Details
| Original language | English |
|---|---|
| Pages (from-to) | 173-774 |
| Number of pages | 602 |
| Journal | Organic Reactions |
| Volume | 98 |
| Publication status | Published - 11 Mar 2019 |
Abstract
ASJC Scopus subject areas
- Chemistry(all)
- Physical and Theoretical Chemistry
- Chemistry(all)
- Organic Chemistry
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In: Organic Reactions, Vol. 98, 11.03.2019, p. 173-774.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - The asymmetric vinylogous mukaiyama aldol reaction
AU - Cordes, Martin H. C.
AU - Kalesse, Markus
PY - 2019/3/11
Y1 - 2019/3/11
N2 - The vinylogous Mukaiyama aldol (VMA) reaction allows efficient access to larger segments for complex natural product synthesis, primarily polyketides, through the construction of vicinal hydroxyl and methyl groups as well as di- and tri-substituted double bonds in a single operation. In this chapter, the current scope and limitations of this transformation, as well as its application in natural product synthesis, are discussed.
AB - The vinylogous Mukaiyama aldol (VMA) reaction allows efficient access to larger segments for complex natural product synthesis, primarily polyketides, through the construction of vicinal hydroxyl and methyl groups as well as di- and tri-substituted double bonds in a single operation. In this chapter, the current scope and limitations of this transformation, as well as its application in natural product synthesis, are discussed.
UR - http://www.scopus.com/inward/record.url?scp=85067595948&partnerID=8YFLogxK
U2 - 10.1002/0471264180.or098.02
DO - 10.1002/0471264180.or098.02
M3 - Article
AN - SCOPUS:85067595948
VL - 98
SP - 173
EP - 774
JO - Organic Reactions
JF - Organic Reactions
SN - 0078-6179
ER -