Details
| Original language | English |
|---|---|
| Pages (from-to) | 10-13 |
| Number of pages | 4 |
| Journal | Materials Letters |
| Volume | 195 |
| Early online date | 21 Feb 2017 |
| Publication status | Published - 15 May 2017 |
Abstract
Polyethylene oxide (PEO) and carboxymethyl cellulose (CMC)/PEO scaffolds are fabricated by electrospinning technique for soft tissue engineering applications. Morphological analysis of the scaffolds reveals formation of stable, regular and cylindrical fibers with 3-D porous interconnected network. Polyelectrolytic nature of CMC results in the formulation of thinner CMC/PEO fibers than pure PEO fibers. All the scaffolds are thermally stable and possess appreciable tensile properties to support cells and promote their growth. The non-toxicity and the ability of the scaffolds to facilitate cell proliferation are supported by MTT assay. This study contributes a promising approach to fabricate scaffolds for possible potential applications in soft tissue engineering applications.
Keywords
- Electrospinning, Fibers, Polyelectrolytic nature, Scaffold, Tensile properties
ASJC Scopus subject areas
- Materials Science(all)
- Physics and Astronomy(all)
- Condensed Matter Physics
- Engineering(all)
- Mechanics of Materials
- Engineering(all)
- Mechanical Engineering
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In: Materials Letters, Vol. 195, 15.05.2017, p. 10-13.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - PEO–CMC blend nanofibers fabrication by electrospinning for soft tissue engineering applications
AU - Basu, Poulami
AU - Repanas, Alexandros
AU - Chatterjee, Anamika
AU - Glasmacher, Birgit
AU - NarendraKumar, U.
AU - Manjubala, I.
N1 - Funding information: The author (Poulami Basu) gratefully acknowledges partial financial support from Hochschulbüro für Internationales, Leibniz Universität Hannover, Germany. This study was funded by the Niedersächsisches Ministerium für Wissenschaft und Kultur (MWK Germany) in the joint project SynFoBiA – “Novel synthesis and formulation methods for poorly soluble drugs and sensitive biopharmaceuticals”. The authors thank Mr. Bulat Sydykov, Institute for Multiphase Processes, Leibniz Universität Hannover, Germany for his assistance in FTIR and DSC.
PY - 2017/5/15
Y1 - 2017/5/15
N2 - Polyethylene oxide (PEO) and carboxymethyl cellulose (CMC)/PEO scaffolds are fabricated by electrospinning technique for soft tissue engineering applications. Morphological analysis of the scaffolds reveals formation of stable, regular and cylindrical fibers with 3-D porous interconnected network. Polyelectrolytic nature of CMC results in the formulation of thinner CMC/PEO fibers than pure PEO fibers. All the scaffolds are thermally stable and possess appreciable tensile properties to support cells and promote their growth. The non-toxicity and the ability of the scaffolds to facilitate cell proliferation are supported by MTT assay. This study contributes a promising approach to fabricate scaffolds for possible potential applications in soft tissue engineering applications.
AB - Polyethylene oxide (PEO) and carboxymethyl cellulose (CMC)/PEO scaffolds are fabricated by electrospinning technique for soft tissue engineering applications. Morphological analysis of the scaffolds reveals formation of stable, regular and cylindrical fibers with 3-D porous interconnected network. Polyelectrolytic nature of CMC results in the formulation of thinner CMC/PEO fibers than pure PEO fibers. All the scaffolds are thermally stable and possess appreciable tensile properties to support cells and promote their growth. The non-toxicity and the ability of the scaffolds to facilitate cell proliferation are supported by MTT assay. This study contributes a promising approach to fabricate scaffolds for possible potential applications in soft tissue engineering applications.
KW - Electrospinning
KW - Fibers
KW - Polyelectrolytic nature
KW - Scaffold
KW - Tensile properties
UR - http://www.scopus.com/inward/record.url?scp=85013812210&partnerID=8YFLogxK
U2 - 10.1016/j.matlet.2017.02.065
DO - 10.1016/j.matlet.2017.02.065
M3 - Article
AN - SCOPUS:85013812210
VL - 195
SP - 10
EP - 13
JO - Materials Letters
JF - Materials Letters
SN - 0167-577X
ER -