Details
| Original language | English |
|---|---|
| Pages (from-to) | 4157-4160 |
| Number of pages | 4 |
| Journal | Tetrahedron letters |
| Volume | 40 |
| Issue number | 22 |
| Publication status | Published - 28 May 1999 |
Abstract
The Pd-catalyzed synthesis of the polyene fragment of ratjadone is described. This strategy employs the Stille-coupling for the coupling of the tetrahydropyran subunit and the Suzuki coupling for attaching the unsaturated lactone to the polyene chain.
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Biochemistry
- Pharmacology, Toxicology and Pharmaceutics(all)
- Drug Discovery
- Chemistry(all)
- Organic Chemistry
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In: Tetrahedron letters, Vol. 40, No. 22, 28.05.1999, p. 4157-4160.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Synthesis of the C6-C16 polyene fragment of ratjadone, a potent cytotoxic metabolite from Sorangium cellulosum
AU - Claus, Eckhard
AU - Kalesse, Markus
PY - 1999/5/28
Y1 - 1999/5/28
N2 - The Pd-catalyzed synthesis of the polyene fragment of ratjadone is described. This strategy employs the Stille-coupling for the coupling of the tetrahydropyran subunit and the Suzuki coupling for attaching the unsaturated lactone to the polyene chain.
AB - The Pd-catalyzed synthesis of the polyene fragment of ratjadone is described. This strategy employs the Stille-coupling for the coupling of the tetrahydropyran subunit and the Suzuki coupling for attaching the unsaturated lactone to the polyene chain.
UR - http://www.scopus.com/inward/record.url?scp=0033612262&partnerID=8YFLogxK
U2 - 10.1016/S0040-4039(99)00716-9
DO - 10.1016/S0040-4039(99)00716-9
M3 - Article
AN - SCOPUS:0033612262
VL - 40
SP - 4157
EP - 4160
JO - Tetrahedron letters
JF - Tetrahedron letters
SN - 0040-4039
IS - 22
ER -