Details
| Original language | English |
|---|---|
| Pages (from-to) | 8972-8975 |
| Number of pages | 4 |
| Journal | Chemical communications |
| Volume | 54 |
| Issue number | 65 |
| Early online date | 28 Jun 2018 |
| Publication status | Published - 21 Aug 2018 |
Abstract
Fast (>100 kHz) magic angle spinning solid-state NMR allows combining high-sensitive proton detection with the absence of an intrinsic molecular weight limit. Using this technique we observe for the first time narrow 1H RNA resonances and assign nucleotide spin systems with only 200 μg of uniformly 13C,15N-labelled RNA.
ASJC Scopus subject areas
- Chemical Engineering(all)
- Catalysis
- Materials Science(all)
- Electronic, Optical and Magnetic Materials
- Materials Science(all)
- Ceramics and Composites
- Chemistry(all)
- General Chemistry
- Materials Science(all)
- Surfaces, Coatings and Films
- Materials Science(all)
- Metals and Alloys
- Materials Science(all)
- Materials Chemistry
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In: Chemical communications, Vol. 54, No. 65, 21.08.2018, p. 8972-8975.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Rapid access to RNA resonances by proton-detected solid-state NMR at >100 kHz MAS
AU - Marchanka, Alexander
AU - Stanek, Jan
AU - Pintacuda, Guido
AU - Carlomagno, Teresa
N1 - Funding Information: TC was supported by the DFG (CA 294/10-1), GP by the ERC (ERC-2015-CoG GA 648974), and JS by a Marie Skłodowska-Curie fellowship (GA 661799 COMPLEX-FAST-MAS). The work was co-funded by Instruct, a part of the ESFRI, and supported by national member subscriptions, by CNRS (IR-RMN FR3050) and by the EU-project iNext (GA 653706).
PY - 2018/8/21
Y1 - 2018/8/21
N2 - Fast (>100 kHz) magic angle spinning solid-state NMR allows combining high-sensitive proton detection with the absence of an intrinsic molecular weight limit. Using this technique we observe for the first time narrow 1H RNA resonances and assign nucleotide spin systems with only 200 μg of uniformly 13C,15N-labelled RNA.
AB - Fast (>100 kHz) magic angle spinning solid-state NMR allows combining high-sensitive proton detection with the absence of an intrinsic molecular weight limit. Using this technique we observe for the first time narrow 1H RNA resonances and assign nucleotide spin systems with only 200 μg of uniformly 13C,15N-labelled RNA.
UR - http://www.scopus.com/inward/record.url?scp=85051466179&partnerID=8YFLogxK
U2 - 10.1039/c8cc04437f
DO - 10.1039/c8cc04437f
M3 - Article
C2 - 29974085
AN - SCOPUS:85051466179
VL - 54
SP - 8972
EP - 8975
JO - Chemical communications
JF - Chemical communications
SN - 1359-7345
IS - 65
ER -