Details
| Original language | English |
|---|---|
| Pages (from-to) | 7931-7939 |
| Number of pages | 9 |
| Journal | Ceramics international |
| Volume | 40 |
| Issue number | 6 |
| Publication status | Published - 7 Jan 2014 |
| Externally published | Yes |
Abstract
Calcium phosphates, functionalized with nano-sized metal particles, are a promising material class for the treatment of bone defects. However, a sintering process is required in principle to achieve sufficient strength of calcium phosphate scaffolds. In this work laser-generated nano-sized silver, gold and platinum particles were adsorbed on micro-sized β-tricalcium phosphate particles and further heat treated at temperatures between 600 and 1200 °C. Gold and platinum nanoparticles underwent exponential growth starting at about 600 °C, while sintering of β-tricalcium phosphate started at 800 °C. We hypothesise that this phenomenon is caused by a heat-induced evaporation and growth process where the decrease of the particle number is directly correlated with the size increase. The silver nanoparticles on the other hand formed a new phase with the calcium phosphate (AgCa 10(PO4)7) during the heat treatments and could not be observed within the ceramic scaffold anymore. Addressing the lack of information in nanoparticle-combined calcium phosphate scaffolds, this study contributes to the further modification of bone replacement materials with biologically relevant functions and molecules.
Keywords
- A. Sintering, B. Nanocomposites, E. Biomedical application, Pulsed laser ablation
ASJC Scopus subject areas
- Materials Science(all)
- Electronic, Optical and Magnetic Materials
- Materials Science(all)
- Ceramics and Composites
- Chemical Engineering(all)
- Process Chemistry and Technology
- Materials Science(all)
- Surfaces, Coatings and Films
- Materials Science(all)
- Materials Chemistry
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In: Ceramics international, Vol. 40, No. 6, 07.01.2014, p. 7931-7939.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Temperature-dependent morphology changes of noble metal tricalcium phosphate-nanocomposites
AU - Bergmann, Christian
AU - Schwenke, Andreas
AU - Sajti, Laszlo
AU - Chichkov, Boris
AU - Fischer, Horst
N1 - Funding information: This work was supported by the German Research Foundation (DFG) within the cluster of excellence “REBIRTH” (From Regenerative Biology to Reconstructive Therapy).
PY - 2014/1/7
Y1 - 2014/1/7
N2 - Calcium phosphates, functionalized with nano-sized metal particles, are a promising material class for the treatment of bone defects. However, a sintering process is required in principle to achieve sufficient strength of calcium phosphate scaffolds. In this work laser-generated nano-sized silver, gold and platinum particles were adsorbed on micro-sized β-tricalcium phosphate particles and further heat treated at temperatures between 600 and 1200 °C. Gold and platinum nanoparticles underwent exponential growth starting at about 600 °C, while sintering of β-tricalcium phosphate started at 800 °C. We hypothesise that this phenomenon is caused by a heat-induced evaporation and growth process where the decrease of the particle number is directly correlated with the size increase. The silver nanoparticles on the other hand formed a new phase with the calcium phosphate (AgCa 10(PO4)7) during the heat treatments and could not be observed within the ceramic scaffold anymore. Addressing the lack of information in nanoparticle-combined calcium phosphate scaffolds, this study contributes to the further modification of bone replacement materials with biologically relevant functions and molecules.
AB - Calcium phosphates, functionalized with nano-sized metal particles, are a promising material class for the treatment of bone defects. However, a sintering process is required in principle to achieve sufficient strength of calcium phosphate scaffolds. In this work laser-generated nano-sized silver, gold and platinum particles were adsorbed on micro-sized β-tricalcium phosphate particles and further heat treated at temperatures between 600 and 1200 °C. Gold and platinum nanoparticles underwent exponential growth starting at about 600 °C, while sintering of β-tricalcium phosphate started at 800 °C. We hypothesise that this phenomenon is caused by a heat-induced evaporation and growth process where the decrease of the particle number is directly correlated with the size increase. The silver nanoparticles on the other hand formed a new phase with the calcium phosphate (AgCa 10(PO4)7) during the heat treatments and could not be observed within the ceramic scaffold anymore. Addressing the lack of information in nanoparticle-combined calcium phosphate scaffolds, this study contributes to the further modification of bone replacement materials with biologically relevant functions and molecules.
KW - A. Sintering
KW - B. Nanocomposites
KW - E. Biomedical application
KW - Pulsed laser ablation
UR - http://www.scopus.com/inward/record.url?scp=84897422230&partnerID=8YFLogxK
U2 - 10.1016/j.ceramint.2013.12.141
DO - 10.1016/j.ceramint.2013.12.141
M3 - Article
AN - SCOPUS:84897422230
VL - 40
SP - 7931
EP - 7939
JO - Ceramics international
JF - Ceramics international
SN - 0272-8842
IS - 6
ER -