Polyanionic multivalent macromolecules for intracellular targeting of proliferation and protein synthesis

Research output: Patent

Inventors

  • Kai Licha (Inventor)
  • Michael Schirner (Inventor)
  • Pia Welker (Inventor)
  • Rainer Haag (Inventor)
  • Marie Weinhart (Inventor)
  • Florian Paulus (Inventor)

External Research Organisations

  • Freie Universität Berlin (FU Berlin)
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Details

Original languageEnglish
Patent numberWO2011095311A1
IPCA61K47/48,C08G83/00,A61K49/12,A61K49/00
Priority date2 Mar 2010
Filing date31 Jan 2011
Publication statusPublished - 11 Aug 2011
Externally publishedYes

Abstract

The present invention relates generally to methods and compositions for targeting of intracellular molecules involved in proliferation and protein synthesis of activated cells using polyanionic multivalent macromolecules. In particular aspect, multiple sulfate groups linked to polyol are specifically targeted to the cytoplasm and nucleus of proliferating and activated cells. The invention further comprises novel polyanionic macromolecular compounds and formulations.

Cite this

Polyanionic multivalent macromolecules for intracellular targeting of proliferation and protein synthesis. / Licha, Kai (Inventor); Schirner, Michael (Inventor); Welker, Pia (Inventor) et al.
Patent No.: WO2011095311A1. Aug 11, 2011.

Research output: Patent

Licha K, Schirner M, Welker P, Haag R, Weinhart M, Paulus F, inventors. Polyanionic multivalent macromolecules for intracellular targeting of proliferation and protein synthesis. WO2011095311A1. 2011 Aug 11.
Licha, Kai (Inventor) ; Schirner, Michael (Inventor) ; Welker, Pia (Inventor) et al. / Polyanionic multivalent macromolecules for intracellular targeting of proliferation and protein synthesis. Patent No.: WO2011095311A1. Aug 11, 2011.
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