Details
| Original language | English |
|---|---|
| Pages (from-to) | 46-50 |
| Number of pages | 5 |
| Journal | CHEMBIOCHEM |
| Volume | 8 |
| Issue number | 1 |
| Publication status | Published - 2007 |
| Externally published | Yes |
Abstract
Fungal PKS/NRPS: [1,2-13C2,15N]-L- Homoserine has been prepared from [13C2, 15N]-glycine in good yield. Incubation studies with cultures of the fungus Fusarium moniliforme confirm its intact incorporation into the pyrrolidinone ring of fusarin C.
Keywords
- Amino acids, Biosynthesis, Fusarin C, Isotopic labeling, PKS/NRPS
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Biochemistry
- Biochemistry, Genetics and Molecular Biology(all)
- Molecular Medicine
- Biochemistry, Genetics and Molecular Biology(all)
- Molecular Biology
- Chemistry(all)
- Organic Chemistry
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In: CHEMBIOCHEM, Vol. 8, No. 1, 2007, p. 46-50.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Synthesis of [1,2-13C2,15N]-L-homoserine and its incorporation by the PKS-NRPS system of Fusarium moniliforme into the mycotoxin fusarin C
AU - Rees, David O.
AU - Bushby, Nick
AU - Cox, Russell J.
AU - Harding, John R.
AU - Simpson, Thomas J.
AU - Willis, Christine L.
PY - 2007
Y1 - 2007
N2 - Fungal PKS/NRPS: [1,2-13C2,15N]-L- Homoserine has been prepared from [13C2, 15N]-glycine in good yield. Incubation studies with cultures of the fungus Fusarium moniliforme confirm its intact incorporation into the pyrrolidinone ring of fusarin C.
AB - Fungal PKS/NRPS: [1,2-13C2,15N]-L- Homoserine has been prepared from [13C2, 15N]-glycine in good yield. Incubation studies with cultures of the fungus Fusarium moniliforme confirm its intact incorporation into the pyrrolidinone ring of fusarin C.
KW - Amino acids
KW - Biosynthesis
KW - Fusarin C
KW - Isotopic labeling
KW - PKS/NRPS
UR - http://www.scopus.com/inward/record.url?scp=33846283454&partnerID=8YFLogxK
U2 - 10.1002/cbic.200600404
DO - 10.1002/cbic.200600404
M3 - Article
C2 - 17121404
AN - SCOPUS:33846283454
VL - 8
SP - 46
EP - 50
JO - CHEMBIOCHEM
JF - CHEMBIOCHEM
SN - 1439-4227
IS - 1
ER -