Noninvasive Risk Prediction Models for Heart Failure Using Proportional Jaccard Indices and Comorbidity Patterns

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Authors

  • Yueh Tang
  • Chao Hung Wang
  • Prasenjit Mitra
  • Tun Wen Pai

Research Organisations

External Research Organisations

  • National Taipei University of Technology
  • Chang Gung University
  • Pennsylvania State University
  • National Taiwan Ocean University
  • Chang Gung Memorial Hospital
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Details

Original languageEnglish
Article number179
Number of pages13
JournalReviews in cardiovascular medicine
Volume25
Issue number5
Publication statusPublished - 20 May 2024

Abstract

Background: In the post-coronavirus disease 2019 (COVID-19) era, remote diagnosis and precision preventive medicine have emerged as pivotal clinical medicine applications. This study aims to develop a digital health-monitoring tool that utilizes electronic medical records (EMRs) as the foundation for performing a non-random correlation analysis among different comorbidity patterns for heart failure (HF). Methods: Novel similarity indices, including proportional Jaccard index (PJI), multiplication of the odds ratio proportional Jaccard index (OPJI), and alpha proportional Jaccard index (APJI), provide a fundamental framework for constructing machine learning models to predict the risk conditions associated with HF. Results: Our models were constructed for different age groups and sexes and yielded accurate predictions of high-risk HF across demographics. The results indicated that the optimal prediction model achieved a notable accuracy of 82.1% and an area under the curve (AUC) of 0.878. Conclusions: Our noninvasive HF risk prediction system is based on historical EMRs and provides a practical approach. The proposed indices provided simple and straightforward comparative indicators of comorbidity pattern matching within individual EMRs. All source codes developed for our noninvasive prediction models can be retrieved from GitHub.

Keywords

    alpha index, alpha proportional jaccard index, electronic medical records, heart failure, odds ratio, odds ratio proportional jaccard index, precision prevention, proportional jaccard index, telehealth

ASJC Scopus subject areas

Cite this

Noninvasive Risk Prediction Models for Heart Failure Using Proportional Jaccard Indices and Comorbidity Patterns. / Tang, Yueh; Wang, Chao Hung; Mitra, Prasenjit et al.
In: Reviews in cardiovascular medicine, Vol. 25, No. 5, 179, 20.05.2024.

Research output: Contribution to journalArticleResearchpeer review

Download
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AU - Mitra, Prasenjit

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