Details
| Original language | English |
|---|---|
| Pages (from-to) | 84-89 |
| Number of pages | 6 |
| Journal | Phytochemistry letters |
| Volume | 6 |
| Issue number | 1 |
| Publication status | Published - 1 Feb 2013 |
| Externally published | Yes |
Abstract
Three new phenolic compounds, sorlanin (4-(3-(hydroxymethyl)-5-methoxy-7- phenyl-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)-2-methoxyphenol, 1), sorbanin (2-((3,5-dimethoxy-[1,1′-biphenyl]-4-yl)oxy)-1-(4-hydroxy-3-methoxyphenyl) propane-1,3-diol, 2) and sorbalanin (4-(3-(hydroxymethyl)-5,6-dimethoxy-2,3- dihydrobenzo[b][1,4]dioxino[2,3-g]benzofuran-2-yl)-2-methoxyphenol, 3), together with eight known compounds, polystachyol (4), isolariciresinol (5), dihydrodehydrodiconiferyl alcohol (6), tuberculatin (7), ovafolinin E (8), aucuparin (9), 2′-methoxyaucuparin (10), and tetracosyl-3-(3,4- dihydroxyphenyl)acrylate (11), were isolated from Sorbus lanata. The structures of these phytoconstituents were elucidated through extensive spectroscopic techniques, including UV, IR, 1D and 2D NMR, ESI-MS and HRESI-MS experiments. All the compounds except 9 and 10 were isolated for the first time from the genus Sorbus. The isolated compounds were also tested in DPPH radical scavenging reaction where compounds 6, 7, 10 and 11 showed significant activities with IC50 values of 9.2, 11.7, 23.0 and 33.7 μM, respectively.
Keywords
- DPPH radical scavenging activity, HPLC separations, Phenolic compounds, Sorbus lanata
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Biotechnology
- Biochemistry, Genetics and Molecular Biology(all)
- Biochemistry
- Agricultural and Biological Sciences(all)
- Agronomy and Crop Science
- Agricultural and Biological Sciences(all)
- Plant Science
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In: Phytochemistry letters, Vol. 6, No. 1, 01.02.2013, p. 84-89.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Phytochemicals from the stem wood of Sorbus lanata (D. Don.) Schauer
AU - Uddin, Ghias
AU - Latif, Abdul
AU - Arfan, Mohammad
AU - Ali, Mumtaz
AU - Hussain, Syed Hamid
AU - Simpson, Thomas J.
AU - Cox, Russel J.
AU - Choudhary, Muhammad Iqbal
N1 - Funding information: We are thankful to the Higher Education Commission of Pakistan for giving financial support through Indigenous 5000 Fellowships Program and International Research Support Initiative Program (IRSIP) to Mr. Abdul Latif (Co-author). We are also grateful to Prof. Tom Simpson, Prof. Russell J. Cox and Prof. Craig Butts of the University of Bristol (UK) for providing technical facilities and guidance throughout the completion of this work.
PY - 2013/2/1
Y1 - 2013/2/1
N2 - Three new phenolic compounds, sorlanin (4-(3-(hydroxymethyl)-5-methoxy-7- phenyl-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)-2-methoxyphenol, 1), sorbanin (2-((3,5-dimethoxy-[1,1′-biphenyl]-4-yl)oxy)-1-(4-hydroxy-3-methoxyphenyl) propane-1,3-diol, 2) and sorbalanin (4-(3-(hydroxymethyl)-5,6-dimethoxy-2,3- dihydrobenzo[b][1,4]dioxino[2,3-g]benzofuran-2-yl)-2-methoxyphenol, 3), together with eight known compounds, polystachyol (4), isolariciresinol (5), dihydrodehydrodiconiferyl alcohol (6), tuberculatin (7), ovafolinin E (8), aucuparin (9), 2′-methoxyaucuparin (10), and tetracosyl-3-(3,4- dihydroxyphenyl)acrylate (11), were isolated from Sorbus lanata. The structures of these phytoconstituents were elucidated through extensive spectroscopic techniques, including UV, IR, 1D and 2D NMR, ESI-MS and HRESI-MS experiments. All the compounds except 9 and 10 were isolated for the first time from the genus Sorbus. The isolated compounds were also tested in DPPH radical scavenging reaction where compounds 6, 7, 10 and 11 showed significant activities with IC50 values of 9.2, 11.7, 23.0 and 33.7 μM, respectively.
AB - Three new phenolic compounds, sorlanin (4-(3-(hydroxymethyl)-5-methoxy-7- phenyl-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)-2-methoxyphenol, 1), sorbanin (2-((3,5-dimethoxy-[1,1′-biphenyl]-4-yl)oxy)-1-(4-hydroxy-3-methoxyphenyl) propane-1,3-diol, 2) and sorbalanin (4-(3-(hydroxymethyl)-5,6-dimethoxy-2,3- dihydrobenzo[b][1,4]dioxino[2,3-g]benzofuran-2-yl)-2-methoxyphenol, 3), together with eight known compounds, polystachyol (4), isolariciresinol (5), dihydrodehydrodiconiferyl alcohol (6), tuberculatin (7), ovafolinin E (8), aucuparin (9), 2′-methoxyaucuparin (10), and tetracosyl-3-(3,4- dihydroxyphenyl)acrylate (11), were isolated from Sorbus lanata. The structures of these phytoconstituents were elucidated through extensive spectroscopic techniques, including UV, IR, 1D and 2D NMR, ESI-MS and HRESI-MS experiments. All the compounds except 9 and 10 were isolated for the first time from the genus Sorbus. The isolated compounds were also tested in DPPH radical scavenging reaction where compounds 6, 7, 10 and 11 showed significant activities with IC50 values of 9.2, 11.7, 23.0 and 33.7 μM, respectively.
KW - DPPH radical scavenging activity
KW - HPLC separations
KW - Phenolic compounds
KW - Sorbus lanata
UR - http://www.scopus.com/inward/record.url?scp=84870771206&partnerID=8YFLogxK
U2 - 10.1016/j.phytol.2012.10.002
DO - 10.1016/j.phytol.2012.10.002
M3 - Article
AN - SCOPUS:84870771206
VL - 6
SP - 84
EP - 89
JO - Phytochemistry letters
JF - Phytochemistry letters
SN - 1874-3900
IS - 1
ER -