Details
| Original language | English |
|---|---|
| Article number | 3140 |
| Journal | MOLECULES |
| Volume | 26 |
| Issue number | 11 |
| Publication status | Published - 24 May 2021 |
Abstract
The pharmacological activities in bioactive plant extracts play an increasing role in sustainable resources for valorization and biomedical applications. Bioactive phytochemicals, including natural compounds, secondary metabolites and their derivatives, have attracted significant attention for use in both medicinal products and cosmetic products. Our review highlights the pharmacological mode-of-action and current biomedical applications of key bioactive compounds applied as anti-inflammatory, bactericidal with antibiotics effects, and pain relief purposes in controlled clinical studies or preclinical studies. In this systematic review, the availability of bioactive compounds from several salt-tolerant plant species, mainly focusing on the three promising species Aster tripolium, Crithmum maritimum and Salicornia europaea, are summarized and discussed. All three of them have been widely used in natural folk medicines and are now in the focus for future nutraceutical and pharmacological applications.
Keywords
- Halophytes, Hydroxycinnamic acid, Inflammation, Nutraceuticals, Secondary metabolites
ASJC Scopus subject areas
- Chemistry(all)
- Analytical Chemistry
- Chemistry(all)
- Chemistry (miscellaneous)
- Biochemistry, Genetics and Molecular Biology(all)
- Molecular Medicine
- Pharmacology, Toxicology and Pharmaceutics(all)
- Pharmaceutical Science
- Pharmacology, Toxicology and Pharmaceutics(all)
- Drug Discovery
- Chemistry(all)
- Physical and Theoretical Chemistry
- Chemistry(all)
- Organic Chemistry
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In: MOLECULES, Vol. 26, No. 11, 3140, 24.05.2021.
Research output: Contribution to journal › Review article › Research › peer review
}
TY - JOUR
T1 - Pharmacological Insights into Halophyte Bioactive Extract Action on Anti-Inflammatory, Pain Relief and Antibiotics-Type Mechanisms
AU - Giordano, Rocco
AU - Saii, Zeinab
AU - Fredsgaard, Malthe
AU - Hulkko, Laura Sini Sofia
AU - Poulsen, Thomas Bouet Guldbæk
AU - Thomsen, Mikkel Eggert
AU - Henneberg, Nanna
AU - Zucolotto, Silvana Maria
AU - Arendt-Nielsen, Lars
AU - Papenbrock, Jutta
AU - Thomsen, Mette Hedegaard
AU - Stensballe, Allan
N1 - Funding Information: This review was funded from the European Union?s Horizon 2020 research and innovation programme under Grant Agreement No 862834.
PY - 2021/5/24
Y1 - 2021/5/24
N2 - The pharmacological activities in bioactive plant extracts play an increasing role in sustainable resources for valorization and biomedical applications. Bioactive phytochemicals, including natural compounds, secondary metabolites and their derivatives, have attracted significant attention for use in both medicinal products and cosmetic products. Our review highlights the pharmacological mode-of-action and current biomedical applications of key bioactive compounds applied as anti-inflammatory, bactericidal with antibiotics effects, and pain relief purposes in controlled clinical studies or preclinical studies. In this systematic review, the availability of bioactive compounds from several salt-tolerant plant species, mainly focusing on the three promising species Aster tripolium, Crithmum maritimum and Salicornia europaea, are summarized and discussed. All three of them have been widely used in natural folk medicines and are now in the focus for future nutraceutical and pharmacological applications.
AB - The pharmacological activities in bioactive plant extracts play an increasing role in sustainable resources for valorization and biomedical applications. Bioactive phytochemicals, including natural compounds, secondary metabolites and their derivatives, have attracted significant attention for use in both medicinal products and cosmetic products. Our review highlights the pharmacological mode-of-action and current biomedical applications of key bioactive compounds applied as anti-inflammatory, bactericidal with antibiotics effects, and pain relief purposes in controlled clinical studies or preclinical studies. In this systematic review, the availability of bioactive compounds from several salt-tolerant plant species, mainly focusing on the three promising species Aster tripolium, Crithmum maritimum and Salicornia europaea, are summarized and discussed. All three of them have been widely used in natural folk medicines and are now in the focus for future nutraceutical and pharmacological applications.
KW - Halophytes
KW - Hydroxycinnamic acid
KW - Inflammation
KW - Nutraceuticals
KW - Secondary metabolites
UR - http://www.scopus.com/inward/record.url?scp=85107405205&partnerID=8YFLogxK
U2 - 10.3390/molecules26113140
DO - 10.3390/molecules26113140
M3 - Review article
C2 - 34073962
AN - SCOPUS:85107405205
VL - 26
JO - MOLECULES
JF - MOLECULES
SN - 1420-3049
IS - 11
M1 - 3140
ER -