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Numerical investigations on the osseointegration of uncemented endoprostheses based on bio-active interface theory

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Original languageEnglish
Pages (from-to)367-381
Number of pages15
JournalComputational mechanics
Volume50
Issue number3
Publication statusPublished - Sept 2012

Abstract

In order to simulate the osseointegration of bone implants, a bio-active interface theory is necessary. The thin bone-implant interface layer is described by the Drucker- Prager plasticity model. The formulation of bone mineral density depends on the local mechanical environment. For the simulation of the osseointegration of bone implants a bio-active interface theory is suggested. A thin bone-implant interface layer is described by a Drucker-Prager plasticity model. An evolution rule for the bone mineral density is formulated in dependency of the local mechanical environment. The time dependent ingrowth is modeled by a hardening rule which modifies the Drucker-Prager yield-surface cone in the principle stress state in dependency of the local bone mineral density. The osseointegration process is limited by the violation of a so called micromotion threshold. This relative motion in the implant-bone interface is computed by dynamic loads of daily motion activity. For parameter studies on detailed 3D models model reduction techniques are introduced. The applicability is demonstrated on a hip-joint prosthesis which is in clinical usage.

Keywords

    Bone-implant interface, Finite element simulation, Hip-joint prostheses, Micromotion, Model reduction, Osseointegration

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Numerical investigations on the osseointegration of uncemented endoprostheses based on bio-active interface theory. / Lutz, André; Nackenhorst, Udo.
In: Computational mechanics, Vol. 50, No. 3, 09.2012, p. 367-381.

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abstract = "In order to simulate the osseointegration of bone implants, a bio-active interface theory is necessary. The thin bone-implant interface layer is described by the Drucker- Prager plasticity model. The formulation of bone mineral density depends on the local mechanical environment. For the simulation of the osseointegration of bone implants a bio-active interface theory is suggested. A thin bone-implant interface layer is described by a Drucker-Prager plasticity model. An evolution rule for the bone mineral density is formulated in dependency of the local mechanical environment. The time dependent ingrowth is modeled by a hardening rule which modifies the Drucker-Prager yield-surface cone in the principle stress state in dependency of the local bone mineral density. The osseointegration process is limited by the violation of a so called micromotion threshold. This relative motion in the implant-bone interface is computed by dynamic loads of daily motion activity. For parameter studies on detailed 3D models model reduction techniques are introduced. The applicability is demonstrated on a hip-joint prosthesis which is in clinical usage.",
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Download

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AU - Lutz, André

AU - Nackenhorst, Udo

PY - 2012/9

Y1 - 2012/9

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KW - Bone-implant interface

KW - Finite element simulation

KW - Hip-joint prostheses

KW - Micromotion

KW - Model reduction

KW - Osseointegration

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