Details
| Original language | English |
|---|---|
| Article number | e37819 |
| Number of pages | 15 |
| Journal | Journal of Biomedical Materials Research - Part A |
| Volume | 113 |
| Issue number | 1 |
| Publication status | Published - 25 Dec 2024 |
Abstract
There is an urgent need to enhance the mechanical and biotribological performance of polymeric materials utilized in biomedical devices such as load-bearing artificial joints, notably ultrahigh molecular weight polyethylene (UHMWPE). While two-dimensional (2D) materials like graphene, graphene oxide (GO), reduced GO, or hexagonal boron nitride (h-BN) have shown promise as reinforcement phases in polymer matrix composites (PMCs), the potential of MXenes, known for their chemical inertness, mechanical robustness, and wear-resistance, remains largely unexplored in biotribology. This study aims to address this gap by fabricating Ti3C2Tx-UHMWPE nanocomposites using compression molding. Primary objectives include enhancements in mechanical properties, biocompatibility, and biotribological performance, particularly in terms of friction and wear resistance in cobalt chromium alloy pin-on-UHMWPE disk experiments lubricated by artificial synovial fluid. Thereby, no substantial changes in the indentation hardness or the elastic modulus are observed, while the analysis of the resulting wettability and surface tension as well as indirect and direct in vitro evaluation do not point towards cytotoxicity. Most importantly, Ti3C2Tx-reinforced PMCs substantially reduce friction and wear by up to 19% and 44%, respectively, which was attributed to the formation of an easy-to-shear transfer film.
Keywords
- 2D materials, biotribology, MXenes, polymer matrix composites, UHMWPE
ASJC Scopus subject areas
- Materials Science(all)
- Ceramics and Composites
- Materials Science(all)
- Biomaterials
- Engineering(all)
- Biomedical Engineering
- Materials Science(all)
- Metals and Alloys
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In: Journal of Biomedical Materials Research - Part A, Vol. 113, No. 1, e37819, 25.12.2024.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Ti3C2Tx-UHMWPE Nanocomposites
T2 - Towards an Enhanced Wear-Resistance of Biomedical Implants
AU - Rothammer, Benedict
AU - Feile, Klara
AU - Werner, Siegfried
AU - Frank, Rainer
AU - Bartz, Marcel
AU - Wartzack, Sandro
AU - Schubert, Dirk W.
AU - Drummer, Dietmar
AU - Detsch, Rainer
AU - Wang, Bo
AU - Rosenkranz, Andreas
AU - Marian, Max
N1 - Publisher Copyright: © 2024 The Author(s). Journal of Biomedical Materials Research Part A published by Wiley Periodicals LLC.
PY - 2024/12/25
Y1 - 2024/12/25
N2 - There is an urgent need to enhance the mechanical and biotribological performance of polymeric materials utilized in biomedical devices such as load-bearing artificial joints, notably ultrahigh molecular weight polyethylene (UHMWPE). While two-dimensional (2D) materials like graphene, graphene oxide (GO), reduced GO, or hexagonal boron nitride (h-BN) have shown promise as reinforcement phases in polymer matrix composites (PMCs), the potential of MXenes, known for their chemical inertness, mechanical robustness, and wear-resistance, remains largely unexplored in biotribology. This study aims to address this gap by fabricating Ti3C2Tx-UHMWPE nanocomposites using compression molding. Primary objectives include enhancements in mechanical properties, biocompatibility, and biotribological performance, particularly in terms of friction and wear resistance in cobalt chromium alloy pin-on-UHMWPE disk experiments lubricated by artificial synovial fluid. Thereby, no substantial changes in the indentation hardness or the elastic modulus are observed, while the analysis of the resulting wettability and surface tension as well as indirect and direct in vitro evaluation do not point towards cytotoxicity. Most importantly, Ti3C2Tx-reinforced PMCs substantially reduce friction and wear by up to 19% and 44%, respectively, which was attributed to the formation of an easy-to-shear transfer film.
AB - There is an urgent need to enhance the mechanical and biotribological performance of polymeric materials utilized in biomedical devices such as load-bearing artificial joints, notably ultrahigh molecular weight polyethylene (UHMWPE). While two-dimensional (2D) materials like graphene, graphene oxide (GO), reduced GO, or hexagonal boron nitride (h-BN) have shown promise as reinforcement phases in polymer matrix composites (PMCs), the potential of MXenes, known for their chemical inertness, mechanical robustness, and wear-resistance, remains largely unexplored in biotribology. This study aims to address this gap by fabricating Ti3C2Tx-UHMWPE nanocomposites using compression molding. Primary objectives include enhancements in mechanical properties, biocompatibility, and biotribological performance, particularly in terms of friction and wear resistance in cobalt chromium alloy pin-on-UHMWPE disk experiments lubricated by artificial synovial fluid. Thereby, no substantial changes in the indentation hardness or the elastic modulus are observed, while the analysis of the resulting wettability and surface tension as well as indirect and direct in vitro evaluation do not point towards cytotoxicity. Most importantly, Ti3C2Tx-reinforced PMCs substantially reduce friction and wear by up to 19% and 44%, respectively, which was attributed to the formation of an easy-to-shear transfer film.
KW - 2D materials
KW - biotribology
KW - MXenes
KW - polymer matrix composites
KW - UHMWPE
UR - http://www.scopus.com/inward/record.url?scp=85207499291&partnerID=8YFLogxK
U2 - 10.1002/jbm.a.37819
DO - 10.1002/jbm.a.37819
M3 - Article
C2 - 39446576
AN - SCOPUS:85207499291
VL - 113
JO - Journal of Biomedical Materials Research - Part A
JF - Journal of Biomedical Materials Research - Part A
SN - 1549-3296
IS - 1
M1 - e37819
ER -