Details
| Original language | English |
|---|---|
| Pages (from-to) | 419-436 |
| Number of pages | 18 |
| Journal | Annual Review of Phytopathology |
| Volume | 48 |
| Publication status | Published - 8 Sept 2010 |
| Externally published | Yes |
Abstract
Xanthomonads are bacterial plant pathogens that cause diseases on many plant species, including important crops. Key to pathogenicity of most Xanthomonas pathovars is a Hrp-type III secretion (T3S) system that translocates effector proteins into plant cells. Within the eukaryotic cell, the effectors are thought to perform a variety of tasks to support bacterial virulence, proliferation, and dissemination. We are only beginning to understand the host targets of different effectors. The largest effector family found in Xanthomonas spp. is the AvrBs3/PthA or TAL (transcription activator-like) family. TAL effectors act as transcriptional activators in the plant cell nucleus. Specificity of TAL effectors is determined by a novel modular DNA-binding domain. Here, we describe the discovery of TAL effectors and their structure, activity, and host targets.
Keywords
- biotechnology, DNA-binding motif, plant pathogen, T3S, TAL, transcription factor
ASJC Scopus subject areas
- Agricultural and Biological Sciences(all)
- Plant Science
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In: Annual Review of Phytopathology, Vol. 48, 08.09.2010, p. 419-436.
Research output: Contribution to journal › Review article › Research › peer review
}
TY - JOUR
T1 - Xanthomonas AvrBs3 family-type III effectors: discovery and function
AU - Boch, Jens
AU - Bonas, Ulla
N1 - Copyright: Copyright 2011 Elsevier B.V., All rights reserved.
PY - 2010/9/8
Y1 - 2010/9/8
N2 - Xanthomonads are bacterial plant pathogens that cause diseases on many plant species, including important crops. Key to pathogenicity of most Xanthomonas pathovars is a Hrp-type III secretion (T3S) system that translocates effector proteins into plant cells. Within the eukaryotic cell, the effectors are thought to perform a variety of tasks to support bacterial virulence, proliferation, and dissemination. We are only beginning to understand the host targets of different effectors. The largest effector family found in Xanthomonas spp. is the AvrBs3/PthA or TAL (transcription activator-like) family. TAL effectors act as transcriptional activators in the plant cell nucleus. Specificity of TAL effectors is determined by a novel modular DNA-binding domain. Here, we describe the discovery of TAL effectors and their structure, activity, and host targets.
AB - Xanthomonads are bacterial plant pathogens that cause diseases on many plant species, including important crops. Key to pathogenicity of most Xanthomonas pathovars is a Hrp-type III secretion (T3S) system that translocates effector proteins into plant cells. Within the eukaryotic cell, the effectors are thought to perform a variety of tasks to support bacterial virulence, proliferation, and dissemination. We are only beginning to understand the host targets of different effectors. The largest effector family found in Xanthomonas spp. is the AvrBs3/PthA or TAL (transcription activator-like) family. TAL effectors act as transcriptional activators in the plant cell nucleus. Specificity of TAL effectors is determined by a novel modular DNA-binding domain. Here, we describe the discovery of TAL effectors and their structure, activity, and host targets.
KW - biotechnology
KW - DNA-binding motif
KW - plant pathogen
KW - T3S
KW - TAL
KW - transcription factor
UR - http://www.scopus.com/inward/record.url?scp=77956126894&partnerID=8YFLogxK
U2 - 10.1146/annurev-phyto-080508-081936
DO - 10.1146/annurev-phyto-080508-081936
M3 - Review article
C2 - 19400638
AN - SCOPUS:77956126894
VL - 48
SP - 419
EP - 436
JO - Annual Review of Phytopathology
JF - Annual Review of Phytopathology
SN - 0066-4286
ER -