Details
| Original language | English |
|---|---|
| Pages (from-to) | 387-398 |
| Number of pages | 12 |
| Journal | Journal of Adhesion Science and Technology |
| Volume | 28 |
| Issue number | 3-4 |
| Publication status | Published - 10 Aug 2012 |
| Externally published | Yes |
Abstract
Tissue barbs are small-scale structures that may be used for sutureless joining of tissues. In this study, several types of tissue barbs were fabricated using two-photon polymerization/micromolding, including two-pronged tissue barbs, eight-pronged tissue barbs, 10-pronged tissue barbs, and 16-pronged tissue barbs. Tissue barb penetration in porcine tissue was observed using confocal laser scanning microscopy. Constructs containing medical tape and tissue barbs were created by applying tissue barbs in a parallel arrangement to Transpore™ medical tape. These results suggest that two-photon polymerization/micromolding is an indirect rapid prototyping approach that may be used for high-throughput replication of tissue barbs and other microstructured solid wound sealants.
Keywords
- Indirect rapid prototyping, Micromolding, Tissue barb, Two-photon polymerization, Wound sealant
ASJC Scopus subject areas
- Chemistry(all)
- General Chemistry
- Engineering(all)
- Mechanics of Materials
- Physics and Astronomy(all)
- Surfaces and Interfaces
- Materials Science(all)
- Surfaces, Coatings and Films
- Materials Science(all)
- Materials Chemistry
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In: Journal of Adhesion Science and Technology, Vol. 28, No. 3-4, 10.08.2012, p. 387-398.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Two-photon polymerization/micromolding of microscale barbs for medical applications
AU - Boehm, R. D.
AU - Chen, B.
AU - Gittard, S. D.
AU - Chichkov, B. N.
AU - Monteiro-Riviere, N. A.
AU - Nasir, A.
AU - Narayan, R. J.
PY - 2012/8/10
Y1 - 2012/8/10
N2 - Tissue barbs are small-scale structures that may be used for sutureless joining of tissues. In this study, several types of tissue barbs were fabricated using two-photon polymerization/micromolding, including two-pronged tissue barbs, eight-pronged tissue barbs, 10-pronged tissue barbs, and 16-pronged tissue barbs. Tissue barb penetration in porcine tissue was observed using confocal laser scanning microscopy. Constructs containing medical tape and tissue barbs were created by applying tissue barbs in a parallel arrangement to Transpore™ medical tape. These results suggest that two-photon polymerization/micromolding is an indirect rapid prototyping approach that may be used for high-throughput replication of tissue barbs and other microstructured solid wound sealants.
AB - Tissue barbs are small-scale structures that may be used for sutureless joining of tissues. In this study, several types of tissue barbs were fabricated using two-photon polymerization/micromolding, including two-pronged tissue barbs, eight-pronged tissue barbs, 10-pronged tissue barbs, and 16-pronged tissue barbs. Tissue barb penetration in porcine tissue was observed using confocal laser scanning microscopy. Constructs containing medical tape and tissue barbs were created by applying tissue barbs in a parallel arrangement to Transpore™ medical tape. These results suggest that two-photon polymerization/micromolding is an indirect rapid prototyping approach that may be used for high-throughput replication of tissue barbs and other microstructured solid wound sealants.
KW - Indirect rapid prototyping
KW - Micromolding
KW - Tissue barb
KW - Two-photon polymerization
KW - Wound sealant
UR - http://www.scopus.com/inward/record.url?scp=84889637953&partnerID=8YFLogxK
U2 - 10.1080/01694243.2012.693828
DO - 10.1080/01694243.2012.693828
M3 - Article
AN - SCOPUS:84889637953
VL - 28
SP - 387
EP - 398
JO - Journal of Adhesion Science and Technology
JF - Journal of Adhesion Science and Technology
SN - 0169-4243
IS - 3-4
ER -