Rheuma-VOR study: Optimising healthcare of rheumatic diseases by multiprofessional coordinating centres

Research output: Contribution to journalArticleResearchpeer review

Authors

  • Matthias Dreher
  • Torsten Witte
  • Kirsten Hoeper
  • Gunter Assmann
  • Fabian Proft
  • Denis Poddubnyy
  • Niels Murawski
  • Konstantinos Triantafyllias
  • Marlon Grodd
  • Erika Graf
  • Urs A. Fichtner
  • Harald Binder
  • Jan Zeidler
  • Juliana Rachel Hoeper
  • Johanna Callhoff
  • Kirsten Karberg
  • Anna Trautwein
  • Dativa Tibyampansha
  • Leszek Wojnowski
  • Reinhold E. Schmidt
  • Andreas Schwarting

External Research Organisations

  • Johannes Gutenberg University Mainz
  • Hannover Medical School (MHH)
  • Center for Rheumatology Lower Saxony e.V.
  • Johannes Wesling Klinikum Minden
  • Charité - Universitätsmedizin Berlin
  • Saarland University
  • Center for Rheumatology Rhineland-Palatinate
  • Universitätsklinikum Freiburg
  • German Rheumatism Research Centre Berlin (DRFZ)
  • Center for Rheumatology
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Details

Original languageEnglish
Article numberard-2023-224205
Pages (from-to)184-193
Number of pages10
JournalAnnals of the rheumatic diseases
Volume83
Issue number2
Early online date27 Oct 2023
Publication statusPublished - 27 Oct 2023

Abstract

Objectives: Early diagnosis of inflammatory arthritis is critical to prevent joint damage and functional incapacities. However, the discrepancy between recommendations of early diagnosis and reality is remarkable. The Rheuma-VOR study aimed to improve the time to diagnosis of patients with early arthritis by coordinating cooperation between primary care physicians, specialists and patients in Germany. Methods: This prospective non-randomised multicentre study involved 2340 primary care physicians, 72 rheumatologists, 4 university hospitals and 4 rheumatology centres in 4 German Federal States. The two coprimary endpoints (time to diagnosis and screening performance of primary care physicians) were evaluated for early versus late implementation phase. Additionally, time to diagnosis and secondary endpoints (decrease of disease activity, increase in quality of life and overall well-being, improvement of fatigue, depression, functional ability, and work ability, reduction in drug and medical costs and hospitalisation) were compared with a reference cohort of the German Rheumatism Research Centre (DRFZ) reflecting standard care. Results: A total of 7049 patients were enrolled in the coordination centres and 1537 patients were diagnosed with a rheumatic disease and consented to further participation. A follow-up consultation after 1 year was realised in 592 patients. The time to diagnosis endpoint and the secondary endpoints were met. In addition, the calculation of cost-effectiveness shows that Rheuma-VOR has a dominant cost-benefit ratio compared with standard care. Discussion: Rheuma-VOR has shown an improvement in rheumatological care, patient-reported outcome parameters and cost savings by coordinating the cooperation of primary care physicians, rheumatologists and patients, in a nationwide approach.

Keywords

    arthritis, psoriatic, arthritis, rheumatoid, health services research, spondylitis, ankylosing

ASJC Scopus subject areas

Cite this

Rheuma-VOR study: Optimising healthcare of rheumatic diseases by multiprofessional coordinating centres. / Dreher, Matthias; Witte, Torsten; Hoeper, Kirsten et al.
In: Annals of the rheumatic diseases, Vol. 83, No. 2, ard-2023-224205, 27.10.2023, p. 184-193.

Research output: Contribution to journalArticleResearchpeer review

Dreher, M, Witte, T, Hoeper, K, Assmann, G, Proft, F, Poddubnyy, D, Murawski, N, Triantafyllias, K, Grodd, M, Graf, E, Fichtner, UA, Binder, H, Zeidler, J, Hoeper, JR, Callhoff, J, Karberg, K, Trautwein, A, Tibyampansha, D, Wojnowski, L, Schmidt, RE & Schwarting, A 2023, 'Rheuma-VOR study: Optimising healthcare of rheumatic diseases by multiprofessional coordinating centres', Annals of the rheumatic diseases, vol. 83, no. 2, ard-2023-224205, pp. 184-193. https://doi.org/10.1136/ard-2023-224205
Dreher, M., Witte, T., Hoeper, K., Assmann, G., Proft, F., Poddubnyy, D., Murawski, N., Triantafyllias, K., Grodd, M., Graf, E., Fichtner, U. A., Binder, H., Zeidler, J., Hoeper, J. R., Callhoff, J., Karberg, K., Trautwein, A., Tibyampansha, D., Wojnowski, L., ... Schwarting, A. (2023). Rheuma-VOR study: Optimising healthcare of rheumatic diseases by multiprofessional coordinating centres. Annals of the rheumatic diseases, 83(2), 184-193. Article ard-2023-224205. https://doi.org/10.1136/ard-2023-224205
Dreher M, Witte T, Hoeper K, Assmann G, Proft F, Poddubnyy D et al. Rheuma-VOR study: Optimising healthcare of rheumatic diseases by multiprofessional coordinating centres. Annals of the rheumatic diseases. 2023 Oct 27;83(2):184-193. ard-2023-224205. Epub 2023 Oct 27. doi: 10.1136/ard-2023-224205
Dreher, Matthias ; Witte, Torsten ; Hoeper, Kirsten et al. / Rheuma-VOR study : Optimising healthcare of rheumatic diseases by multiprofessional coordinating centres. In: Annals of the rheumatic diseases. 2023 ; Vol. 83, No. 2. pp. 184-193.
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abstract = "Objectives: Early diagnosis of inflammatory arthritis is critical to prevent joint damage and functional incapacities. However, the discrepancy between recommendations of early diagnosis and reality is remarkable. The Rheuma-VOR study aimed to improve the time to diagnosis of patients with early arthritis by coordinating cooperation between primary care physicians, specialists and patients in Germany. Methods: This prospective non-randomised multicentre study involved 2340 primary care physicians, 72 rheumatologists, 4 university hospitals and 4 rheumatology centres in 4 German Federal States. The two coprimary endpoints (time to diagnosis and screening performance of primary care physicians) were evaluated for early versus late implementation phase. Additionally, time to diagnosis and secondary endpoints (decrease of disease activity, increase in quality of life and overall well-being, improvement of fatigue, depression, functional ability, and work ability, reduction in drug and medical costs and hospitalisation) were compared with a reference cohort of the German Rheumatism Research Centre (DRFZ) reflecting standard care. Results: A total of 7049 patients were enrolled in the coordination centres and 1537 patients were diagnosed with a rheumatic disease and consented to further participation. A follow-up consultation after 1 year was realised in 592 patients. The time to diagnosis endpoint and the secondary endpoints were met. In addition, the calculation of cost-effectiveness shows that Rheuma-VOR has a dominant cost-benefit ratio compared with standard care. Discussion: Rheuma-VOR has shown an improvement in rheumatological care, patient-reported outcome parameters and cost savings by coordinating the cooperation of primary care physicians, rheumatologists and patients, in a nationwide approach.",
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author = "Matthias Dreher and Torsten Witte and Kirsten Hoeper and Gunter Assmann and Fabian Proft and Denis Poddubnyy and Niels Murawski and Konstantinos Triantafyllias and Marlon Grodd and Erika Graf and Fichtner, {Urs A.} and Harald Binder and Jan Zeidler and Hoeper, {Juliana Rachel} and Johanna Callhoff and Kirsten Karberg and Anna Trautwein and Dativa Tibyampansha and Leszek Wojnowski and Schmidt, {Reinhold E.} and Andreas Schwarting",
note = "Funding Information: We dedicate this article to our beloved colleague Prof. Reinhold E. Schmidt, who was one of the driving forces behind the project and who sadly passed away unexpectedly two years ago. Rheuma-VOR was funded by the Innovation Fund at the Federal Joint Committee (G-BA) from 2017 to 2021. The funding has no influence on the study. Funding code: 01NVF16029. Preliminary results of the different Rheuma-VOR substudies were presented at national (DGRh) and international (EULAR) conferences. The authors would like to thank the participating rheumatological practices, the Deutsche Rheumaliga, the Rheumaliga Landesverband of the federal states, the Deutsche Vereinigung Morbus Bechterew e.V., and the participants for the excellent cooperation. Funding Information: Rheuma-VOR was funded by the Innovation Fund at the Federal Joint Committee (G-BA) from 2017 to 2021. Funding code: 01NVF16029.",
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T2 - Optimising healthcare of rheumatic diseases by multiprofessional coordinating centres

AU - Dreher, Matthias

AU - Witte, Torsten

AU - Hoeper, Kirsten

AU - Assmann, Gunter

AU - Proft, Fabian

AU - Poddubnyy, Denis

AU - Murawski, Niels

AU - Triantafyllias, Konstantinos

AU - Grodd, Marlon

AU - Graf, Erika

AU - Fichtner, Urs A.

AU - Binder, Harald

AU - Zeidler, Jan

AU - Hoeper, Juliana Rachel

AU - Callhoff, Johanna

AU - Karberg, Kirsten

AU - Trautwein, Anna

AU - Tibyampansha, Dativa

AU - Wojnowski, Leszek

AU - Schmidt, Reinhold E.

AU - Schwarting, Andreas

N1 - Funding Information: We dedicate this article to our beloved colleague Prof. Reinhold E. Schmidt, who was one of the driving forces behind the project and who sadly passed away unexpectedly two years ago. Rheuma-VOR was funded by the Innovation Fund at the Federal Joint Committee (G-BA) from 2017 to 2021. The funding has no influence on the study. Funding code: 01NVF16029. Preliminary results of the different Rheuma-VOR substudies were presented at national (DGRh) and international (EULAR) conferences. The authors would like to thank the participating rheumatological practices, the Deutsche Rheumaliga, the Rheumaliga Landesverband of the federal states, the Deutsche Vereinigung Morbus Bechterew e.V., and the participants for the excellent cooperation. Funding Information: Rheuma-VOR was funded by the Innovation Fund at the Federal Joint Committee (G-BA) from 2017 to 2021. Funding code: 01NVF16029.

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N2 - Objectives: Early diagnosis of inflammatory arthritis is critical to prevent joint damage and functional incapacities. However, the discrepancy between recommendations of early diagnosis and reality is remarkable. The Rheuma-VOR study aimed to improve the time to diagnosis of patients with early arthritis by coordinating cooperation between primary care physicians, specialists and patients in Germany. Methods: This prospective non-randomised multicentre study involved 2340 primary care physicians, 72 rheumatologists, 4 university hospitals and 4 rheumatology centres in 4 German Federal States. The two coprimary endpoints (time to diagnosis and screening performance of primary care physicians) were evaluated for early versus late implementation phase. Additionally, time to diagnosis and secondary endpoints (decrease of disease activity, increase in quality of life and overall well-being, improvement of fatigue, depression, functional ability, and work ability, reduction in drug and medical costs and hospitalisation) were compared with a reference cohort of the German Rheumatism Research Centre (DRFZ) reflecting standard care. Results: A total of 7049 patients were enrolled in the coordination centres and 1537 patients were diagnosed with a rheumatic disease and consented to further participation. A follow-up consultation after 1 year was realised in 592 patients. The time to diagnosis endpoint and the secondary endpoints were met. In addition, the calculation of cost-effectiveness shows that Rheuma-VOR has a dominant cost-benefit ratio compared with standard care. Discussion: Rheuma-VOR has shown an improvement in rheumatological care, patient-reported outcome parameters and cost savings by coordinating the cooperation of primary care physicians, rheumatologists and patients, in a nationwide approach.

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