Details
| Original language | English |
|---|---|
| Pages (from-to) | 419-445 |
| Number of pages | 27 |
| Journal | Current Topics in Microbiology and Immunology |
| Volume | 398 |
| Publication status | Published - 5 Oct 2016 |
Abstract
The synthesis of b-lactams, tetracyclines, and erythromycins as three of the major families of antibiotics will be described herein. We will describe why these antibiotics were the ultimate synthetic targets in the past and how modern synthetic organic chemistry has evolved to address these challenges with new, improved strategies and methods. An additional aspect we would like to highlight here is the fact that these first syntheses had to be particularly creative as most of the modern synthetic methods were not available at that time, or were developed in the course of these syntheses.
ASJC Scopus subject areas
- Medicine(all)
- Immunology and Allergy
- Immunology and Microbiology(all)
- Microbiology
- Immunology and Microbiology(all)
- Immunology
- Medicine(all)
- Microbiology (medical)
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In: Current Topics in Microbiology and Immunology, Vol. 398, 05.10.2016, p. 419-445.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Synthesis of antibiotics
AU - Kalesse, Markus
AU - Böhm, Andreas
AU - Kipper, Andi
AU - Wandelt, Vanessa
PY - 2016/10/5
Y1 - 2016/10/5
N2 - The synthesis of b-lactams, tetracyclines, and erythromycins as three of the major families of antibiotics will be described herein. We will describe why these antibiotics were the ultimate synthetic targets in the past and how modern synthetic organic chemistry has evolved to address these challenges with new, improved strategies and methods. An additional aspect we would like to highlight here is the fact that these first syntheses had to be particularly creative as most of the modern synthetic methods were not available at that time, or were developed in the course of these syntheses.
AB - The synthesis of b-lactams, tetracyclines, and erythromycins as three of the major families of antibiotics will be described herein. We will describe why these antibiotics were the ultimate synthetic targets in the past and how modern synthetic organic chemistry has evolved to address these challenges with new, improved strategies and methods. An additional aspect we would like to highlight here is the fact that these first syntheses had to be particularly creative as most of the modern synthetic methods were not available at that time, or were developed in the course of these syntheses.
UR - http://www.scopus.com/inward/record.url?scp=85007321220&partnerID=8YFLogxK
U2 - 10.1007/82_2016_502
DO - 10.1007/82_2016_502
M3 - Article
C2 - 27704271
AN - SCOPUS:85007321220
VL - 398
SP - 419
EP - 445
JO - Current Topics in Microbiology and Immunology
JF - Current Topics in Microbiology and Immunology
SN - 0070-217X
ER -