Details
| Original language | English |
|---|---|
| Pages (from-to) | 19892-19900 |
| Number of pages | 9 |
| Journal | Physical Chemistry Chemical Physics |
| Volume | 23 |
| Issue number | 35 |
| Early online date | 30 Aug 2021 |
| Publication status | Published - 21 Sept 2021 |
| Externally published | Yes |
Abstract
Two prototropic isomers of adenine are formed in an electrospray ion source and are resolved spatially in a differential mobility spectrometer before detection in a triple quadrupole mass spectrometer. Each isomer is gated in CV space before being trapped in the linear ion trap of the modified mass spectrometer, where they are irradiated by the tuneable output of an optical parametric oscillator and undergo photodissociation to form charged fragments withm/z119, 109, and 94. The photon-normalised intensity of each fragmentation channel is measured and the action spectra for each DMS-gated tautomer are obtained. Our analysis of the action spectra, aided by calculated vibronic spectra and thermochemical data, allow us to assign the two signals in our measured ionograms to specific tautomers of protonated adenine.
ASJC Scopus subject areas
- Physics and Astronomy(all)
- General Physics and Astronomy
- Chemistry(all)
- Physical and Theoretical Chemistry
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In: Physical Chemistry Chemical Physics, Vol. 23, No. 35, 21.09.2021, p. 19892-19900.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - UVPD spectroscopy of differential mobility-selected prototropic isomers of protonated adenine
AU - Heldmaier, Fiorella Villanueva
AU - Coughlan, Neville J.A.
AU - Haack, Alexander
AU - Huard, Rebecca
AU - Guna, Mircea
AU - Schneider, Bradley B.
AU - Le Blanc, J. C.Y.
AU - Campbell, J. Larry
AU - Nooijen, Marcel
AU - Hopkins, W. Scott
N1 - Funding Information: WSH acknowledges NSERC funding in the form of a Discovery Grant, a Collaborative Research and Development grant, and Alliance Grant, funding from the Mitacs Accelerate program, and support from Compute Canada. NJAC acknowledges NSERC funding in the form of a Vanier-Banting postdoctoral fellowship. AH acknowledges his contribution being funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) – 449651261. MN is supported by an NSERC discovery grant.
PY - 2021/9/21
Y1 - 2021/9/21
N2 - Two prototropic isomers of adenine are formed in an electrospray ion source and are resolved spatially in a differential mobility spectrometer before detection in a triple quadrupole mass spectrometer. Each isomer is gated in CV space before being trapped in the linear ion trap of the modified mass spectrometer, where they are irradiated by the tuneable output of an optical parametric oscillator and undergo photodissociation to form charged fragments withm/z119, 109, and 94. The photon-normalised intensity of each fragmentation channel is measured and the action spectra for each DMS-gated tautomer are obtained. Our analysis of the action spectra, aided by calculated vibronic spectra and thermochemical data, allow us to assign the two signals in our measured ionograms to specific tautomers of protonated adenine.
AB - Two prototropic isomers of adenine are formed in an electrospray ion source and are resolved spatially in a differential mobility spectrometer before detection in a triple quadrupole mass spectrometer. Each isomer is gated in CV space before being trapped in the linear ion trap of the modified mass spectrometer, where they are irradiated by the tuneable output of an optical parametric oscillator and undergo photodissociation to form charged fragments withm/z119, 109, and 94. The photon-normalised intensity of each fragmentation channel is measured and the action spectra for each DMS-gated tautomer are obtained. Our analysis of the action spectra, aided by calculated vibronic spectra and thermochemical data, allow us to assign the two signals in our measured ionograms to specific tautomers of protonated adenine.
UR - http://www.scopus.com/inward/record.url?scp=85115119322&partnerID=8YFLogxK
U2 - 10.1039/d1cp02688g
DO - 10.1039/d1cp02688g
M3 - Article
AN - SCOPUS:85115119322
VL - 23
SP - 19892
EP - 19900
JO - Physical Chemistry Chemical Physics
JF - Physical Chemistry Chemical Physics
SN - 1463-9076
IS - 35
ER -