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Publications

  1. 2024
  2. Published

    A Novel 3D-Printed and Miniaturized Periodic Counter Current Chromatography System for Continuous Purification of Monoclonal Antibodies

    Kortmann, C., Habib, T., Heuer, C., Solle, D. & Bahnemann, J., 13 Mar 2024, In: Micromachines. 15, 3, 17 p., 382.

    Research output: Contribution to journalArticleResearchpeer review

  3. 2023
  4. Published

    Establishment of a Perfusion Process with Antibody-Producing CHO Cells Using a 3D-Printed Microfluidic Spiral Separator with Web-Based Flow Control

    Schellenberg, J., Dehne, M., Lange, F., Scheper, T., Solle, D. & Bahnemann, J., Jun 2023, In: Bioengineering. 10, 6, 656.

    Research output: Contribution to journalArticleResearchpeer review

  5. Published

    3D-Druck zur Miniaturisierung von chromatographischen Anwendungen

    Kortmann, C., Habib, T., Solle, D. & Bahnemann, J., 31 May 2023, In: BioSpektrum. 29, 3, p. 276-277 2 p.

    Research output: Contribution to journalArticleResearchpeer review

  6. Published

    Digitale Zwillinge in der Bioprozesstechnik – Chancen und Möglichkeiten

    RIchter, J., Lange, F., Scheper, T., Solle, D. & Beutel, S., 22 Mar 2023, In: Chemie-Ingenieur-Technik. 95, 4, p. 498-510 13 p.

    Research output: Contribution to journalArticleResearch

  7. Published

    Employing QbD strategies to assess the impact of cell viability and density on the primary recovery of monoclonal antibodies

    Wohlenberg, O. J., Kortmann, C., Meyer, K. V., Scheper, T. & Solle, D., 2 Feb 2023, In: Engineering in life sciences. 23, 2, e202200056.

    Research output: Contribution to journalArticleResearchpeer review

  8. 2022
  9. Published

    Optimization of a mAb production process with regard to robustness and product quality using quality by design principles

    Wohlenberg, O. J., Kortmann, C., Meyer, K. V., Schellenberg, J., Dahlmann, K., Bahnemann, J., Scheper, T. & Solle, D., Jul 2022, In: Engineering in life sciences. 22, 7, p. 484-494 11 p.

    Research output: Contribution to journalArticleResearchpeer review

  10. Published

    Stress-induced increase of monoclonal antibody production in CHO cells

    Schellenberg, J., Nagraik, T., Wohlenberg, O. J., Ruhl, S., Bahnemann, J., Scheper, T. & Solle, D., May 2022, In: Engineering in life sciences. 22, 5, p. 427-436 10 p.

    Research output: Contribution to journalArticleResearchpeer review

  11. 2021
  12. Published

    Monitoring cell productivity for the production of recombinant proteins by flow cytometry: An effective application using the cold capture assay

    Meyer, K. V., Siller, I. G., Schellenberg, J., Gonzalez Salcedo, A., Solle, D., Matuszczyk, J., Scheper, T. & Bahnemann, J., May 2021, In: Engineering in life sciences. 21, 5, p. 288-293 6 p.

    Research output: Contribution to journalArticleResearchpeer review

  13. Published

    Disposable flowcell for spectroscopic analysis in bioprocesses

    Raithel, P., Steinwedel, T., Belz, M. & Solle, D., 5 Mar 2021, Optical Fibers and Sensors for Medical Diagnostics, Treatment and Environmental Applications XXI. Gannot, I. & Roodenko, K. (eds.). Bellingham: SPIE, 8 p. 1163514. (Proceedings of SPIE; vol. 11635)(Progress in biomedical optics and imaging; vol. 22, no. 27).

    Research output: Chapter in book/report/conference proceedingConference contributionResearchpeer review

  14. Published

    Implementation of QbD strategies in the inoculum expansion of a mAb production process

    Böhl, O. J., Schellenberg, J., Bahnemann, J., Hitzmann, B., Scheper, T. & Solle, D., 2 Mar 2021, In: Engineering in life sciences. 21, 3-4, p. 196-207 12 p.

    Research output: Contribution to journalArticleResearchpeer review

  15. 2020
  16. Published

    Development and characterization of a fiber optical fluorescence sensor for the online monitoring of biofilms and their microenvironment

    Schlaugat, J., Patzer, K., Hentrop, T., Solle, D., Pepelanova, I., Schröder, U. & Scheper, T., 6 Jul 2020, In: Engineering in life sciences. 20, 7, p. 252-264 13 p.

    Research output: Contribution to journalArticleResearchpeer review

  17. Published

    Be FAIR to your data

    Solle, D., Jul 2020, In: Analytical and Bioanalytical Chemistry. 412, 17, p. 3961-3965 5 p.

    Research output: Contribution to journalArticleResearchpeer review

  18. Published

    Process optimization using high throughput automated micro-bioreactors in chinese hamster ovary cell cultivation

    Nagraik, T., Salcedo, A. G., Solle, D. & Scheper, T., 18 May 2020, In: Journal of visualized experiments. 2020, 159, e60577.

    Research output: Contribution to journalArticleResearchpeer review

  19. 2019
  20. Published

    Online monitoring of the cell-specific oxygen uptake rate with an in situ combi-sensor

    Dahlmann, K., Busse, C., Aupert, F., de Vries, I., Marquard, D., Solle, D., Lammers, F. & Scheper, T., 4 Dec 2019, In: Analytical and Bioanalytical Chemistry. 412, 9, p. 2111-2121 11 p.

    Research output: Contribution to journalArticleResearchpeer review

  21. Published

    Membrane Adsorber for the Fast Purification of a Monoclonal Antibody Using Protein A Chromatography

    Brämer, C., Tünnermann, L., Salcedo, A. G., Reif, O. W., Solle, D., Scheper, T. & Beutel, S., Dec 2019, In: Membranes. 9, 12, 159.

    Research output: Contribution to journalArticleResearchpeer review

  22. Published

    High cell density transient transfection of CHO cells for TGF-β1 expression

    Elshereef, A. A., Jochums, A., Lavrentieva, A., Stuckenberg, L., Scheper, T. & Solle, D., 4 Nov 2019, In: Engineering in life sciences. 19, 11, p. 730-740 11 p.

    Research output: Contribution to journalArticleResearchpeer review

  23. Published

    Sensors for disposable bioreactor systems

    Steinwedel, T., Dahlmann, K., Solle, D., Scheper, T., Reardon, K. F. & Lammers, F., 5 Aug 2019, Single-Use Technology in Biopharmaceutical Manufacture. Eibl, R. & Eibl, D. (eds.). 2. ed. Wiley-Blackwell, p. 69-82 14 p.

    Research output: Chapter in book/report/conference proceedingContribution to book/anthologyResearchpeer review

  24. Published

    A novel LED-based 2D-fluorescence spectroscopy system for in-line bioprocess monitoring of Chinese hamster ovary cell cultivations—Part II

    Claßen, J., Graf, A., Aupert, F., Solle, D., Höhse, M. & Scheper, T., 6 May 2019, In: Engineering in life sciences. 19, 5, p. 341-351 11 p.

    Research output: Contribution to journalArticleResearchpeer review

  25. Published

    A novel LED-based 2D-fluorescence spectroscopy system for in-line monitoring of Chinese hamster ovary cell cultivations – Part I

    Graf, A., Claßen, J., Solle, D., Hitzmann, B., Rebner, K. & Hoehse, M., 6 May 2019, In: Engineering in life sciences. 19, 5, p. 352-362 11 p.

    Research output: Contribution to journalArticleResearchpeer review

  26. Published

    Impact of stress on the productivity in mammalian cells

    Schellenberg, J., Nagraik, T., Bahnemann, J., Solle, D. & Scheper, T., 2019.

    Research output: Contribution to conferencePosterResearch

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