Details
| Original language | English |
|---|---|
| Pages (from-to) | 158-161 |
| Number of pages | 4 |
| Journal | Current Directions in Biomedical Engineering |
| Volume | 9 |
| Issue number | 1 |
| Publication status | Published - 1 Sept 2023 |
Abstract
The Diels-Alder (DA) reaction is one of the most studied thermoreversible reactions, suitable for the preparation of thermoreversible crosslinked materials. In this study, temperature- triggered liquefaction of DA hydrogels will be investigated. A DA model reaction is used to determine the retro- DA temperature of the two stereoisomers. A hydrogel based on furan-functionalized Poly-(N-(2-hydroxy-propyl) methacryl amide (PHPMA) and 4-arm-polyethylene glycol (PEG) with maleimide endgroups is rheologically investigated and liquefaction experiments are performed.
Keywords
- Diels-Alder, thermoreversible hydrogel
ASJC Scopus subject areas
- Engineering(all)
- Biomedical Engineering
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In: Current Directions in Biomedical Engineering, Vol. 9, No. 1, 01.09.2023, p. 158-161.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Temperature-triggered liquefication of hydrogels for intentional implant removal
AU - Finck, Laura
AU - Hagemann, Valentin
AU - Behrens, Peter
AU - Menzel, Henning
PY - 2023/9/1
Y1 - 2023/9/1
N2 - The Diels-Alder (DA) reaction is one of the most studied thermoreversible reactions, suitable for the preparation of thermoreversible crosslinked materials. In this study, temperature- triggered liquefaction of DA hydrogels will be investigated. A DA model reaction is used to determine the retro- DA temperature of the two stereoisomers. A hydrogel based on furan-functionalized Poly-(N-(2-hydroxy-propyl) methacryl amide (PHPMA) and 4-arm-polyethylene glycol (PEG) with maleimide endgroups is rheologically investigated and liquefaction experiments are performed.
AB - The Diels-Alder (DA) reaction is one of the most studied thermoreversible reactions, suitable for the preparation of thermoreversible crosslinked materials. In this study, temperature- triggered liquefaction of DA hydrogels will be investigated. A DA model reaction is used to determine the retro- DA temperature of the two stereoisomers. A hydrogel based on furan-functionalized Poly-(N-(2-hydroxy-propyl) methacryl amide (PHPMA) and 4-arm-polyethylene glycol (PEG) with maleimide endgroups is rheologically investigated and liquefaction experiments are performed.
KW - Diels-Alder
KW - thermoreversible hydrogel
UR - http://www.scopus.com/inward/record.url?scp=85173579049&partnerID=8YFLogxK
U2 - 10.1515/cdbme-2023-1040
DO - 10.1515/cdbme-2023-1040
M3 - Article
AN - SCOPUS:85173579049
VL - 9
SP - 158
EP - 161
JO - Current Directions in Biomedical Engineering
JF - Current Directions in Biomedical Engineering
IS - 1
ER -