Details
| Original language | English |
|---|---|
| Pages (from-to) | 3622-3635 |
| Number of pages | 14 |
| Journal | RSC Advances |
| Volume | 11 |
| Issue number | 6 |
| Publication status | Published - 18 Jan 2021 |
Abstract
Members of the genus Trichoderma are a well-established and studied group of fungi, mainly due to their efficient protein production capabilities and their biocontrol activities. Despite the immense interest in the use of different members of this species as biopesticides and biofertilizers, the study of their active metabolites and their biosynthetic gene clusters has not gained significant attention until recently. Here we review the challenges and opportunities in exploiting the full potential of Trichoderma spp. for the production of natural products and new metabolic engineering strategies used to overcome some of these challenges.
ASJC Scopus subject areas
- Chemistry(all)
- General Chemistry
- Chemical Engineering(all)
- General Chemical Engineering
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In: RSC Advances, Vol. 11, No. 6, 18.01.2021, p. 3622-3635.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Molecular methods unravel the biosynthetic potential of Trichoderma species
AU - Shenouda, Mary L.
AU - Cox, Russell J.
N1 - Funding Information: MLS thanks the German Academic Exchange Service (DAAD) and the Egyptian Ministry of Higher Education and Scientic Research (MHESR) for funding (GERLS programme, 2017, 57311832).
PY - 2021/1/18
Y1 - 2021/1/18
N2 - Members of the genus Trichoderma are a well-established and studied group of fungi, mainly due to their efficient protein production capabilities and their biocontrol activities. Despite the immense interest in the use of different members of this species as biopesticides and biofertilizers, the study of their active metabolites and their biosynthetic gene clusters has not gained significant attention until recently. Here we review the challenges and opportunities in exploiting the full potential of Trichoderma spp. for the production of natural products and new metabolic engineering strategies used to overcome some of these challenges.
AB - Members of the genus Trichoderma are a well-established and studied group of fungi, mainly due to their efficient protein production capabilities and their biocontrol activities. Despite the immense interest in the use of different members of this species as biopesticides and biofertilizers, the study of their active metabolites and their biosynthetic gene clusters has not gained significant attention until recently. Here we review the challenges and opportunities in exploiting the full potential of Trichoderma spp. for the production of natural products and new metabolic engineering strategies used to overcome some of these challenges.
UR - http://www.scopus.com/inward/record.url?scp=85100041845&partnerID=8YFLogxK
U2 - 10.1039/d0ra09627j
DO - 10.1039/d0ra09627j
M3 - Article
VL - 11
SP - 3622
EP - 3635
JO - RSC Advances
JF - RSC Advances
SN - 2046-2069
IS - 6
ER -