Details
| Original language | English |
|---|---|
| Pages (from-to) | 330-335 |
| Number of pages | 6 |
| Journal | Green chemistry |
| Volume | 15 |
| Issue number | 2 |
| Early online date | 20 Dec 2012 |
| Publication status | Published - Feb 2013 |
| Externally published | Yes |
Abstract
1,4-Butanediol is shown to be an efficient cosubstrate to promote NAD(P)H-dependent redox biocatalysis. The thermodynamically and kinetically inert lactone coproduct makes the regeneration reaction irreversible. Thereby not only the molar surplus of cosubstrate is dramatically reduced but also faster reaction rates are obtained.
ASJC Scopus subject areas
- Environmental Science(all)
- Environmental Chemistry
- Environmental Science(all)
- Pollution
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In: Green chemistry, Vol. 15, No. 2, 02.2013, p. 330-335.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - More efficient redox biocatalysis by utilising 1,4-butanediol as a 'smart cosubstrate'
AU - Kara, Selin
AU - Spickermann, Dominik
AU - Schrittwieser, Joerg H.
AU - Leggewie, Christian
AU - Van Berkel, Willem J.H.
AU - Arends, Isabel W.C.E.
AU - Hollmann, Frank
PY - 2013/2
Y1 - 2013/2
N2 - 1,4-Butanediol is shown to be an efficient cosubstrate to promote NAD(P)H-dependent redox biocatalysis. The thermodynamically and kinetically inert lactone coproduct makes the regeneration reaction irreversible. Thereby not only the molar surplus of cosubstrate is dramatically reduced but also faster reaction rates are obtained.
AB - 1,4-Butanediol is shown to be an efficient cosubstrate to promote NAD(P)H-dependent redox biocatalysis. The thermodynamically and kinetically inert lactone coproduct makes the regeneration reaction irreversible. Thereby not only the molar surplus of cosubstrate is dramatically reduced but also faster reaction rates are obtained.
UR - http://www.scopus.com/inward/record.url?scp=84873321013&partnerID=8YFLogxK
U2 - 10.1039/c2gc36797a
DO - 10.1039/c2gc36797a
M3 - Article
AN - SCOPUS:84873321013
VL - 15
SP - 330
EP - 335
JO - Green chemistry
JF - Green chemistry
SN - 1463-9262
IS - 2
ER -