Details
| Original language | English |
|---|---|
| Pages (from-to) | 1305-1308 |
| Number of pages | 4 |
| Journal | Chemical communications |
| Volume | 60 |
| Issue number | 10 |
| Publication status | Published - 27 Dec 2023 |
Abstract
We present the application of a photonic silicon chip-based optical sensor system for expeditious and phenotypic antifungal susceptibility testing. This label-free diagnostic assay optically monitors the growth of Candida auris at varying antifungal concentrations on a microwell-structured silicon chip in real-time, and antifungal susceptibility is detected within 6 h, four times faster than in the current gold standard method.
ASJC Scopus subject areas
- Materials Science(all)
- Electronic, Optical and Magnetic Materials
- Chemical Engineering(all)
- Catalysis
- Materials Science(all)
- Ceramics and Composites
- Chemistry(all)
- Materials Science(all)
- Surfaces, Coatings and Films
- Materials Science(all)
- Metals and Alloys
- Materials Science(all)
- Materials Chemistry
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In: Chemical communications, Vol. 60, No. 10, 27.12.2023, p. 1305-1308.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Photonic Si microwell architectures for rapid antifungal susceptibility determination of Candida auris
AU - Heuer, Christopher
AU - Jiang, Xin
AU - Ron, Gali
AU - Ternyak, Orna
AU - Scheper, Thomas
AU - Bahnemann, Janina
AU - Segal, Ester
N1 - Funding Information: This work was supported by the Israel Science Foundation (grant No. 2458/21). We also acknowledge funding by the German Research Foundation (DFG) via the Emmy Noether program (project ID346772917), and grant SCHE 279/32-2, as well as by the VolkswagenStiftung via the program ‘‘Niedersa¨chsisches Vorab: Research Cooperation Lower Saxony— Israel’’. The authors thank the staff of the Micro- and Nanofabrication and Printing Unit (MNFPU) at the Technion for the fabrication of the photonic silicon chips.
PY - 2023/12/27
Y1 - 2023/12/27
N2 - We present the application of a photonic silicon chip-based optical sensor system for expeditious and phenotypic antifungal susceptibility testing. This label-free diagnostic assay optically monitors the growth of Candida auris at varying antifungal concentrations on a microwell-structured silicon chip in real-time, and antifungal susceptibility is detected within 6 h, four times faster than in the current gold standard method.
AB - We present the application of a photonic silicon chip-based optical sensor system for expeditious and phenotypic antifungal susceptibility testing. This label-free diagnostic assay optically monitors the growth of Candida auris at varying antifungal concentrations on a microwell-structured silicon chip in real-time, and antifungal susceptibility is detected within 6 h, four times faster than in the current gold standard method.
UR - http://www.scopus.com/inward/record.url?scp=85182365163&partnerID=8YFLogxK
U2 - 10.1039/d3cc04446g
DO - 10.1039/d3cc04446g
M3 - Article
C2 - 38197155
AN - SCOPUS:85182365163
VL - 60
SP - 1305
EP - 1308
JO - Chemical communications
JF - Chemical communications
SN - 1359-7345
IS - 10
ER -