Details
| Original language | English |
|---|---|
| Pages (from-to) | 2010-2026 |
| Number of pages | 17 |
| Journal | Organic and Biomolecular Chemistry |
| Volume | 5 |
| Issue number | 13 |
| Publication status | Published - 1 Jan 2007 |
| Externally published | Yes |
Abstract
Fungi produce a wide variety of biologically active compounds. Among these, the polyketides form a large and structurally diverse group. These compounds are synthesised by highly programmed and very large iterative multifunctional proteins, the polyketide synthases, with nm dimensions. This review outlines the current state of knowledge regarding the links between gene sequence, protein architecture and biosynthetic programming for fungal polyketide synthases.
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Biochemistry
- Chemistry(all)
- Physical and Theoretical Chemistry
- Chemistry(all)
- Organic Chemistry
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In: Organic and Biomolecular Chemistry, Vol. 5, No. 13, 01.01.2007, p. 2010-2026.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Polyketides, proteins and genes in fungi
T2 - Programmed nano-machines begin to reveal their secrets
AU - Cox, Russell J.
PY - 2007/1/1
Y1 - 2007/1/1
N2 - Fungi produce a wide variety of biologically active compounds. Among these, the polyketides form a large and structurally diverse group. These compounds are synthesised by highly programmed and very large iterative multifunctional proteins, the polyketide synthases, with nm dimensions. This review outlines the current state of knowledge regarding the links between gene sequence, protein architecture and biosynthetic programming for fungal polyketide synthases.
AB - Fungi produce a wide variety of biologically active compounds. Among these, the polyketides form a large and structurally diverse group. These compounds are synthesised by highly programmed and very large iterative multifunctional proteins, the polyketide synthases, with nm dimensions. This review outlines the current state of knowledge regarding the links between gene sequence, protein architecture and biosynthetic programming for fungal polyketide synthases.
UR - http://www.scopus.com/inward/record.url?scp=34250790717&partnerID=8YFLogxK
U2 - 10.1039/b704420h
DO - 10.1039/b704420h
M3 - Article
C2 - 17581644
AN - SCOPUS:34250790717
VL - 5
SP - 2010
EP - 2026
JO - Organic and Biomolecular Chemistry
JF - Organic and Biomolecular Chemistry
SN - 1477-0520
IS - 13
ER -