Details
| Original language | English |
|---|---|
| Pages (from-to) | 817-820 |
| Number of pages | 4 |
| Journal | Tetrahedron Asymmetry |
| Volume | 10 |
| Issue number | 5 |
| Publication status | Published - 12 Mar 1999 |
| Externally published | Yes |
Abstract
Practical syntheses of the C9-C14 sterotriade 5 and the C1-C8 polyene unit 6 in ansatrienine A (mycotriene) (1a), and other ansamycin antibiotics is described. A key step for controlling the configuration of the stereogenic center at C13 involves the stereoselective reduction of enone 10 using the Evans-Tishchenko reaction.
ASJC Scopus subject areas
- Chemical Engineering(all)
- Catalysis
- Chemistry(all)
- Physical and Theoretical Chemistry
- Chemistry(all)
- Organic Chemistry
- Chemistry(all)
- Inorganic Chemistry
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In: Tetrahedron Asymmetry, Vol. 10, No. 5, 12.03.1999, p. 817-820.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Synthetic studies toward ansatrienines
T2 - Application of the Evans- Tishchenko reaction to chiral enones
AU - Schöning, Kai Uwe
AU - Hayashi, R. K.
AU - Powell, Douglas R.
AU - Kirschning, Andreas
N1 - Funding information: We thank the Fonds der Chemischen Industrie and the National Science Foundation (grant CHE-9310428) for financial support. Donation of chemicals from E. Merck AG (Darmstadt) is gratefully acknowledged.
PY - 1999/3/12
Y1 - 1999/3/12
N2 - Practical syntheses of the C9-C14 sterotriade 5 and the C1-C8 polyene unit 6 in ansatrienine A (mycotriene) (1a), and other ansamycin antibiotics is described. A key step for controlling the configuration of the stereogenic center at C13 involves the stereoselective reduction of enone 10 using the Evans-Tishchenko reaction.
AB - Practical syntheses of the C9-C14 sterotriade 5 and the C1-C8 polyene unit 6 in ansatrienine A (mycotriene) (1a), and other ansamycin antibiotics is described. A key step for controlling the configuration of the stereogenic center at C13 involves the stereoselective reduction of enone 10 using the Evans-Tishchenko reaction.
UR - http://www.scopus.com/inward/record.url?scp=0141964973&partnerID=8YFLogxK
U2 - 10.1016/S0957-4166(99)00069-5
DO - 10.1016/S0957-4166(99)00069-5
M3 - Article
AN - SCOPUS:0141964973
VL - 10
SP - 817
EP - 820
JO - Tetrahedron Asymmetry
JF - Tetrahedron Asymmetry
SN - 0957-4166
IS - 5
ER -