Details
| Original language | English |
|---|---|
| Article number | 100692 |
| Journal | Current Opinion in Green and Sustainable Chemistry |
| Volume | 38 |
| Early online date | 31 Aug 2022 |
| Publication status | Published - Dec 2022 |
Abstract
In the last ten years, the number of publications related to process intensification (PI) has been quadrupled. This increasing interest that created many innovations can be found not only in chemo-catalytic processes but has also reached the field of enzymatic processes. The recent scientific and technological advances in bioprocess intensification have been dedicated to improving the use of enzymes in selective oxidative reactions, obtaining more environmentally friendly and resource efficient applications. In this mini-review, we provide an overview of the different PI definitions, and recent studies focusing on intensification of oxidative biocatalytic reactions regarding (i) non-conventional media, (ii) process data and analytics, (iii) reactor engineering, and (iv) downstream processing. Remarking how the advances of other fields can be used for process intensification and for obtaining new goals (e.g., PI 4.0). Model-based simulations and new sensor technologies can guarantee optimal and more automated processes with new reactor designs, together with the use of non-conventional media and enzyme immobilization, to intensify biocatalytic oxidation processes.
Keywords
- Biocatalysis, Downstream processing, Non-conventional media, Oxidative enzymes, Process data, Reactor engineering
ASJC Scopus subject areas
- Chemical Engineering(all)
- Catalysis
- Chemistry(all)
- Chemistry (miscellaneous)
- Environmental Science(all)
- Waste Management and Disposal
- Chemical Engineering(all)
- Process Chemistry and Technology
- Environmental Science(all)
- Management, Monitoring, Policy and Law
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In: Current Opinion in Green and Sustainable Chemistry, Vol. 38, 100692, 12.2022.
Research output: Contribution to journal › Review article › Research › peer review
}
TY - JOUR
T1 - Process intensification in oxidative biocatalysis
AU - Vernet, Guillem
AU - Hobisch, Markus
AU - Kara, Selin
N1 - Funding Information: Aarhus University Research Foundation (AUFF, Aarhus Universitets Forskningsfond) is acknowledged for the financial support.
PY - 2022/12
Y1 - 2022/12
N2 - In the last ten years, the number of publications related to process intensification (PI) has been quadrupled. This increasing interest that created many innovations can be found not only in chemo-catalytic processes but has also reached the field of enzymatic processes. The recent scientific and technological advances in bioprocess intensification have been dedicated to improving the use of enzymes in selective oxidative reactions, obtaining more environmentally friendly and resource efficient applications. In this mini-review, we provide an overview of the different PI definitions, and recent studies focusing on intensification of oxidative biocatalytic reactions regarding (i) non-conventional media, (ii) process data and analytics, (iii) reactor engineering, and (iv) downstream processing. Remarking how the advances of other fields can be used for process intensification and for obtaining new goals (e.g., PI 4.0). Model-based simulations and new sensor technologies can guarantee optimal and more automated processes with new reactor designs, together with the use of non-conventional media and enzyme immobilization, to intensify biocatalytic oxidation processes.
AB - In the last ten years, the number of publications related to process intensification (PI) has been quadrupled. This increasing interest that created many innovations can be found not only in chemo-catalytic processes but has also reached the field of enzymatic processes. The recent scientific and technological advances in bioprocess intensification have been dedicated to improving the use of enzymes in selective oxidative reactions, obtaining more environmentally friendly and resource efficient applications. In this mini-review, we provide an overview of the different PI definitions, and recent studies focusing on intensification of oxidative biocatalytic reactions regarding (i) non-conventional media, (ii) process data and analytics, (iii) reactor engineering, and (iv) downstream processing. Remarking how the advances of other fields can be used for process intensification and for obtaining new goals (e.g., PI 4.0). Model-based simulations and new sensor technologies can guarantee optimal and more automated processes with new reactor designs, together with the use of non-conventional media and enzyme immobilization, to intensify biocatalytic oxidation processes.
KW - Biocatalysis
KW - Downstream processing
KW - Non-conventional media
KW - Oxidative enzymes
KW - Process data
KW - Reactor engineering
UR - http://www.scopus.com/inward/record.url?scp=85140963471&partnerID=8YFLogxK
U2 - 10.1016/j.cogsc.2022.100692
DO - 10.1016/j.cogsc.2022.100692
M3 - Review article
AN - SCOPUS:85140963471
VL - 38
JO - Current Opinion in Green and Sustainable Chemistry
JF - Current Opinion in Green and Sustainable Chemistry
SN - 2452-2236
M1 - 100692
ER -