Details
| Original language | English |
|---|---|
| Pages (from-to) | 2381-2394 |
| Number of pages | 14 |
| Journal | SYNTHESIS-STUTTGART |
| Volume | 53 |
| Issue number | 14 |
| Early online date | 26 Feb 2021 |
| Publication status | Published - 20 Jul 2021 |
Abstract
Total biosynthesis in fungi is beginning to compete with traditional chemical total synthesis campaigns. Herein, the advantages, disadvantages and future opportunities are discussed within the scope of several recent examples. 1 Introduction 2 Synthetic Examples 2.1 2-Pyridones 2.2 Cytochalasans 2.3 Sorbicillinoids 2.4 Decalins: Solanapyrone 2.5 α-Pyrone Polyenes: Citreoviridin and Aurovertin 2.6 Anditomin and Related Meroterpenoids 2.7 Tropolone Sesquiterpenoids 3 Conclusion.
Keywords
- pyridone, cytochalasan, sorbicillinoid, decalin, alpha-pyrone, meroterpenoid, tropolone sesquiterpenoid, α-pyrone
ASJC Scopus subject areas
- Chemical Engineering(all)
- Catalysis
- Chemistry(all)
- Organic Chemistry
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In: SYNTHESIS-STUTTGART, Vol. 53, No. 14, 20.07.2021, p. 2381-2394.
Research output: Contribution to journal › Article › Research
}
TY - JOUR
T1 - Total Mycosynthesis: Rational Bioconstruction and Bioengineering of Fungal Natural Products
AU - Kahlert, Lukas
AU - Schotte, Carsten
AU - Cox, Russell J.
N1 - Funding Information: R.J.C. acknowledges support from DFG in Germany and EPSRC and BBSRC in the UK for project funding. Long-term support has been provided by the universities of Hannover and Bristol, and collaborations with Glaxo, Syngenta and Bayer are gratefully acknowledged. L.K. is funded by DFG (CO 1328/5-1) and C.S. by Leibniz Universität Hannover.DeuscheFoschungsgemeinchaftCO1328/51)
PY - 2021/7/20
Y1 - 2021/7/20
N2 - Total biosynthesis in fungi is beginning to compete with traditional chemical total synthesis campaigns. Herein, the advantages, disadvantages and future opportunities are discussed within the scope of several recent examples. 1 Introduction 2 Synthetic Examples 2.1 2-Pyridones 2.2 Cytochalasans 2.3 Sorbicillinoids 2.4 Decalins: Solanapyrone 2.5 α-Pyrone Polyenes: Citreoviridin and Aurovertin 2.6 Anditomin and Related Meroterpenoids 2.7 Tropolone Sesquiterpenoids 3 Conclusion.
AB - Total biosynthesis in fungi is beginning to compete with traditional chemical total synthesis campaigns. Herein, the advantages, disadvantages and future opportunities are discussed within the scope of several recent examples. 1 Introduction 2 Synthetic Examples 2.1 2-Pyridones 2.2 Cytochalasans 2.3 Sorbicillinoids 2.4 Decalins: Solanapyrone 2.5 α-Pyrone Polyenes: Citreoviridin and Aurovertin 2.6 Anditomin and Related Meroterpenoids 2.7 Tropolone Sesquiterpenoids 3 Conclusion.
KW - pyridone
KW - cytochalasan
KW - sorbicillinoid
KW - decalin
KW - alpha-pyrone
KW - meroterpenoid
KW - tropolone sesquiterpenoid
KW - α-pyrone
UR - http://www.scopus.com/inward/record.url?scp=85102888815&partnerID=8YFLogxK
U2 - 10.1055/a-1401-2716
DO - 10.1055/a-1401-2716
M3 - Article
VL - 53
SP - 2381
EP - 2394
JO - SYNTHESIS-STUTTGART
JF - SYNTHESIS-STUTTGART
SN - 0039-7881
IS - 14
ER -