Details
Original language | English |
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Pages (from-to) | 7201-7204 |
Number of pages | 4 |
Journal | Tetrahedron letters |
Volume | 40 |
Issue number | 40 |
Publication status | Published - 1 Oct 1999 |
Abstract
Ratjadone is an antifungal and highly cytotoxic polyketide from Sorangium cellulosum. The tetrahydropyran ring is supposed to result from an intramolecular opening of a C16-C17 epoxide. Herein we report the biomimetic synthesis of the C15-C24 segment of ratjadone.
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Biochemistry
- Pharmacology, Toxicology and Pharmaceutics(all)
- Drug Discovery
- Chemistry(all)
- Organic Chemistry
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In: Tetrahedron letters, Vol. 40, No. 40, 01.10.1999, p. 7201-7204.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - The synthesis of the C15-C24 segment of ratjadone
AU - Christmann, Mathias
AU - Kalesse, Markus
PY - 1999/10/1
Y1 - 1999/10/1
N2 - Ratjadone is an antifungal and highly cytotoxic polyketide from Sorangium cellulosum. The tetrahydropyran ring is supposed to result from an intramolecular opening of a C16-C17 epoxide. Herein we report the biomimetic synthesis of the C15-C24 segment of ratjadone.
AB - Ratjadone is an antifungal and highly cytotoxic polyketide from Sorangium cellulosum. The tetrahydropyran ring is supposed to result from an intramolecular opening of a C16-C17 epoxide. Herein we report the biomimetic synthesis of the C15-C24 segment of ratjadone.
UR - http://www.scopus.com/inward/record.url?scp=0033214272&partnerID=8YFLogxK
U2 - 10.1016/S0040-4039(99)01486-0
DO - 10.1016/S0040-4039(99)01486-0
M3 - Article
AN - SCOPUS:0033214272
VL - 40
SP - 7201
EP - 7204
JO - Tetrahedron letters
JF - Tetrahedron letters
SN - 0040-4039
IS - 40
ER -