Details
Original language | English |
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Title of host publication | Ophthalmic Technologies XI; |
Pages | 246-254 |
Number of pages | 9 |
Publication status | Published - 7 Jun 2001 |
Event | Bios 2001 The International Symposium on Biomedical Optics - San Jose, CA, United States Duration: 20 Jan 2001 → 26 Jan 2001 |
Publication series
Name | Proceedings of SPIE - The International Society for Optical Engineering |
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Volume | 4245 |
ISSN (Print) | 0277-786X |
Abstract
Focussing femtosecond laser pulses into a transparent media, such as corneal tissue, leads to optical breakdown, generation of a micro-plasma and, thus, a cutting effect inside the tissue. To proof the potential of fs-lasers in refractive surgery, three-dimensional cutting within the corneal stroma was evaluated. With the use of ultrashort laser pulses within the LASIK procedure (laser in situ keratomileusis) possible complications in handling of a mechanical knife, the microkeratome, can be reduced by using the treatment laser as the keratome itself. To study woundhealing effects, animal studies were carried out in rabbit specimen. The surgical outcome was analysed by means of histological sections; as well as light and scanning electron microscopy. Dependencies on the dispersion caused by focussing optics were evaluated and optimized. Thus, pulse energies well below 1 μJ were sufficient to perform the intrastromal cuts. The laser pulses with a duration of 180 fs and energies of 0.5-100 μJ were provided by a modelocked frequency doubled erbium fiber-laser with subsequent chirped pulse amplification in a titanium sapphire amplifier at up to 3 kHz.
Keywords
- Femtosecond laser, Laser pulses, Photodisruption, Photodissociation, Refractive surgery, Ultrashort
ASJC Scopus subject areas
- Materials Science(all)
- Electronic, Optical and Magnetic Materials
- Physics and Astronomy(all)
- Condensed Matter Physics
- Computer Science(all)
- Computer Science Applications
- Mathematics(all)
- Applied Mathematics
- Engineering(all)
- Electrical and Electronic Engineering
Cite this
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Ophthalmic Technologies XI;. 2001. p. 246-254 (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 4245).
Research output: Chapter in book/report/conference proceeding › Conference contribution › Research › peer review
}
TY - GEN
T1 - Optimization of the Parameters for Intrastromal Refractive Surgery with Ultrashort Laser Pulses
AU - Heisterkamp, A.
AU - Ripken, T.
AU - Lubatschowski, H.
AU - Welling, H.
AU - Drommer, W.
AU - Lu�tkefels, E.
AU - Mamom, T.
AU - Ertmer, W.
PY - 2001/6/7
Y1 - 2001/6/7
N2 - Focussing femtosecond laser pulses into a transparent media, such as corneal tissue, leads to optical breakdown, generation of a micro-plasma and, thus, a cutting effect inside the tissue. To proof the potential of fs-lasers in refractive surgery, three-dimensional cutting within the corneal stroma was evaluated. With the use of ultrashort laser pulses within the LASIK procedure (laser in situ keratomileusis) possible complications in handling of a mechanical knife, the microkeratome, can be reduced by using the treatment laser as the keratome itself. To study woundhealing effects, animal studies were carried out in rabbit specimen. The surgical outcome was analysed by means of histological sections; as well as light and scanning electron microscopy. Dependencies on the dispersion caused by focussing optics were evaluated and optimized. Thus, pulse energies well below 1 μJ were sufficient to perform the intrastromal cuts. The laser pulses with a duration of 180 fs and energies of 0.5-100 μJ were provided by a modelocked frequency doubled erbium fiber-laser with subsequent chirped pulse amplification in a titanium sapphire amplifier at up to 3 kHz.
AB - Focussing femtosecond laser pulses into a transparent media, such as corneal tissue, leads to optical breakdown, generation of a micro-plasma and, thus, a cutting effect inside the tissue. To proof the potential of fs-lasers in refractive surgery, three-dimensional cutting within the corneal stroma was evaluated. With the use of ultrashort laser pulses within the LASIK procedure (laser in situ keratomileusis) possible complications in handling of a mechanical knife, the microkeratome, can be reduced by using the treatment laser as the keratome itself. To study woundhealing effects, animal studies were carried out in rabbit specimen. The surgical outcome was analysed by means of histological sections; as well as light and scanning electron microscopy. Dependencies on the dispersion caused by focussing optics were evaluated and optimized. Thus, pulse energies well below 1 μJ were sufficient to perform the intrastromal cuts. The laser pulses with a duration of 180 fs and energies of 0.5-100 μJ were provided by a modelocked frequency doubled erbium fiber-laser with subsequent chirped pulse amplification in a titanium sapphire amplifier at up to 3 kHz.
KW - Femtosecond laser
KW - Laser pulses
KW - Photodisruption
KW - Photodissociation
KW - Refractive surgery
KW - Ultrashort
UR - http://www.scopus.com/inward/record.url?scp=0034859277&partnerID=8YFLogxK
U2 - 10.1117/12.429279
DO - 10.1117/12.429279
M3 - Conference contribution
AN - SCOPUS:0034859277
T3 - Proceedings of SPIE - The International Society for Optical Engineering
SP - 246
EP - 254
BT - Ophthalmic Technologies XI;
T2 - Bios 2001 The International Symposium on Biomedical Optics
Y2 - 20 January 2001 through 26 January 2001
ER -