Details
| Original language | English |
|---|---|
| Article number | 131 |
| Number of pages | 28 |
| Journal | TOXINS |
| Volume | 16 |
| Issue number | 3 |
| Publication status | Published - 2 Mar 2024 |
Abstract
RNA viruses of the genera Ambivirus, Mitovirus, Sclerotimonavirus, and Partitivirus were found in a single isolate of Fusarium graminearum. The genomes of the mitovirus, sclerotimonavirus, and partitivirus were assigned to previously described viruses, whereas the ambivirus genome putatively represents a new species, named Fusarium graminearum ambivirus 1 (FgAV1). To investigate the effect of mycoviruses on the fungal phenotype, the spontaneous loss of mycoviruses during meiosis and the transmission of mycoviruses into a new strain via anastomosis were used to obtain isogenic F. graminearum strains both with and without mycoviruses. Notable effects observed in mycovirus-harboring strains were (i) the suppression of the synthesis of trichothecene mycotoxins and their precursor trichodiene, (ii) the suppression of the synthesis of the defense compound aurofusarin, (iii) the stimulation of the emission of 2-methyl-1-butanol and 3-methyl-1-butanol, and (iv) the increased attractiveness of fungal mycelia for fungivorous collembolans. The increased attractiveness of mycovirus-infected filamentous fungi to animal predators opens new perspectives on the ecological implications of the infection of fungi with viruses.
Keywords
- aurofusarin, Collembola, deoxynivalenol, Folsomia candida, food preference, fungivory, Fusarium graminearum, mycovirus, trichothecenes, VOC
ASJC Scopus subject areas
- Pharmacology, Toxicology and Pharmaceutics(all)
- Toxicology
- Environmental Science(all)
- Health, Toxicology and Mutagenesis
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In: TOXINS, Vol. 16, No. 3, 131, 02.03.2024.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Mycoviruses Increase the Attractiveness of Fusarium graminearum for Fungivores and Suppress Production of the Mycotoxin Deoxynivalenol
AU - Schiwek, Simon
AU - Slonka, Matthäus
AU - Alhussein, Mohammad
AU - Knierim, Dennis
AU - Margaria, Paolo
AU - Rose, Hanna
AU - Richert-Pöggeler, Katja R.
AU - Rostás, Michael
AU - Karlovsky, Petr
PY - 2024/3/2
Y1 - 2024/3/2
N2 - RNA viruses of the genera Ambivirus, Mitovirus, Sclerotimonavirus, and Partitivirus were found in a single isolate of Fusarium graminearum. The genomes of the mitovirus, sclerotimonavirus, and partitivirus were assigned to previously described viruses, whereas the ambivirus genome putatively represents a new species, named Fusarium graminearum ambivirus 1 (FgAV1). To investigate the effect of mycoviruses on the fungal phenotype, the spontaneous loss of mycoviruses during meiosis and the transmission of mycoviruses into a new strain via anastomosis were used to obtain isogenic F. graminearum strains both with and without mycoviruses. Notable effects observed in mycovirus-harboring strains were (i) the suppression of the synthesis of trichothecene mycotoxins and their precursor trichodiene, (ii) the suppression of the synthesis of the defense compound aurofusarin, (iii) the stimulation of the emission of 2-methyl-1-butanol and 3-methyl-1-butanol, and (iv) the increased attractiveness of fungal mycelia for fungivorous collembolans. The increased attractiveness of mycovirus-infected filamentous fungi to animal predators opens new perspectives on the ecological implications of the infection of fungi with viruses.
AB - RNA viruses of the genera Ambivirus, Mitovirus, Sclerotimonavirus, and Partitivirus were found in a single isolate of Fusarium graminearum. The genomes of the mitovirus, sclerotimonavirus, and partitivirus were assigned to previously described viruses, whereas the ambivirus genome putatively represents a new species, named Fusarium graminearum ambivirus 1 (FgAV1). To investigate the effect of mycoviruses on the fungal phenotype, the spontaneous loss of mycoviruses during meiosis and the transmission of mycoviruses into a new strain via anastomosis were used to obtain isogenic F. graminearum strains both with and without mycoviruses. Notable effects observed in mycovirus-harboring strains were (i) the suppression of the synthesis of trichothecene mycotoxins and their precursor trichodiene, (ii) the suppression of the synthesis of the defense compound aurofusarin, (iii) the stimulation of the emission of 2-methyl-1-butanol and 3-methyl-1-butanol, and (iv) the increased attractiveness of fungal mycelia for fungivorous collembolans. The increased attractiveness of mycovirus-infected filamentous fungi to animal predators opens new perspectives on the ecological implications of the infection of fungi with viruses.
KW - aurofusarin
KW - Collembola
KW - deoxynivalenol
KW - Folsomia candida
KW - food preference
KW - fungivory
KW - Fusarium graminearum
KW - mycovirus
KW - trichothecenes
KW - VOC
UR - http://www.scopus.com/inward/record.url?scp=85188964098&partnerID=8YFLogxK
U2 - 10.3390/toxins16030131
DO - 10.3390/toxins16030131
M3 - Article
AN - SCOPUS:85188964098
VL - 16
JO - TOXINS
JF - TOXINS
SN - 2072-6651
IS - 3
M1 - 131
ER -