Semantic denoising autoencoders for retinal optical coherence tomography

Research output: Chapter in book/report/conference proceedingConference contributionResearchpeer review

Authors

  • Max Heinrich Laves
  • Sontje Ihler
  • Lüder Alexander Kahrs
  • Tobias Ortmaier

Research Organisations

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Details

Original languageEnglish
Title of host publicationEuropean Conference on Biomedical Optics, ECBO_2019
PublisherOSA - The Optical Society
Number of pages4
ISBN (print)9781510628397
Publication statusPublished - 19 Jul 2019
EventEuropean Conference on Biomedical Optics, ECBO_2019 - Munich, Netherlands
Duration: 23 Jun 201925 Jun 2019

Publication series

NameOptics InfoBase Conference Papers
VolumePart F142-ECBO 2019
ISSN (Print)2162-2701

Abstract

Noise in speckle-prone optical coherence tomography tends to obfuscate important details necessary for medical diagnosis. In this paper, a denoising approach that preserves disease characteristics on retinal optical coherence tomography images in ophthalmology is presented. We propose semantic denoising autoencoders, which combine a convolutional denoising autoencoder with a priorly trained ResNet image classifier as regularizer during training. This promotes the perceptibility of delicate details in the denoised images that are important for diagnosis and filters out only informationless background noise. With our approach, higher peak signal-to-noise ratios with PSNR = 31.0 dB and higher classification performance of F1 = 0.92 can be achieved for denoised images compared to state-of-the-art denoising. It is shown that semantically regularized autoencoders are capable of denoising retinal OCT images without blurring details of diseases.

Keywords

    Computer-aided diagnosis, Image classification, Image enhancement, Machine learning

ASJC Scopus subject areas

Cite this

Semantic denoising autoencoders for retinal optical coherence tomography. / Laves, Max Heinrich; Ihler, Sontje; Kahrs, Lüder Alexander et al.
European Conference on Biomedical Optics, ECBO_2019. OSA - The Optical Society, 2019. 11078_43 (Optics InfoBase Conference Papers; Vol. Part F142-ECBO 2019).

Research output: Chapter in book/report/conference proceedingConference contributionResearchpeer review

Laves, MH, Ihler, S, Kahrs, LA & Ortmaier, T 2019, Semantic denoising autoencoders for retinal optical coherence tomography. in European Conference on Biomedical Optics, ECBO_2019., 11078_43, Optics InfoBase Conference Papers, vol. Part F142-ECBO 2019, OSA - The Optical Society, European Conference on Biomedical Optics, ECBO_2019, Munich, Netherlands, 23 Jun 2019. https://doi.org/10.1117/12.2526936
Laves, M. H., Ihler, S., Kahrs, L. A., & Ortmaier, T. (2019). Semantic denoising autoencoders for retinal optical coherence tomography. In European Conference on Biomedical Optics, ECBO_2019 Article 11078_43 (Optics InfoBase Conference Papers; Vol. Part F142-ECBO 2019). OSA - The Optical Society. https://doi.org/10.1117/12.2526936
Laves MH, Ihler S, Kahrs LA, Ortmaier T. Semantic denoising autoencoders for retinal optical coherence tomography. In European Conference on Biomedical Optics, ECBO_2019. OSA - The Optical Society. 2019. 11078_43. (Optics InfoBase Conference Papers). doi: 10.1117/12.2526936
Laves, Max Heinrich ; Ihler, Sontje ; Kahrs, Lüder Alexander et al. / Semantic denoising autoencoders for retinal optical coherence tomography. European Conference on Biomedical Optics, ECBO_2019. OSA - The Optical Society, 2019. (Optics InfoBase Conference Papers).
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