Details
| Original language | English |
|---|---|
| Article number | 470295 |
| Pages (from-to) | 6229-6244 |
| Number of pages | 16 |
| Journal | Biomedical optics express |
| Volume | 13 |
| Issue number | 12 |
| Early online date | 7 Nov 2022 |
| Publication status | Published - Dec 2022 |
| Externally published | Yes |
Abstract
One of the main challenges in miniaturizing optoacoustic technology is the low sensitivity of sub-millimeter piezoelectric ultrasound transducers, which is often insufficient for detecting weak optoacoustic signals. Optical detectors of ultrasound can achieve significantly higher sensitivities than their piezoelectric counterparts for a given sensing area but generally lack acoustic focusing, which is essential in many minimally invasive imaging configurations. In this work, we develop a focused sub-millimeter ultrasound detector composed of a silicon-photonics optical resonator and a micro-machined acoustic lens. The acoustic lens provides acoustic focusing, which, in addition to increasing the lateral resolution, also enhances the signal. The developed detector has a wide bandwidth of 84 MHz, a focal width smaller than 50 µm, and noise-equivalent pressure of 37 mPa/Hz1/2 - an order of magnitude improvement over conventional intravascular ultrasound. We show the feasibility of the approach and the detector's imaging capabilities by performing high-resolution optoacoustic microscopy of optical phantoms with complex geometries.
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Biotechnology
- Physics and Astronomy(all)
- Atomic and Molecular Physics, and Optics
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In: Biomedical optics express, Vol. 13, No. 12, 470295, 12.2022, p. 6229-6244.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Silicon-photonics focused ultrasound detector for minimally invasive optoacoustic imaging
AU - Nagli, Michael
AU - Koch, Jürgen
AU - Hazan, Yoav
AU - Volodarsky, Oleg
AU - Kumar, Resmi Ravi
AU - Levi, Ahiad
AU - Hahamovich, Evgeny
AU - Ternyak, Orna
AU - Overmeyer, Ludger
AU - Rosenthal, Amir
N1 - Funding Information: Israel Science Foundation (1709/20 A.R.). We thank the Micro & Nano Fabrication Unit (MNFU) for their help and advice in the device fabrication and for providing clean room facilities.
PY - 2022/12
Y1 - 2022/12
N2 - One of the main challenges in miniaturizing optoacoustic technology is the low sensitivity of sub-millimeter piezoelectric ultrasound transducers, which is often insufficient for detecting weak optoacoustic signals. Optical detectors of ultrasound can achieve significantly higher sensitivities than their piezoelectric counterparts for a given sensing area but generally lack acoustic focusing, which is essential in many minimally invasive imaging configurations. In this work, we develop a focused sub-millimeter ultrasound detector composed of a silicon-photonics optical resonator and a micro-machined acoustic lens. The acoustic lens provides acoustic focusing, which, in addition to increasing the lateral resolution, also enhances the signal. The developed detector has a wide bandwidth of 84 MHz, a focal width smaller than 50 µm, and noise-equivalent pressure of 37 mPa/Hz1/2 - an order of magnitude improvement over conventional intravascular ultrasound. We show the feasibility of the approach and the detector's imaging capabilities by performing high-resolution optoacoustic microscopy of optical phantoms with complex geometries.
AB - One of the main challenges in miniaturizing optoacoustic technology is the low sensitivity of sub-millimeter piezoelectric ultrasound transducers, which is often insufficient for detecting weak optoacoustic signals. Optical detectors of ultrasound can achieve significantly higher sensitivities than their piezoelectric counterparts for a given sensing area but generally lack acoustic focusing, which is essential in many minimally invasive imaging configurations. In this work, we develop a focused sub-millimeter ultrasound detector composed of a silicon-photonics optical resonator and a micro-machined acoustic lens. The acoustic lens provides acoustic focusing, which, in addition to increasing the lateral resolution, also enhances the signal. The developed detector has a wide bandwidth of 84 MHz, a focal width smaller than 50 µm, and noise-equivalent pressure of 37 mPa/Hz1/2 - an order of magnitude improvement over conventional intravascular ultrasound. We show the feasibility of the approach and the detector's imaging capabilities by performing high-resolution optoacoustic microscopy of optical phantoms with complex geometries.
UR - http://www.scopus.com/inward/record.url?scp=85143160530&partnerID=8YFLogxK
U2 - 10.1364/BOE.470295
DO - 10.1364/BOE.470295
M3 - Article
AN - SCOPUS:85143160530
VL - 13
SP - 6229
EP - 6244
JO - Biomedical optics express
JF - Biomedical optics express
SN - 2156-7085
IS - 12
M1 - 470295
ER -