Details
| Original language | English |
|---|---|
| Pages (from-to) | 5656-5669 |
| Number of pages | 14 |
| Journal | Biomedical optics express |
| Volume | 14 |
| Issue number | 11 |
| Early online date | 9 Oct 2023 |
| Publication status | Published - 1 Nov 2023 |
Abstract
The use of ultrashort pulse lasers in medical treatments is increasing and is already an essential tool, particularly in the treatment of eyes, bones and skin. One of the main advantages of laser treatment is that it is fast and minimally invasive. Due to the interaction of ultrashort laser pulses with matter, X-rays can be generated during the laser ablation process. This is important not only for the safety of the patient, but also for the practitioner to ensure that the legally permissible dose is not exceeded. Although our results do not raise safety concerns for existing clinical applications, they might impact future developments at higher peak powers. In order to provide guidance to laser users in the medical field, this paper examines the X-ray emission spectra and dose of several biological materials and describes their dependence on the laser pulse energy.
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Biotechnology
- Physics and Astronomy(all)
- Atomic and Molecular Physics, and Optics
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In: Biomedical optics express, Vol. 14, No. 11, 01.11.2023, p. 5656-5669.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - X-ray generation by fs-laser processing of biological material
AU - Mosel, P.
AU - Düsing, J.
AU - Johannesmeier, S.
AU - Patzlaff-Günther, M.
AU - Fröhlich, S.
AU - Mapa, J.
AU - Kalies, S.
AU - Bahlmann, J.
AU - Püster, T.
AU - Vahlbruch, J.
AU - Dittmar, G.
AU - Merdji, H.
AU - Fajardo, M.
AU - Trabattoni, A.
AU - Heisterkamp, A.
AU - Morgner, U.
AU - Kovacev, M.
N1 - Funding Information: HORIZON EUROPE European Innovation Council (101047223-NanoXCAN); Deutsche Forschungsgemeinschaft (PhoenixD (EXC 2122, Project ID 390833453)), Quantum Frontiers (EXC-2123 Quantum Frontiers - 390837967)). The publication of this article was funded by the Open Access Fund of the Leibniz Universität Hannover.
PY - 2023/11/1
Y1 - 2023/11/1
N2 - The use of ultrashort pulse lasers in medical treatments is increasing and is already an essential tool, particularly in the treatment of eyes, bones and skin. One of the main advantages of laser treatment is that it is fast and minimally invasive. Due to the interaction of ultrashort laser pulses with matter, X-rays can be generated during the laser ablation process. This is important not only for the safety of the patient, but also for the practitioner to ensure that the legally permissible dose is not exceeded. Although our results do not raise safety concerns for existing clinical applications, they might impact future developments at higher peak powers. In order to provide guidance to laser users in the medical field, this paper examines the X-ray emission spectra and dose of several biological materials and describes their dependence on the laser pulse energy.
AB - The use of ultrashort pulse lasers in medical treatments is increasing and is already an essential tool, particularly in the treatment of eyes, bones and skin. One of the main advantages of laser treatment is that it is fast and minimally invasive. Due to the interaction of ultrashort laser pulses with matter, X-rays can be generated during the laser ablation process. This is important not only for the safety of the patient, but also for the practitioner to ensure that the legally permissible dose is not exceeded. Although our results do not raise safety concerns for existing clinical applications, they might impact future developments at higher peak powers. In order to provide guidance to laser users in the medical field, this paper examines the X-ray emission spectra and dose of several biological materials and describes their dependence on the laser pulse energy.
UR - http://www.scopus.com/inward/record.url?scp=85176262082&partnerID=8YFLogxK
U2 - 10.1364/BOE.499170
DO - 10.1364/BOE.499170
M3 - Article
AN - SCOPUS:85176262082
VL - 14
SP - 5656
EP - 5669
JO - Biomedical optics express
JF - Biomedical optics express
SN - 2156-7085
IS - 11
ER -