Details
| Original language | English |
|---|---|
| Pages (from-to) | 81-96 |
| Number of pages | 16 |
| Journal | Alternatives to laboratory animals |
| Volume | 31 |
| Issue number | SUPPL. 1 |
| Publication status | Published - Nov 2003 |
Abstract
Various tests on trend in toxicological studies are reviewed, and the advantages and the disadvantages involved with such procedures are discussed. New tests are introduced to overcome difficulties common to many current procedures, such as downturns at higher doses, and missing numerical availability.
Keywords
- Contrast test, Dose-response analysis, In vitro toxicological assay, Non-monotone, Trend test
ASJC Scopus subject areas
- Medicine(all)
- General Medicine
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In: Alternatives to laboratory animals, Vol. 31, No. SUPPL. 1, 11.2003, p. 81-96.
Research output: Contribution to journal › Review article › Research › peer review
}
TY - JOUR
T1 - Statistical analysis of monotone or non-monotone dose-response data from in vitro toxicological assays
AU - Bretz, Frank
AU - Hothorn, Ludwig A.
PY - 2003/11
Y1 - 2003/11
N2 - Various tests on trend in toxicological studies are reviewed, and the advantages and the disadvantages involved with such procedures are discussed. New tests are introduced to overcome difficulties common to many current procedures, such as downturns at higher doses, and missing numerical availability.
AB - Various tests on trend in toxicological studies are reviewed, and the advantages and the disadvantages involved with such procedures are discussed. New tests are introduced to overcome difficulties common to many current procedures, such as downturns at higher doses, and missing numerical availability.
KW - Contrast test
KW - Dose-response analysis
KW - In vitro toxicological assay
KW - Non-monotone
KW - Trend test
UR - http://www.scopus.com/inward/record.url?scp=0042697233&partnerID=8YFLogxK
U2 - 10.1177/026119290303101s06
DO - 10.1177/026119290303101s06
M3 - Review article
C2 - 15595903
AN - SCOPUS:0042697233
VL - 31
SP - 81
EP - 96
JO - Alternatives to laboratory animals
JF - Alternatives to laboratory animals
SN - 0261-1929
IS - SUPPL. 1
ER -