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  1. 2010

  2. Published

    Statistical aspects of design and validation of microtitre-plate-based linear and non-linear parallel in vitro bioassays

    Zimmermann, H., Gerhard, D., Dingermann, T. & Hothorn, L. A., 12 Jan 2010, In: Biotechnology journal. 5, 1, p. 62-74 13 p.

    Research output: Contribution to journalArticleResearchpeer review

  3. 2009

  4. Published

    New, highly active nonbenzoquinone geldanamycin derivatives by using mutasynthesis

    Eichner, S., Floss, H. G., Sasse, F. & Kirschning, A., 13 Jul 2009, In: ChemBioChem. 10, 11, p. 1801-1805 5 p.

    Research output: Contribution to journalArticleResearchpeer review

  5. External

    The antibiotic ADEP reprogrammes CIpP, switching it from a regulated to an uncontrolled protease

    Kirstein, J., Hoffmann, A., Lilie, H., Schmidt, R., Helga, R. W., Heike, B. O., Mogk, A. & Turgay, K., 26 Mar 2009, In: EMBO molecular medicine. 1, 1, p. 37-49 13 p.

    Research output: Contribution to journalArticleResearchpeer review

  6. 2008

  7. External

    In vivo mutational analysis of the mupirocin gene cluster reveals labile points in the biosynthetic pathway: The "leaky hosepipe" mechanism

    Wu, J., Hothersall, J., Mazzetti, C., O'Connell, Y., Shields, J. A., Rahman, A. S., Cox, R. J., Crosby, J., Simpson, T. J., Thomas, C. M. & Willis, C. L., 16 Jun 2008, In: CHEMBIOCHEM. 9, 9, p. 1500-1508 9 p.

    Research output: Contribution to journalArticleResearchpeer review

  8. Published

    Highly active ansamitocin derivatives: Mutasynthesis using an AHBA-blocked mutant

    Taft, F., Brünjes, M., Floss, H. G., Czempinski, N., Grond, S., Sasse, F. & Kirschning, A., 28 Apr 2008, In: ChemBioChem. 9, 7, p. 1057-1060 4 p.

    Research output: Contribution to journalArticleResearchpeer review

  9. External

    Authentic heterologous expression of the tenellin iterative polyketide synthase nonribosomal peptide synthetase requires cooexpression with an enoyl reductase

    Halo, L. M., Marshall, J. W., Yakasai, A. A., Song, Z., Butts, C. P., Crump, M. P., Heneghan, M., Bailey, A. M., Simpson, T. J., Lazarus, C. M. & Cox, R. J., 3 Mar 2008, In: CHEMBIOCHEM. 9, 4, p. 585-594 10 p.

    Research output: Contribution to journalArticleResearchpeer review

  10. 2007

  11. Published

    An improved synthesis of 4-chlorocoumarin-3-sulfonyl chloride and its reactions with different bidentate nucleophiles to give pyrido[1′, 2′:2,3]- and thiazino[3′,2′:2,3]-1,2,4-thiadiazino[6,5-c] benzopyran-6-one 7,7-dioxides

    Jashari, A., Hey-Hawkins, E., Mikhova, B., Draeger, G. & Popovski, E., Aug 2007, In: MOLECULES. 12, 8, p. 2017-2028 12 p.

    Research output: Contribution to journalArticleResearchpeer review

  12. External

    Biosynthesis of the 2-pyridone tenellin in the insect pathogenic fungus Beauveria bassiana

    Eley, K. L., Halo, L. M., Song, Z., Powles, H., Cox, R. J., Bailey, A. M., Lazarus, C. M. & Simpson, T. J., 12 Feb 2007, In: CHEMBIOCHEM. 8, 3, p. 289-297 9 p.

    Research output: Contribution to journalArticleResearchpeer review

  13. External

    Synthesis of [1,2-13C2,15N]-L-homoserine and its incorporation by the PKS-NRPS system of Fusarium moniliforme into the mycotoxin fusarin C

    Rees, D. O., Bushby, N., Cox, R. J., Harding, J. R., Simpson, T. J. & Willis, C. L., 2007, In: CHEMBIOCHEM. 8, 1, p. 46-50 5 p.

    Research output: Contribution to journalArticleResearchpeer review

  14. 2006

  15. External

    Catalytic relationships between type I and type II iterative polyketide synthases: The Aspergillus parasiticus norsolorinic acid synthase

    Ma, Y., Smith, L. H., Cox, R. J., Beltran-Alvarez, P., Arthur, C. J. & Simpson, T. J., 1 Dec 2006, In: CHEMBIOCHEM. 7, 12, p. 1951-1958 8 p.

    Research output: Contribution to journalArticleResearchpeer review

  16. Published

    Determination of the cryptic stereochemistry of the first PKS chain-extension step in ansamitocin biosynthesis by Actinosynnema pretiosum

    Kubota, T., Brünjes, M., Frenzel, T., Xu, J., Kirschning, A. & Floss, H. G., 27 Jul 2006, In: ChemBioChem. 7, 8, p. 1221-1225 5 p.

    Research output: Contribution to journalArticleResearchpeer review

  17. External

    The Malonyl Transferase Activity of Type II Polyketide Synthase Acyl Carrier Proteins

    Arthur, C. J., Szafranska, A. E., Long, J., Mills, J., Cox, R. J., Findlow, S. C., Simpson, T. J., Crump, M. P. & Crosby, J., 1 Jun 2006, In: Chemistry and Biology. 13, 6, p. 587-596 10 p.

    Research output: Contribution to journalArticleResearchpeer review

  18. 2005

  19. External

    Design, synthesis and analysis of inhibitors of bacterial aspartate semialdehyde dehydrogenase

    Cox, R. J., Gibson, J. S. & Hadfield, A. T., 1 Dec 2005, In: CHEMBIOCHEM. 6, 12, p. 2255-2260 6 p.

    Research output: Contribution to journalArticleResearchpeer review

  20. External

    A fragment-based approach to understanding inhibition of 1-deoxy-D-xylulose-5-phosphate reductoisomerase

    Mercklé, L., De Andrés-Gómez, A., Dick, B., Cox, R. J. & Godfrey, C. R. A., 1 Oct 2005, In: CHEMBIOCHEM. 6, 10, p. 1866-1874 9 p.

    Research output: Contribution to journalArticleResearchpeer review

  21. Published

    An enzyme module system for the synthesis of dTDP-activated deoxysugars from dTMP and sucrose

    Elling, L., Rupprath, C., Günther, N., Römer, U., Verseck, S., Weingarten, P., Dräger, G., Kirschning, A. & Piepersberg, W., 5 Aug 2005, In: ChemBioChem. 6, 8, p. 1423-1430 8 p.

    Research output: Contribution to journalArticleResearchpeer review

  22. 2004

  23. External

    Fusarin C biosynthesis in Fusarium moniliforme and Fusarium venenatum

    Song, Z., Cox, R. J., Lazarus, C. M. & Simpson, T. J., 6 Sept 2004, In: CHEMBIOCHEM. 5, 9, p. 1196-1203 8 p.

    Research output: Contribution to journalArticleResearchpeer review

  24. Published

    Rational saccharide extension by using the natural product glycosyltransferase LanGT4

    Hoffmeister, D., Weber, M., Dräger, G., Ichinose, K., Dürr, C. & Bechthold, A., 5 Mar 2004, In: CHEMBIOCHEM. 5, 3, p. 369-371 3 p.

    Research output: Contribution to journalArticleResearchpeer review

  25. 2002

  26. External

    Aspartyl phosphonates and phosphoramidates: The first synthetic inhibitors of bacterial aspartate-semialdehyde dehydrogenase

    Cox, R. J., Gibson, J. S., Belén, M. & Martín, M., 1 Dec 2002, In: CHEMBIOCHEM. 3, 9, p. 874-886 13 p.

    Research output: Contribution to journalArticleResearchpeer review

  27. External

    Synthesis and characterisation of acyl carrier protein bound polyketide analogues

    Arthur, C., Cox, R. J., Crosby, J., Rahman, M. M., Simpson, T. J., Soulas, F., Spogli, R., Szafranska, A. E., Westcott, J. & Winfield, C. J., 1 Mar 2002, In: CHEMBIOCHEM. 3, 2-3, p. 253-257 5 p.

    Research output: Contribution to journalArticleResearchpeer review

  28. 2001

  29. Published

    The Chemstry and Biology of Ratjadone

    Kalesse, M., Christmann, M., Bhatt, U., Quitschalle, M., Claus, E., Saeed, A., Burzlaff, A., Kasper, C., Haustedt, L. O., Hofer, E., Scheper, T. & Beil, W., 10 Sept 2001, In: CHEMBIOCHEM. 2, 9, p. 709-714 6 p.

    Research output: Contribution to journalArticleResearchpeer review