Details
| Original language | English |
|---|---|
| Pages (from-to) | 743-748 |
| Number of pages | 6 |
| Journal | Laser physics |
| Volume | 13 |
| Issue number | 5 |
| Publication status | Published - 1 May 2003 |
Abstract
Focusing of femtosecond laser pulses into transparent media, such as corneal tissue, leads to an optical breakdown via nonlinear absorption and cutting effects inside the tissue. Due to these nonlinear absorption processes, nearly all kinds of material can be processed by the laser, even inside the bulk of the material. The corresponding energy threshold for achieving such a cutting effect is lowered for fs pulses by several orders of magnitude as compared with ps or ns pulses. Thus, mechanical and thermal effects on the surrounding tissue can be reduced to a minimum. Based on these small side effects, precision in the μm range at cutting in biological tissue, especially in transparent corneal samples of the eye, can be achieved. Therefore, corneal flaps and lenticules for refractive surgery were created in ex vivo and in vivo eyes. The treated eyes showed the possibility of highly precise dissection and, in the case of living tissue, mild woundhealing reactions comparable to what is known from common laser procedures. Moreover, the use of the fs laser offers new possibilities in the cutting geometry that can be useful in fields of keratoplasty.
ASJC Scopus subject areas
- Physics and Astronomy(all)
- Atomic and Molecular Physics, and Optics
- Physics and Astronomy(all)
- Instrumentation
- Physics and Astronomy(all)
- Condensed Matter Physics
- Engineering(all)
- Industrial and Manufacturing Engineering
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In: Laser physics, Vol. 13, No. 5, 01.05.2003, p. 743-748.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Photodisruption with ultrashort laser pulses for intrastromal refractive surgery
AU - Heisterkamp, A.
AU - Mamom, T.
AU - Drommer, W.
AU - Ertmer, W.
AU - Lubatschowski, H.
PY - 2003/5/1
Y1 - 2003/5/1
N2 - Focusing of femtosecond laser pulses into transparent media, such as corneal tissue, leads to an optical breakdown via nonlinear absorption and cutting effects inside the tissue. Due to these nonlinear absorption processes, nearly all kinds of material can be processed by the laser, even inside the bulk of the material. The corresponding energy threshold for achieving such a cutting effect is lowered for fs pulses by several orders of magnitude as compared with ps or ns pulses. Thus, mechanical and thermal effects on the surrounding tissue can be reduced to a minimum. Based on these small side effects, precision in the μm range at cutting in biological tissue, especially in transparent corneal samples of the eye, can be achieved. Therefore, corneal flaps and lenticules for refractive surgery were created in ex vivo and in vivo eyes. The treated eyes showed the possibility of highly precise dissection and, in the case of living tissue, mild woundhealing reactions comparable to what is known from common laser procedures. Moreover, the use of the fs laser offers new possibilities in the cutting geometry that can be useful in fields of keratoplasty.
AB - Focusing of femtosecond laser pulses into transparent media, such as corneal tissue, leads to an optical breakdown via nonlinear absorption and cutting effects inside the tissue. Due to these nonlinear absorption processes, nearly all kinds of material can be processed by the laser, even inside the bulk of the material. The corresponding energy threshold for achieving such a cutting effect is lowered for fs pulses by several orders of magnitude as compared with ps or ns pulses. Thus, mechanical and thermal effects on the surrounding tissue can be reduced to a minimum. Based on these small side effects, precision in the μm range at cutting in biological tissue, especially in transparent corneal samples of the eye, can be achieved. Therefore, corneal flaps and lenticules for refractive surgery were created in ex vivo and in vivo eyes. The treated eyes showed the possibility of highly precise dissection and, in the case of living tissue, mild woundhealing reactions comparable to what is known from common laser procedures. Moreover, the use of the fs laser offers new possibilities in the cutting geometry that can be useful in fields of keratoplasty.
UR - http://www.scopus.com/inward/record.url?scp=0037803486&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:0037803486
VL - 13
SP - 743
EP - 748
JO - Laser physics
JF - Laser physics
SN - 1054-660X
IS - 5
ER -