Optoacoust ical Tissue D ifferentiat ion For On-Line Therapy Control

Research output: Chapter in book/report/conference proceedingConference contributionResearchpeer review

Authors

  • Uwe Oberheide
  • Birte Jansen
  • Ingo Bruder
  • Holger Lubatschowski
  • Herbert Welling
  • Wolfgang Ertmer

Research Organisations

External Research Organisations

  • Laser Zentrum Hannover e.V. (LZH)
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Details

Original languageEnglish
Title of host publicationOptical Biopsy and Tissue Optics
PublisherSPIE
Pages37-45
Number of pages9
Publication statusPublished - 16 Nov 2000
EventEOS/SPIE European Biomedical Optics Week - Amsterdam, Netherlands
Duration: 4 Jul 20008 Jul 2000

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume4161
ISSN (Print)0277-786X

Abstract

In this work, the localization of the ciliary body region of porcine eyes with laser optoacoustics was realized. The principle of laser optoacoustics combines the advantages of ultrasound and optical tomography. The absorption of short laser pulses in the near infrared generates thermoelastic stress waves in the ciliary muscle and the underlying pigmented epithelial layers. These stress transients were detected at the surface of the sclera with piezoelectric transducers in order to analyze the structure. The optoacoustical measurements of the ciliary body region at different positions from the corneoscleral limbus were composed to a grayscale image, which could be qualitatively compared to histological sections of this region. In these images the pigmented layers can be localized. The influence of the detectional wavelength on the optoacoustical signal in the NIR between 750 and 1052 nm was investigated. Furthermore, changes in the optoacoustic signal due to coagulation with a diode laser using typical therapeutical parameters could be observed.

Keywords

    Ciliary body, Glaucoma, Laser cyclophotocoagulation, Laser induced ultrasound, Optoacoustics, Pressure transient

ASJC Scopus subject areas

Cite this

Optoacoust ical Tissue D ifferentiat ion For On-Line Therapy Control. / Oberheide, Uwe; Jansen, Birte; Bruder, Ingo et al.
Optical Biopsy and Tissue Optics. SPIE, 2000. p. 37-45 (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 4161).

Research output: Chapter in book/report/conference proceedingConference contributionResearchpeer review

Oberheide, U, Jansen, B, Bruder, I, Lubatschowski, H, Welling, H & Ertmer, W 2000, Optoacoust ical Tissue D ifferentiat ion For On-Line Therapy Control. in Optical Biopsy and Tissue Optics. Proceedings of SPIE - The International Society for Optical Engineering, vol. 4161, SPIE, pp. 37-45, EOS/SPIE European Biomedical Optics Week, Amsterdam, Netherlands, 4 Jul 2000. https://doi.org/10.1117/12.409333
Oberheide, U., Jansen, B., Bruder, I., Lubatschowski, H., Welling, H., & Ertmer, W. (2000). Optoacoust ical Tissue D ifferentiat ion For On-Line Therapy Control. In Optical Biopsy and Tissue Optics (pp. 37-45). (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 4161). SPIE. https://doi.org/10.1117/12.409333
Oberheide U, Jansen B, Bruder I, Lubatschowski H, Welling H, Ertmer W. Optoacoust ical Tissue D ifferentiat ion For On-Line Therapy Control. In Optical Biopsy and Tissue Optics. SPIE. 2000. p. 37-45. (Proceedings of SPIE - The International Society for Optical Engineering). doi: 10.1117/12.409333
Oberheide, Uwe ; Jansen, Birte ; Bruder, Ingo et al. / Optoacoust ical Tissue D ifferentiat ion For On-Line Therapy Control. Optical Biopsy and Tissue Optics. SPIE, 2000. pp. 37-45 (Proceedings of SPIE - The International Society for Optical Engineering).
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abstract = "In this work, the localization of the ciliary body region of porcine eyes with laser optoacoustics was realized. The principle of laser optoacoustics combines the advantages of ultrasound and optical tomography. The absorption of short laser pulses in the near infrared generates thermoelastic stress waves in the ciliary muscle and the underlying pigmented epithelial layers. These stress transients were detected at the surface of the sclera with piezoelectric transducers in order to analyze the structure. The optoacoustical measurements of the ciliary body region at different positions from the corneoscleral limbus were composed to a grayscale image, which could be qualitatively compared to histological sections of this region. In these images the pigmented layers can be localized. The influence of the detectional wavelength on the optoacoustical signal in the NIR between 750 and 1052 nm was investigated. Furthermore, changes in the optoacoustic signal due to coagulation with a diode laser using typical therapeutical parameters could be observed.",
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