Details
| Original language | English |
|---|---|
| Pages (from-to) | 2040-2042 |
| Number of pages | 3 |
| Journal | Chemical communications |
| Issue number | 20 |
| Publication status | Published - 1 Jan 2007 |
| Externally published | Yes |
Abstract
Mutation of the HMG-CoA synthase encoding mupH gene in Pseudomonas fluorescens gives rise to a new metabolite formed from a truncated polyketide intermediate, providing in vivo evidence for the roles of mupH and cognate genes found in several "AT-less" and other bacterial PKS gene clusters responsible for the biosynthesis of diverse metabolites containing acetate/propionate derived side chains.
ASJC Scopus subject areas
- Chemical Engineering(all)
- Catalysis
- Materials Science(all)
- Electronic, Optical and Magnetic Materials
- Materials Science(all)
- Ceramics and Composites
- Chemistry(all)
- General Chemistry
- Materials Science(all)
- Surfaces, Coatings and Films
- Materials Science(all)
- Metals and Alloys
- Materials Science(all)
- Materials Chemistry
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In: Chemical communications, No. 20, 01.01.2007, p. 2040-2042.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Mupirocin H, a novel metabolite resulting from mutation of the HMG-CoA synthase analogue, mupH in Pseudomonas fluorescens
AU - Wu, Ji'En
AU - Cooper, Sian M.
AU - Cox, Russell J.
AU - Crosby, John
AU - Crump, Matthew P.
AU - Hothersall, Joanne
AU - Simpson, Thomas J.
AU - Thomas, Christopher M.
AU - Willis, Christine L.
PY - 2007/1/1
Y1 - 2007/1/1
N2 - Mutation of the HMG-CoA synthase encoding mupH gene in Pseudomonas fluorescens gives rise to a new metabolite formed from a truncated polyketide intermediate, providing in vivo evidence for the roles of mupH and cognate genes found in several "AT-less" and other bacterial PKS gene clusters responsible for the biosynthesis of diverse metabolites containing acetate/propionate derived side chains.
AB - Mutation of the HMG-CoA synthase encoding mupH gene in Pseudomonas fluorescens gives rise to a new metabolite formed from a truncated polyketide intermediate, providing in vivo evidence for the roles of mupH and cognate genes found in several "AT-less" and other bacterial PKS gene clusters responsible for the biosynthesis of diverse metabolites containing acetate/propionate derived side chains.
UR - http://www.scopus.com/inward/record.url?scp=34250776587&partnerID=8YFLogxK
U2 - 10.1039/b700613f
DO - 10.1039/b700613f
M3 - Article
C2 - 17713071
AN - SCOPUS:34250776587
SP - 2040
EP - 2042
JO - Chemical communications
JF - Chemical communications
SN - 1359-7345
IS - 20
ER -