Details
| Original language | English |
|---|---|
| Pages (from-to) | 763-769 |
| Number of pages | 7 |
| Journal | Sensors and Actuators, B: Chemical |
| Volume | 204 |
| Publication status | Published - 19 Aug 2014 |
Abstract
The major task in most autopsies is the evaluation of circumstances and cause of a person's death. The quantification of edema, primarily in certain brain regions, is a promising marker to distinguish between certain causes of death. This is especially important if there is no visible reason, for example, in the case of distinguishing Sudden Infant Death Syndrome from Shaken Impact Syndrome. However, until now there is no standardized procedure in forensic medicine for the quantification of edema in parenchymatous organs. Therefore, the aim of our work is to develop a fast low-cost measuring system that fits into the procedure of an autopsy. One approach for an exact quantification of edema is to determine the humidity content in the tissue with the so-called oven dry method, which we used as a reference. The approach presented here is the determination of the humidity content via a measurement of the relative permittivity of the tissue. We use two different setups: a transmission and a reflection measurement. Thereby a linear regression between the humidity content and the relative permittivity was found with excellent regression coefficients of R = 0.98 for the transmission measurement and R = 0.97 for the reflection measurement. We compare the results of the used methods regarding accuracy and measuring time.
Keywords
- Aquametry, Material characterization, Open-ended coaxial probe, Permittivity measurement, Permittivity of brain tissue
ASJC Scopus subject areas
- Materials Science(all)
- Electronic, Optical and Magnetic Materials
- Physics and Astronomy(all)
- Instrumentation
- Physics and Astronomy(all)
- Condensed Matter Physics
- Materials Science(all)
- Surfaces, Coatings and Films
- Materials Science(all)
- Metals and Alloys
- Engineering(all)
- Electrical and Electronic Engineering
- Materials Science(all)
- Materials Chemistry
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In: Sensors and Actuators, B: Chemical, Vol. 204, 19.08.2014, p. 763-769.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Open-ended coaxial probe for the quantification of edema in human brain tissue
AU - Reinecke, T.
AU - Hagemeier, L.
AU - Spehlbrink, H.
AU - Guenther, S.
AU - Klintschar, M.
AU - Zimmermann, S.
PY - 2014/8/19
Y1 - 2014/8/19
N2 - The major task in most autopsies is the evaluation of circumstances and cause of a person's death. The quantification of edema, primarily in certain brain regions, is a promising marker to distinguish between certain causes of death. This is especially important if there is no visible reason, for example, in the case of distinguishing Sudden Infant Death Syndrome from Shaken Impact Syndrome. However, until now there is no standardized procedure in forensic medicine for the quantification of edema in parenchymatous organs. Therefore, the aim of our work is to develop a fast low-cost measuring system that fits into the procedure of an autopsy. One approach for an exact quantification of edema is to determine the humidity content in the tissue with the so-called oven dry method, which we used as a reference. The approach presented here is the determination of the humidity content via a measurement of the relative permittivity of the tissue. We use two different setups: a transmission and a reflection measurement. Thereby a linear regression between the humidity content and the relative permittivity was found with excellent regression coefficients of R = 0.98 for the transmission measurement and R = 0.97 for the reflection measurement. We compare the results of the used methods regarding accuracy and measuring time.
AB - The major task in most autopsies is the evaluation of circumstances and cause of a person's death. The quantification of edema, primarily in certain brain regions, is a promising marker to distinguish between certain causes of death. This is especially important if there is no visible reason, for example, in the case of distinguishing Sudden Infant Death Syndrome from Shaken Impact Syndrome. However, until now there is no standardized procedure in forensic medicine for the quantification of edema in parenchymatous organs. Therefore, the aim of our work is to develop a fast low-cost measuring system that fits into the procedure of an autopsy. One approach for an exact quantification of edema is to determine the humidity content in the tissue with the so-called oven dry method, which we used as a reference. The approach presented here is the determination of the humidity content via a measurement of the relative permittivity of the tissue. We use two different setups: a transmission and a reflection measurement. Thereby a linear regression between the humidity content and the relative permittivity was found with excellent regression coefficients of R = 0.98 for the transmission measurement and R = 0.97 for the reflection measurement. We compare the results of the used methods regarding accuracy and measuring time.
KW - Aquametry
KW - Material characterization
KW - Open-ended coaxial probe
KW - Permittivity measurement
KW - Permittivity of brain tissue
UR - http://www.scopus.com/inward/record.url?scp=84906861519&partnerID=8YFLogxK
U2 - 10.1016/j.snb.2014.08.045
DO - 10.1016/j.snb.2014.08.045
M3 - Article
AN - SCOPUS:84906861519
VL - 204
SP - 763
EP - 769
JO - Sensors and Actuators, B: Chemical
JF - Sensors and Actuators, B: Chemical
SN - 0925-4005
ER -