Tests auf das Humanpapillomavirus (HPV) in der Zervixkarzinomfrü herkennung

Research output: Contribution to journal › Article › Research › peer review

Authors

  • Marc Nocon
  • Stephanie Roll
  • Thomas Mittendorf
  • J. Matthias Von der Schulenburg
  • Stefan N. Willich

Research Organisations

External Research Organisations

  • Charité - Universitätsmedizin Berlin
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Details

Translated title of the contributionHuman papilloma virus (HPV) testing for cervical carcinoma screening
Original languageMultiple languages
Pages (from-to)138-142
Number of pages5
JournalZeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen
Volume104
Issue number2
Early online date30 Jul 2008
Publication statusPublished - 2010

Abstract

Cytology-based screening for cervical cancer has been criticised because of its high percentage of false-negative results. Considering HPV testing as an integral part of the screening process has been discussed as a way to address this issue in Germany. The aim of our study was to review trials comparing HPV testing with cytology in cervical cancer screening. Based on a systematic literature review, 14 studies with 85, 820 women could be included. Generally HPV testing was more sensitive, but less specific than cytology. Based on the pooled data, sensitivity and specificity for HPV testing were 91 % and 90%, respectively, whereas sensitivity and specificity for cytology amounted to 66% and 96%, respectively. Based on these results, including HPV testing in primary cervical cancer screening might lead to a reduction of false-negative results. Due the lower specificity false-positive test results would increase though.

ASJC Scopus subject areas

Sustainable Development Goals

Cite this

Tests auf das Humanpapillomavirus (HPV) in der Zervixkarzinomfrü herkennung. / Nocon, Marc; Roll, Stephanie; Mittendorf, Thomas et al.
In: Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen, Vol. 104, No. 2, 2010, p. 138-142.

Research output: Contribution to journal › Article › Research › peer review

Nocon, M, Roll, S, Mittendorf, T, Von der Schulenburg, JM & Willich, SN 2010, 'Tests auf das Humanpapillomavirus (HPV) in der Zervixkarzinomfrü herkennung', Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen, vol. 104, no. 2, pp. 138-142. https://doi.org/10.1016/j.zefq.2008.06.018
Nocon, M., Roll, S., Mittendorf, T., Von der Schulenburg, J. M., & Willich, S. N. (2010). Tests auf das Humanpapillomavirus (HPV) in der Zervixkarzinomfrü herkennung. Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen, 104(2), 138-142. https://doi.org/10.1016/j.zefq.2008.06.018
Nocon M, Roll S, Mittendorf T, Von der Schulenburg JM, Willich SN. Tests auf das Humanpapillomavirus (HPV) in der Zervixkarzinomfrü herkennung. Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen. 2010;104(2):138-142. Epub 2008 Jul 30. doi: 10.1016/j.zefq.2008.06.018
Nocon, Marc ; Roll, Stephanie ; Mittendorf, Thomas et al. / Tests auf das Humanpapillomavirus (HPV) in der Zervixkarzinomfrü herkennung. In: Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen. 2010 ; Vol. 104, No. 2. pp. 138-142.
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AU - Roll, Stephanie

AU - Mittendorf, Thomas

AU - Von der Schulenburg, J. Matthias

AU - Willich, Stefan N.

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