Details
| Original language | English |
|---|---|
| Pages (from-to) | 1359-1362 |
| Number of pages | 4 |
| Journal | Tetrahedron letters |
| Volume | 38 |
| Issue number | 8 |
| Publication status | Published - 24 Feb 1997 |
| Externally published | Yes |
Abstract
The C1-C9 segment of epothilons was generated by an aldol reaction between chiral aldehyde 3 and ethyl ketone 4. Removal of the TBS protecting groups and debenzylation generated spiro ketal 13 which was analyzed by X-ray crystallography.
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Biochemistry
- Pharmacology, Toxicology and Pharmaceutics(all)
- Drug Discovery
- Chemistry(all)
- Organic Chemistry
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In: Tetrahedron letters, Vol. 38, No. 8, 24.02.1997, p. 1359-1362.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Synthesis of the C1-C9 segment of epothilons
AU - Claus, Eckhard
AU - Pahl, Axel
AU - Jones, Peter G.
AU - Meyer, Hartmut M.
AU - Kalesse, Markus
PY - 1997/2/24
Y1 - 1997/2/24
N2 - The C1-C9 segment of epothilons was generated by an aldol reaction between chiral aldehyde 3 and ethyl ketone 4. Removal of the TBS protecting groups and debenzylation generated spiro ketal 13 which was analyzed by X-ray crystallography.
AB - The C1-C9 segment of epothilons was generated by an aldol reaction between chiral aldehyde 3 and ethyl ketone 4. Removal of the TBS protecting groups and debenzylation generated spiro ketal 13 which was analyzed by X-ray crystallography.
UR - http://www.scopus.com/inward/record.url?scp=0031584881&partnerID=8YFLogxK
U2 - 10.1016/S0040-4039(96)02493-8
DO - 10.1016/S0040-4039(96)02493-8
M3 - Article
AN - SCOPUS:0031584881
VL - 38
SP - 1359
EP - 1362
JO - Tetrahedron letters
JF - Tetrahedron letters
SN - 0040-4039
IS - 8
ER -