Details
| Original language | English |
|---|---|
| Pages (from-to) | 2283-2294 |
| Number of pages | 12 |
| Journal | Journal of Hypertension |
| Volume | 29 |
| Issue number | 12 |
| Publication status | Published - Dec 2011 |
| Externally published | Yes |
Abstract
Arterial hypertension is frequently encountered after renal transplantation and is associated not only with increased cardiovascular complications but also with decreased allograft survival. Adequate blood pressure control is, thus, as essential as immunologic surveillance for the long-term transplant care. Nevertheless, randomized control trials assessing treatment targets in these patients are not available and most of the evidence comes from studies in patients with native chronic kidney disease or the general population. In this regard, the renal transplant recipient is treated according to recommendations that are applicable to nontransplanted individuals at high cardiovascular risk. However, the accepted treatment targets for the nontransplanted population are recently being disputed and this makes the management of posttransplant hypertension even more challenging.
Keywords
- calcineurin inhibitors, immunosuppression, Posttransplant hypertension, renin angiotensin system, target blood pressure
ASJC Scopus subject areas
- Medicine(all)
- Internal Medicine
- Biochemistry, Genetics and Molecular Biology(all)
- Physiology
- Medicine(all)
- Cardiology and Cardiovascular Medicine
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In: Journal of Hypertension, Vol. 29, No. 12, 12.2011, p. 2283-2294.
Research output: Contribution to journal › Review article › Research › peer review
}
TY - JOUR
T1 - Pathogenesis and management of hypertension after kidney transplantation
AU - Chatzikyrkou, Christos
AU - Menne, Jan
AU - Gwinner, Wilfried
AU - Schmidt, Bernhard M.
AU - Lehner, Frank
AU - Blume, Cornelia
AU - Schwarz, Anke
AU - Haller, Hermann
AU - Schiffer, Mario
PY - 2011/12
Y1 - 2011/12
N2 - Arterial hypertension is frequently encountered after renal transplantation and is associated not only with increased cardiovascular complications but also with decreased allograft survival. Adequate blood pressure control is, thus, as essential as immunologic surveillance for the long-term transplant care. Nevertheless, randomized control trials assessing treatment targets in these patients are not available and most of the evidence comes from studies in patients with native chronic kidney disease or the general population. In this regard, the renal transplant recipient is treated according to recommendations that are applicable to nontransplanted individuals at high cardiovascular risk. However, the accepted treatment targets for the nontransplanted population are recently being disputed and this makes the management of posttransplant hypertension even more challenging.
AB - Arterial hypertension is frequently encountered after renal transplantation and is associated not only with increased cardiovascular complications but also with decreased allograft survival. Adequate blood pressure control is, thus, as essential as immunologic surveillance for the long-term transplant care. Nevertheless, randomized control trials assessing treatment targets in these patients are not available and most of the evidence comes from studies in patients with native chronic kidney disease or the general population. In this regard, the renal transplant recipient is treated according to recommendations that are applicable to nontransplanted individuals at high cardiovascular risk. However, the accepted treatment targets for the nontransplanted population are recently being disputed and this makes the management of posttransplant hypertension even more challenging.
KW - calcineurin inhibitors
KW - immunosuppression
KW - Posttransplant hypertension
KW - renin angiotensin system
KW - target blood pressure
UR - http://www.scopus.com/inward/record.url?scp=81355148692&partnerID=8YFLogxK
U2 - 10.1097/HJH.0b013e32834bd1e7
DO - 10.1097/HJH.0b013e32834bd1e7
M3 - Review article
C2 - 21970935
AN - SCOPUS:81355148692
VL - 29
SP - 2283
EP - 2294
JO - Journal of Hypertension
JF - Journal of Hypertension
SN - 0263-6352
IS - 12
ER -