Optoakustische Gewebsdifferenzierung zur Optimierung von Laserzyklophotokoagulation: Transsklerale Detektion laserinduzierter optoakustischer Drucktransienten

Research output: Contribution to journalArticleResearchpeer review

Authors

  • I. A. Bruder
  • A. Büsching
  • U. Oberheide
  • H. Lubatschowski
  • H. Welling
  • W. Ertmer

Research Organisations

External Research Organisations

  • Laser Zentrum Hannover e.V. (LZH)
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Details

Translated title of the contributionOptoacoustical tissue alteration for optimizing laser cyclophototoagulation.: Transscleral detection of laser-induced optoacoustical pressure transients
Original languageGerman
Pages (from-to)258-264
Number of pages7
JournalOPHTHALMOLOGE
Volume98
Issue number3
Publication statusPublished - Mar 2001

Abstract

Background. Considerable problems occur in transscleral laser cyclophotocoagulation concerning energy dosage. We investigated the feasibility of localizing the ciliary body by the detection of thermoelastic pressure transients and of supervising on-line the degree of tissue damage during treatment. Method. We used a specially designed handpiece to apply short pulsed laser radiation with low energy levels to enucleated bulbs of rabbits. With an adjusted pressure transducer we examined acoustical transients generated in the area of absorption of the ciliary muscle or the pigmented epithelial layer and measured axial resolution of the method at various distances to the corneoscleral limbus. Results. We detected acoustic transients that allowed rough localization of the target area. A marked change in signal was recorded with increasing level of ciliary destruction. Conclusion. This procedure can serve as an essential tool in the on-line supervision of the coagulation process. The laser parameters can thus be adjusted optimally to the progress of the treatment.

ASJC Scopus subject areas

Cite this

Optoakustische Gewebsdifferenzierung zur Optimierung von Laserzyklophotokoagulation: Transsklerale Detektion laserinduzierter optoakustischer Drucktransienten. / Bruder, I. A.; Büsching, A.; Oberheide, U. et al.
In: OPHTHALMOLOGE, Vol. 98, No. 3, 03.2001, p. 258-264.

Research output: Contribution to journalArticleResearchpeer review

Bruder IA, Büsching A, Oberheide U, Lubatschowski H, Welling H, Ertmer W. Optoakustische Gewebsdifferenzierung zur Optimierung von Laserzyklophotokoagulation: Transsklerale Detektion laserinduzierter optoakustischer Drucktransienten. OPHTHALMOLOGE. 2001 Mar;98(3):258-264. doi: 10.1007/s003470170159
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abstract = "Background. Considerable problems occur in transscleral laser cyclophotocoagulation concerning energy dosage. We investigated the feasibility of localizing the ciliary body by the detection of thermoelastic pressure transients and of supervising on-line the degree of tissue damage during treatment. Method. We used a specially designed handpiece to apply short pulsed laser radiation with low energy levels to enucleated bulbs of rabbits. With an adjusted pressure transducer we examined acoustical transients generated in the area of absorption of the ciliary muscle or the pigmented epithelial layer and measured axial resolution of the method at various distances to the corneoscleral limbus. Results. We detected acoustic transients that allowed rough localization of the target area. A marked change in signal was recorded with increasing level of ciliary destruction. Conclusion. This procedure can serve as an essential tool in the on-line supervision of the coagulation process. The laser parameters can thus be adjusted optimally to the progress of the treatment.",
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Download

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T1 - Optoakustische Gewebsdifferenzierung zur Optimierung von Laserzyklophotokoagulation

T2 - Transsklerale Detektion laserinduzierter optoakustischer Drucktransienten

AU - Bruder, I. A.

AU - Büsching, A.

AU - Oberheide, U.

AU - Lubatschowski, H.

AU - Welling, H.

AU - Ertmer, W.

PY - 2001/3

Y1 - 2001/3

N2 - Background. Considerable problems occur in transscleral laser cyclophotocoagulation concerning energy dosage. We investigated the feasibility of localizing the ciliary body by the detection of thermoelastic pressure transients and of supervising on-line the degree of tissue damage during treatment. Method. We used a specially designed handpiece to apply short pulsed laser radiation with low energy levels to enucleated bulbs of rabbits. With an adjusted pressure transducer we examined acoustical transients generated in the area of absorption of the ciliary muscle or the pigmented epithelial layer and measured axial resolution of the method at various distances to the corneoscleral limbus. Results. We detected acoustic transients that allowed rough localization of the target area. A marked change in signal was recorded with increasing level of ciliary destruction. Conclusion. This procedure can serve as an essential tool in the on-line supervision of the coagulation process. The laser parameters can thus be adjusted optimally to the progress of the treatment.

AB - Background. Considerable problems occur in transscleral laser cyclophotocoagulation concerning energy dosage. We investigated the feasibility of localizing the ciliary body by the detection of thermoelastic pressure transients and of supervising on-line the degree of tissue damage during treatment. Method. We used a specially designed handpiece to apply short pulsed laser radiation with low energy levels to enucleated bulbs of rabbits. With an adjusted pressure transducer we examined acoustical transients generated in the area of absorption of the ciliary muscle or the pigmented epithelial layer and measured axial resolution of the method at various distances to the corneoscleral limbus. Results. We detected acoustic transients that allowed rough localization of the target area. A marked change in signal was recorded with increasing level of ciliary destruction. Conclusion. This procedure can serve as an essential tool in the on-line supervision of the coagulation process. The laser parameters can thus be adjusted optimally to the progress of the treatment.

KW - Glaucoma

KW - Laser cyclophotocoagulation

KW - On-line supervision mechanism

KW - Optoacoustics

KW - Pressure transients

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