Details
| Original language | English |
|---|---|
| Pages (from-to) | 5637-5639 |
| Number of pages | 3 |
| Journal | Organic letters |
| Volume | 9 |
| Issue number | 26 |
| Publication status | Published - 20 Dec 2007 |
Abstract
δ-Hydroxy-α,β-unsaturated carbonyl compounds were prepared in one step via the vinylogous Mukaiyama aldol reactions with O,O-silyl ketene acetals. Isopropyl alcohol as additive and tryptophane-based B-phenyloxazaborolidinone were required for obtaining the γ-alkylated product in high enantioselectivities.
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Biochemistry
- Chemistry(all)
- Physical and Theoretical Chemistry
- Chemistry(all)
- Organic Chemistry
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In: Organic letters, Vol. 9, No. 26, 20.12.2007, p. 5637-5639.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Oxazaborolidinone-promoted vinylogous mukaiyama aldol reactions
AU - Simsek, Serkan
AU - Horzella, Melanie
AU - Kalesse, Markus
PY - 2007/12/20
Y1 - 2007/12/20
N2 - δ-Hydroxy-α,β-unsaturated carbonyl compounds were prepared in one step via the vinylogous Mukaiyama aldol reactions with O,O-silyl ketene acetals. Isopropyl alcohol as additive and tryptophane-based B-phenyloxazaborolidinone were required for obtaining the γ-alkylated product in high enantioselectivities.
AB - δ-Hydroxy-α,β-unsaturated carbonyl compounds were prepared in one step via the vinylogous Mukaiyama aldol reactions with O,O-silyl ketene acetals. Isopropyl alcohol as additive and tryptophane-based B-phenyloxazaborolidinone were required for obtaining the γ-alkylated product in high enantioselectivities.
UR - http://www.scopus.com/inward/record.url?scp=38349084755&partnerID=8YFLogxK
U2 - 10.1021/ol702640w
DO - 10.1021/ol702640w
M3 - Article
C2 - 18052187
AN - SCOPUS:38349084755
VL - 9
SP - 5637
EP - 5639
JO - Organic letters
JF - Organic letters
SN - 1523-7060
IS - 26
ER -