Synthesis of isotopically labelled 3-amino-2-phenylpropionic acid and its role as a precursor in the biosynthesis of tenellin and tropic acid

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Original languageEnglish
Pages (from-to)2537-2540
Number of pages4
JournalJournal of the Chemical Society, Perkin Transactions 1
Issue number10
Publication statusPublished - 1 Dec 1991
Externally publishedYes

Abstract

A synthesis of [3-13C]- and [3-14C]-3-amino-2- phenylpropionic acids 7a and 7b is described. The incorporation of this amino acid into tenellin 1 from Beauveria bassiana (Bals.) Vuill. and into tropic acid 10 moiety of the tropane alkaloids hyscoyamine 8 and scopolamine 9 from Datura innoxia was studied but proved unsuccessful in each case.

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Synthesis of isotopically labelled 3-amino-2-phenylpropionic acid and its role as a precursor in the biosynthesis of tenellin and tropic acid. / Cox, Russell J.; O'Hagan, David.
In: Journal of the Chemical Society, Perkin Transactions 1, No. 10, 01.12.1991, p. 2537-2540.

Research output: Contribution to journalArticleResearchpeer review

Cox RJ, O'Hagan D. Synthesis of isotopically labelled 3-amino-2-phenylpropionic acid and its role as a precursor in the biosynthesis of tenellin and tropic acid. Journal of the Chemical Society, Perkin Transactions 1. 1991 Dec 1;(10):2537-2540. doi: 10.1039/p19910002537
Cox, Russell J. ; O'Hagan, David. / Synthesis of isotopically labelled 3-amino-2-phenylpropionic acid and its role as a precursor in the biosynthesis of tenellin and tropic acid. In: Journal of the Chemical Society, Perkin Transactions 1. 1991 ; No. 10. pp. 2537-2540.
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