output: Contribution to journal › Article › Research › peer review
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Synthesis of the C15-C35 segment of chivosazole A
Janssen, D. & Kalesse, M., 16 Oct 2007, In: SYNLETT. 17, p. 2667-2670 4 p.Research output: Contribution to journal › Article › Research › peer review
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Synthesis of the C23-C32 fragment of spirangien
Lorenz, M. & Kalesse, M., 16 Apr 2007, In: Tetrahedron letters. 48, 16, p. 2905-2907 3 p.Research output: Contribution to journal › Article › Research › peer review
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Chivosazole A - Elucidation of the absolute and relative configuration
Janssen, D., Albert, D., Jansen, R., Müller, R. & Kalesse, M., 2007, In: Angewandte Chemie - International Edition. 46, 26, p. 4898-4901 4 p.Research output: Contribution to journal › Article › Research › peer review
2006
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The total synthesis of (+)-tedanolide
Ehrlich, G., Hassfeld, J., Eggert, U. & Kalesse, M., 1 Nov 2006, In: Journal of the American Chemical Society. 128, 43, p. 14038-14039 2 p.Research output: Contribution to journal › Article › Research › peer review
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Tandem intramolecular Michael-Aldol reaction as a tool for the construction of the C-ring of hexacyclinic acid
Stelmakh, A., Stellfeld, T. & Kalesse, M., 3 Aug 2006, In: Organic letters. 8, 16, p. 3485-3488 4 p.Research output: Contribution to journal › Article › Research › peer review
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Synthesis of the northern hemisphere of amphidinolide H2
Liesener, F. P., Jannsen, U. & Kalesse, M., 1 Aug 2006, In: Synthesis. 15, p. 2590-2602 13 p.Research output: Contribution to journal › Article › Research › peer review
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TAR-RNA recognition by a novel cyclic aminoglycoside analogue
Raghunathan, D., Sánchez-Pedregal, V. M., Junker, J., Schwiegk, C., Kalesse, M., Kirschning, A. & Carlomagno, T., 1 Jan 2006, In: Nucleic Acids Research. 34, 12, p. 3599-3608 10 p.Research output: Contribution to journal › Article › Research › peer review
2005
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Synthesis of the C19-C26 segment of amphidinolide H2
Liesener, F. P. & Kalesse, M., 2 Sept 2005, In: SYNLETT. 14, p. 2236-2238 3 p.Research output: Contribution to journal › Article › Research › peer review
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Asymmetric total synthesis of complex marine natural products
Hassfeld, J., Kalesse, M., Stellfeld, T. & Christmann, M., 8 Aug 2005, Marine Biotechnology II. Ulber, R. & Le Gal, Y. (eds.). p. 133-203 71 p. (Advances in Biochemical Engineering/Biotechnology; vol. 97).Research output: Chapter in book/report/conference proceeding › Contribution to book/anthology › Research › peer review
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Synthesis of the C1-C17 macrolactone of tedanolide
Hassfeld, J., Eggert, U. & Kalesse, M., 2 May 2005, In: Synthesis. 7, p. 1183-1199 17 p.Research output: Contribution to journal › Review article › Research › peer review
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A one-pot non-aldol-aldol vinylogous Mukaiyama aldol tandem sequence for the rapid construction of polyketide frameworks
Rahn, N. & Kalesse, M., 21 Mar 2005, In: SYNLETT. 5, p. 863-865 3 p.Research output: Contribution to journal › Article › Research › peer review
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Synthesis of the C13-C23 segment of tedanolide
Ehrlich, G. & Kalesse, M., 4 Mar 2005, In: SYNLETT. 4, p. 655-657 3 p.Research output: Contribution to journal › Article › Research › peer review
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Recent advances in vinylogous aldol reactions and their applications in the syntheses of natural products
Kalesse, M., 26 Jan 2005, Natural Product Synthesis II: Targets, Methods, Concepts. Mulzer, J. (ed.). p. 43-76 34 p. (Topics in Current Chemistry; vol. 244).Research output: Chapter in book/report/conference proceeding › Contribution to book/anthology › Research › peer review
2004
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Synthesis of the A,B,C-ring system of hexacyclinic acid
Stellfeld, T., Bhatt, U. & Kalesse, M., 28 Oct 2004, In: Organic letters. 6, 22, p. 3889-3892 4 p.Research output: Contribution to journal › Article › Research › peer review
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Synthesis of extended spacer-linked neooligodeoxysaccharides by metathesis olefination and evaluation of their RNA-binding properties
Kirschning, A., Chen, G. W., Jaunzems, J., Jesberger, M., Kalesse, M. & Lindner, M., 17 Mar 2004, In: Tetrahedron. 60, 15, p. 3505-3521 17 p.Research output: Contribution to journal › Article › Research › peer review
2003
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Multi parameter in vitro testing of ratjadone using flow cytometry
Burzlaff, A., Kalesse, M., Kasper, C. & Scheper, T., 4 Apr 2003, In: Applied Microbiology and Biotechnology. 62, 2-3, p. 174-179 6 p.Research output: Contribution to journal › Article › Research › peer review
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The Total Synthesis of (-)-Callystatin A
Kalesse, M., Chary, K. P., Quitschalle, M., Burzlaff, A., Kasper, C. & Scheper, T., 21 Feb 2003, In: Chemistry - a European journal. 9, 5, p. 1129-1136 8 p.Research output: Contribution to journal › Article › Research › peer review
2002
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RATJADON-DERIVATE ZUM HEMMEN DES ZELLWACHSTUMS
Burzlaff, A. (Inventor), Kasper, C. (Inventor), Scheper, T. (Inventor), Kalesse, M. (Inventor), Bhatt, U. (Inventor), Chary, K. (Inventor), Claus, E. (Inventor), Christmann, M. (Inventor), Quitschalle, M. (Inventor) & Beil, W. (Inventor), 22 Aug 2002, IPC No. C07D309/32A I, A61P31/04, A61P35/00, C07D309/06 , C07D309/10, C07D309/32 , A61K31/365 , A61P31/04 , C07D407/06, Patent No. WO02064587A1, 26 Jan 2002, Priority date 12 Feb 2001, Priority No. DE20011006647Research output: Patent
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Advances in the vinylogous Mukaiyama aldol reaction and its application to the synthesis of the C1-C7 subunit of oleandolide
Hassfeld, J. & Kalesse, M., 15 Jul 2002, In: Tetrahedron letters. 43, 29, p. 5093-5095 3 p.Research output: Contribution to journal › Article › Research › peer review
- External
Synthesis of the C1-C11 segment of tedanolide via vinylogous Mukaiyama aldol reaction
Hassfeld, J. & Kalesse, M., 2002, In: SYNLETT. 12, p. 2007-2010 4 p.Research output: Contribution to journal › Article › Research › peer review
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The chemistry and biology of the leptomycin family
Kalesse, M. & Christmann, M., 2002, In: Synthesis. 8, p. 981-1003 23 p.Research output: Contribution to journal › Review article › Research › peer review
2001
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Rapid access to polyketide scaffolds via vinylogous Mukaiyama aldol reactions
Hassfeld, J., Christmann, M. & Kalesse, M., 1 Nov 2001, In: Organic letters. 3, 22, p. 3561-3564 4 p.Research output: Contribution to journal › Article › Research › peer review
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Total synthesis of (-)-callystatin A
Kalesse, M., Quitschalle, M., Khandavalli, C. P. & Saeed, A., 4 Oct 2001, In: Organic letters. 3, 20, p. 3107-3109 3 p.Research output: Contribution to journal › Article › Research › peer review
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The Chemstry and Biology of Ratjadone
Kalesse, M., Christmann, M., Bhatt, U., Quitschalle, M., Claus, E., Saeed, A., Burzlaff, A., Kasper, C., Haustedt, L. O., Hofer, E., Scheper, T. & Beil, W., 10 Sept 2001, In: CHEMBIOCHEM. 2, 9, p. 709-714 6 p.Research output: Contribution to journal › Article › Research › peer review
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The first total synthesis of (+)-ratjadone
Bhatt, U., Christmann, M., Quitschalle, M., Claus, E. & Kalesse, M., 9 Mar 2001, In: Journal of Organic Chemistry. 66, 5, p. 1885-1893 9 p.Research output: Contribution to journal › Article › Research › peer review
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Synthesis of unsaturated lactone moieties by asymmetric hetero Diels-Alder reactions with binaphthol-titanium complexes
Quitschalle, M., Christmann, M., Bhatt, U. & Kalesse, M., 12 Feb 2001, In: Tetrahedron letters. 42, 7, p. 1263-1265 3 p.Research output: Contribution to journal › Article › Research › peer review
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Vinylogous Mukaiyama aldol reactions with triarylboranes
Christmann, M. & Kalesse, M., 12 Feb 2001, In: Tetrahedron letters. 42, 7, p. 1269-1271 3 p.Research output: Contribution to journal › Article › Research › peer review
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In Vitro Testing of a New Substance with Anti-Tumor Activity on Mammalian Cells Using Flow Cytometry
Burzlaff, A., Kasper, C., Christmann, M., Bhatt, U., Kalesse, M. & Scheper, T., 2001, Animal Cell Technology: From Target to Market. (ESACT Proceedings; vol. 1).Research output: Chapter in book/report/conference proceeding › Conference contribution › Research
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Selective cleavage of unpaired uridines with a tyrosine-cyclen conjugate
Kalesse, M., 2001, In: CHEMBIOCHEM. 2, 1, p. 79-83 5 p.Research output: Contribution to journal › Article › Research › peer review
2000
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Total synthesis of (+)-ratjadone
Christmann, M., Bhatt, U., Quitschalle, M., Claus, E. & Kalesse, M., 4 Dec 2000, In: Angewandte Chemie - International Edition. 39, 23, p. 4364-4366 3 p.Research output: Contribution to journal › Article › Research › peer review
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The chemistry and biology of discodermolide
Kalesse, M., 2 Oct 2000, In: Angewandte Chemie International Edition. 39, 19 SUPPL., p. 171-175 5 p.Research output: Contribution to journal › Review article › Research › peer review
1999
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The formal total synthesis of epothilone A
Kalesse, M., Quitschalle, M., Claus, E., Gerlach, K., Pahl, A. & Meyer, H. H., Nov 1999, In: European Journal of Organic Chemistry. 11, p. 2817-2823 7 p.Research output: Contribution to journal › Article › Research › peer review
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Improved synthesis of the northern hemisphere of epothilone A by a sharpless asymmetric dihydroxylation
Quitschalle, M. & Kalesse, M., 29 Oct 1999, In: Tetrahedron letters. 40, 44, p. 7765-7768 4 p.Research output: Contribution to journal › Article › Research › peer review
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The synthesis of the C15-C24 segment of ratjadone
Christmann, M. & Kalesse, M., 1 Oct 1999, In: Tetrahedron letters. 40, 40, p. 7201-7204 4 p.Research output: Contribution to journal › Article › Research › peer review
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Selective cleavage of the HIV-1 TAR-RNA with a peptide-cyclen conjugate
Michaelis, K. & Kalesse, M., 28 Jul 1999, In: Angewandte Chemie - International Edition. 38, 15, p. 2243-2245 3 p.Research output: Contribution to journal › Article › Research › peer review
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Synthesis of the C6-C16 polyene fragment of ratjadone, a potent cytotoxic metabolite from Sorangium cellulosum
Claus, E. & Kalesse, M., 28 May 1999, In: Tetrahedron letters. 40, 22, p. 4157-4160 4 p.Research output: Contribution to journal › Article › Research › peer review
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Synthesis of the northern hemisphere of epothilone A by a ten-membered ring closing metathesis reaction
Gerlach, K., Quitschalle, M. & Kalesse, M., 30 Apr 1999, In: Tetrahedron letters. 40, 18, p. 3553-3556 4 p.Research output: Contribution to journal › Article › Research › peer review
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Synthesis of RNAse active site model systems using a steroid template
Kalesse, M. & Oost, T., 1999, In: Polish Journal of Chemistry. 73, 1, p. 89-99 11 p.Research output: Contribution to journal › Article › Research › peer review
1998
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Synthesis of the C7-C17 segment of epothilones by a 10-membered ring closing metathesis reaction
Gerlach, K., Quitschalle, M. & Kalesse, M., Oct 1998, In: SYNLETT. 10, p. 1108-1110 3 p.Research output: Contribution to journal › Article › Research › peer review
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Structural features for the promotion of optimal stacking in the solid state
Kalesse, M. & Wartchow, R., 9 Jul 1998, In: TETRAHEDRON. 54, 28, p. 8015-8024 10 p.Research output: Contribution to journal › Article › Research › peer review
1997
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Synthesis of RNAse active site model systems using a steroid template
Oost, T. & Kalesse, M., 23 Jun 1997, In: TETRAHEDRON. 53, 25, p. 8421-8438 18 p.Research output: Contribution to journal › Article › Research › peer review
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Bis(guanidinium) receptors as ribonuclease active-site model systems: Structural changes and solvent effects
Oost, T., Filippazzi, A. & Kalesse, M., May 1997, In: Liebigs Annales. 5, p. 1005-1011 7 p.Research output: Contribution to journal › Article › Research › peer review
- External
Synthesis of the C1-C9 segment of epothilons
Claus, E., Pahl, A., Jones, P. G., Meyer, H. M. & Kalesse, M., 24 Feb 1997, In: Tetrahedron letters. 38, 8, p. 1359-1362 4 p.Research output: Contribution to journal › Article › Research › peer review
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Generation of thiazoles by column dehydrogenation of thiazolidines with MnO2
Mensching, S. & Kalesse, M., 1997, In: Journal fur Praktische Chemie - Chemiker - Zeitung. 339, 1, p. 96-97 2 p.Research output: Contribution to journal › Article › Research › peer review
1996
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Remarkable hydrolysis of phosphodiester by neutral lanthanide(III) DO3A complexes
Kalesse, M. & Loos, A., 3 Sept 1996, In: Bioorganic and Medicinal Chemistry Letters. 6, 17, p. 2063-2068 6 p.Research output: Contribution to journal › Article › Research › peer review
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Transesterification of phosphodiester by a zinc-containing cyclen derivative: Identification of the active species
Kalesse, M. & Loos, A., Jun 1996, In: Liebigs Annales. 6, p. 935-939 5 p.Research output: Contribution to journal › Article › Research › peer review
1995
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An efficient synthesis of radicinin analogues
Eh, M., Schomburg, D., Schicht, K. & Kalesse, M., 14 Aug 1995, In: TETRAHEDRON. 51, 33, p. 8983-8992 10 p.Research output: Contribution to journal › Article › Research › peer review
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Remarkable kinetic resolution of chiral β-keto esters by baker's yeast reduction
Eh, M. & Kalesse, M., Aug 1995, In: SYNLETT. 1995, 8, p. 837-838 2 p.Research output: Contribution to journal › Article › Research › peer review
1991
- External
Diastereoselective double michael additions of vinylogous esters and thexyldimethylsilyl triflate-induced cyclizations
Schinzer, D. & Kalesse, M., 1991, In: Tetrahedron letters. 32, 36, p. 4691-4694 4 p.Research output: Contribution to journal › Article › Research › peer review
1989
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Silica gel catalyzed cyclizations of enones and double michael additions of vinylogous amides: Efficient synthesis of bicyclo[2.2.2]octanones and bicyclo-hydrocarbazolones
Schinzer, D. & Kalesse, M., Sept 1989, In: SYNLETT. 1989, 1, p. 34-35 2 p.Research output: Contribution to journal › Article › Research › peer review
1988
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Silica gel-catalyzed cyclizations of mixed ketene acetals
Schinzer, D., Kalesse, M. & Kabbara, J., 1988, In: Tetrahedron letters. 29, 41, p. 5241-5244 4 p.Research output: Contribution to journal › Article › Research › peer review