Details
| Original language | English |
|---|---|
| Pages (from-to) | 419-422 |
| Number of pages | 4 |
| Journal | Synlett |
| Issue number | 3 |
| Publication status | Published - 6 Feb 2006 |
Abstract
The enantioselective synthesis of the C1-C5 and C6-C24 fragments of the ripostatins utilize a Negishi coupling, two Nagao acetate aldol reactions followed by a Denmark vinylogous aldol reaction and Stille couplings as key C-C bond forming steps.
Keywords
- Antibiotics, Nagao aldol reaction, Natural product synthesis, RNA polymerase inhibitors, Vinylogous aldol reaction
ASJC Scopus subject areas
- Chemistry(all)
- Organic Chemistry
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In: Synlett, No. 3, 06.02.2006, p. 419-422.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Synthesis of the C1-C5 and C6-C24 fragments of the RNA polymerase inhibitors ripostatin A and B
AU - Kujat, Christof
AU - Bock, Martin
AU - Kirschning, Andreas
PY - 2006/2/6
Y1 - 2006/2/6
N2 - The enantioselective synthesis of the C1-C5 and C6-C24 fragments of the ripostatins utilize a Negishi coupling, two Nagao acetate aldol reactions followed by a Denmark vinylogous aldol reaction and Stille couplings as key C-C bond forming steps.
AB - The enantioselective synthesis of the C1-C5 and C6-C24 fragments of the ripostatins utilize a Negishi coupling, two Nagao acetate aldol reactions followed by a Denmark vinylogous aldol reaction and Stille couplings as key C-C bond forming steps.
KW - Antibiotics
KW - Nagao aldol reaction
KW - Natural product synthesis
KW - RNA polymerase inhibitors
KW - Vinylogous aldol reaction
UR - http://www.scopus.com/inward/record.url?scp=33344459154&partnerID=8YFLogxK
U2 - 10.1055/s-2006-926263
DO - 10.1055/s-2006-926263
M3 - Article
AN - SCOPUS:33344459154
SP - 419
EP - 422
JO - Synlett
JF - Synlett
SN - 0936-5214
IS - 3
ER -